Results 41 to 50 of about 38,393 (221)

Effect of lifestyle intervention plus rosiglitazone or placebo therapy on left ventricular mass assessed with cardiovascular magnetic resonance in the metabolic syndrome [PDF]

, 2011
Background To evaluate the effect of lifestyle intervention in conjunction with rosiglitazone or placebo therapy on left ventricular (LV) mass, using cardiovascular magnetic resonance (CMR) in the metabolic syndrome.
Stijntje D Roes, Reza A Dehnavi, Jos JM Westenberg, Hildo J Lamb, Bart JA Mertens, Jouke T Tamsma, Albert de Roos   +6 more
core   +1 more source

Trends in the utilization, expenditure and costs of noninsulin glucose‐lowering drugs in the Medicaid population: Steady increases in glucagon‐like peptide‐1 receptor agonist and sodium–glucose transporter‐2 inhibitor use, prices and expenditure

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to analyse changes in the utilization, expenditure and average cost of noninsulin glucose‐lowering drugs (GLDs) between 2008 and 2023. Methods This was a retrospective observational study of 2008–2023 data from the National Medicaid State Drug Utilization database.
Rawan O. Almadfaa
wiley   +1 more source

Clinical pharmacology and prescribing education: An updated medical school curriculum from the British Pharmacological Society

British Journal of Clinical Pharmacology, EarlyView.
Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale, Clare Guilding, Jennifer Koenig, Michael Okorie, Reecha Sofat, Simon Maxwell   +5 more
wiley   +1 more source

How do new therapeutic strategies for PCOS management influence the health of the affected individuals? The narrative review

Journal of Education, Health and Sport, 2022
Introduction and purpose: Management of polycystic ovary syndrome (PCOS) is difficult since the exact pathogenic mechanism has not been established yet.
Aleksandra Wójcik, Jan Wojtas, Mikołaj Margas, Konrad Warchoł, Karol Stępniak   +4 more
doaj   +1 more source

RPB4 and pathogenesis of diabetes [PDF]

, 2007
Obesity is an important risk factor for a number of chronic diseases that impose a huge burden on individuals and society. Recently it has become clear that adipose tissue-secreted products may play a significant role in mediating many obesity-related ...
Kumar, Sudhesh, McTernan, P. G. (Philip G.)   +1 more
core   +1 more source

GLP‐1 agonists and the gut microbiome: A bidirectional relationship

British Journal of Clinical Pharmacology, EarlyView.
Abstract Glucagon‐like peptide‐1 (GLP‐1) receptor agonists have transformed the management of type 2 diabetes mellitus (T2DM) and obesity, yet their interactions with the gut microbiome remain an emerging frontier in pharmacological and metabolic research.
Srinivas Kamath, Nicole S. L. Chan, Paul Joyce   +2 more
wiley   +1 more source

Hypoglycemic agents and incidence of pancreatic cancer in diabetic patients: a meta-analysis

Frontiers in Pharmacology, 2023
Background and aims: Hypoglycemic agents are the primary therapeutic approach for the treatment of diabetes and have been postulated to impact pancreatic cancer (PC) incidence in diabetic patients.
Zimo Zhao, Xinyi He, Yan Sun
doaj   +1 more source

Trends in Drug Utilization, Glycemic Control, and Rates of Severe Hypoglycemia, 2006-2013. [PDF]

, 2016
ObjectiveTo examine temporal trends in utilization of glucose-lowering medications, glycemic control, and rate of severe hypoglycemia among patients with type 2 diabetes (T2DM).Research design and methodsUsing claims data from 1.66 million privately ...
Gill, Thomas M, Herrin, Jeph, Inzucchi, Silvio E, Krumholz, Harlan M, Lipska, Kasia J, McCoy, Rozalina G, Ross, Joseph S, Shah, Nilay D, Steinman, Michael A, Yao, Xiaoxi   +9 more
core   +1 more source

Thiazolidinediones and fluid retention [PDF]

Kidney International, 2007
CASE PRESENTATION A 67-year-old Caucasian woman was admitted to our hospital with progressive shortness of breath and swelling of all four extremities. Her past medical history included type 2 diabetes and hypertension of approximately 20 and 10 years of duration, respectively, hypothyroidism, morbid obesity, paroxysmal atrial fibrillation, and ...
Kiryluk, K., Isom, R.
openaire   +2 more sources

GLP‐1 Receptor Agonists in Metabolic Dysfunction‐Associated Steatotic Liver Disease: Bridging Hepatic and Cardiovascular Outcomes

Chronic Diseases and Translational Medicine, EarlyView.
Endogenous GLP‐1 and exogenous GLP‐1 RAs activate GLP‐1R‐expressing vagal afferents in the portal vein, projecting to the nucleus tractus solitarius (NTS). This input engages brainstem–hypothalamic circuits that regulate metabolic homeostasis. Hypothalamic efferent vagal output to the liver suppresses lipogenesis, enhances triglyceride export, and ...
Gabriel Amorim Moreira Alves, Masatoki Teranishi, Rajendranandini Majumdar, Fazal Khan, Mohan Dodeja, Ana Claudia Teixeira de Castro Gonçalves Ortega, Marco Acerboni, Arosh S. Perera Molligoda Arachchige, Frank James   +8 more
wiley   +1 more source