Activation and regioselectivity of five-membered cyclic thionocarbamates to nucleophilic attack [PDF]
, 2013 The cyclic thionocarbamate of alaninol undergoes nucleophilic attack by sulfur nucleophiles at 5-C to give 1-thiopropyl-2-amine derivatives when derivatised on nitrogen with a Boc group.
Awheda, I +3 more
core +1 more source
Condensation of 4-hydroxy-2-thiazolines with 1,2-phenylenediamine as a novel effective route to thiazolo[3,4-a]quinoxalines [PDF]
, 2004 Thiazolo[3,4-a]quinoxalin-4-ones were prepared in two steps starting from methyl phenylchloropyruvate using a new strategy for the construction of the ring system. A key step in this new method involves the reaction of 4-hydroxytetrahydrothiazoles with 1,
Gubaidullin, Aidar T +4 more
core +1 more source
Development of a Telescoped Flow Process for the Safe and Effective Generation of Propargylic Amines
Molecules, 2019 Propargylic amines are important multifunctional building blocks that are frequently exploited in the synthesis of privileged heterocyclic entities. Herein we report on a novel flow process that achieves the safe and effective on-demand synthesis of ...
Kian Donnelly +2 more
doaj +1 more source
2-Amino-1,3-thiazoline hydrochloride [PDF]
Acta Crystallographica Section B Structural Crystallography and Crystal Chemistry, 1981 C3H,N2S+. C1-2 M , = 138.62, monoclinic, P2,/c, a = 7.240 (7), b = 6.176 (2), c = 13.462 (8) A,8 = 100.10 (3)quot;, D, = 1.51, D, = 1.55 Mg m-3, Z =4, p = 7.619 mm-'. Final R = 0.110 for 657 observed reflections. The nonplanar thiazoline ring assumes an13; envelope conformation. The crystal structure is13; stabilized by NH . . .
B. M. Vedavathi, K. Vijayan
openaire +1 more source
A Unique Tryptophan C‐Prenyltransferase from the Kawaguchipeptin Biosynthetic Pathway [PDF]
, 2016 Acknowledgements This work was supported by funding of the Academy of Finland (259505), Helsinki University Research grant (490085) and ESCMID grant (4720572) to D.P.F., University of Pittsburgh Central Research Development Fund to X.L., Technology ...
Arnison +21 more
core +2 more sources
Bright Circularly Polarized Electrochemiluminescence from Heterobinuclear IrIII–AuI Enantiomers
Angewandte Chemie, Volume 138, Issue 1, 2 January 2026.Efficient and bright circularly polarized electrochemiluminescence (CP‐ECL) is achieved in a class of enantiopure hetobinuclear iridium(III)–gold(I) complexes owing to the combination of high ECL efficiency with stability, good emission dissymmetry factor and high brightness, thus paving the way to the next‐generation of bright CP‐ECL probes.
Lavinia Ballerini +13 more
wiley +2 more sources
Pyrimidin‐/Thiazol‐/Thiazolin‐ylidenamidothiophosphoric Dichlorides.
ChemInform, 2003 AbstractFor Abstract see ChemInform Abstract in Full Text.
Vijaya Kabra +3 more
openaire +1 more source
A facile, inexpensive scalable route to α-methyl cysteine [PDF]
, 2013 A facile, scalable synthesis of α-methyl cysteine with three alternate thiol protecting groups (Trt, Allyl and tBu) is described. The thiol protected amino acids are obtained in 6 steps from L-cysteine ethyl ester and are ideally suited for a range of ...
Hulme, Alison N, Johnston, Heather J
core +1 more source
The effects of O-GlcNAc alteration on Alzheimer-like neurodegeneration in SK-N-SH cells
Biomedical Papers, 2018 Background: O-GlcNAcylation is a highly dynamic post-translational modification that plays a key role in regulating phosphorylation of protein and cell survival.
Nan Ding +6 more
doaj +1 more source
O-GlcNAcase Fragment Discovery with Fluorescence Polarimetry [PDF]
, 2018 The attachment of the sugar N-acetyl-D-glucosamine (GlcNAc) to specific serine and threonine residues on proteins is referred to as protein O-GlcNAcylation.
Aristotelous, Tonia +6 more
core +3 more sources