Results 41 to 50 of about 2,247 (174)

Watasemycin biosynthesis in Streptomyces venezuelae : thiazoline C-methylation by a type B radical-SAM methylase homologue [PDF]

, 2017
2-Hydroxyphenylthiazolines are a family of iron-chelating nonribosomal peptide natural products that function as virulence-conferring siderophores in various Gram-negative bacteria.
Al-Bassam, Mahmoud M., Bibb, Maureen J., Bibb, Mervyn J., Challis, Gregory L., Inahashi, Yuki, Song, Lijiang, Zhou, Shanshan   +6 more
core   +1 more source

Synthesis of Polysubstituted Tetrahydro‐1,4‐Thiazepines by Rhodium‐Catalyzed Ring Expansion of Dihydro‐1,3‐Thiazines with Diazoesters

Advanced Synthesis &Catalysis, Volume 368, Issue 2, January 2026.
A rhodium(II)‐catalyzed ring expansion of stereodefined dihydro‐1,3‐thiazines with diazomalonates gives 1,4‐thiazepines via a sulfonium ylide rearrangement. The reaction shows a cis/trans reactivity divergence arising from different metal coordination, as revealed by experiments and density functional theory studies.
Laurine Tual, Romain Pertschi, Gaëlle Blond, Mihaela Gulea   +3 more
wiley   +1 more source

Scientific Opinion on Flavouring Group Evaluation 21, Revision 4 (FGE.21Rev4): Thiazoles, thiophenes, thiazoline and thienyl derivatives from chemical groups 29 and 30

EFSA Journal, 2013
The Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids of the European Food Safety Authority was requested to evaluate 59 flavouring substances in the Flavouring Group Evaluation 21, Revision 4, using the Procedure in Commission ...
EFSA Panel on Food Contact Materials, Enzymes, Flavourings and Processing Aids (CEF)
doaj   +1 more source

Nixtamalization of a Yellow Maize Snack: Product Evaluation Using Different Sensory Evaluation Methods

Journal of Food Processing and Preservation, Volume 2026, Issue 1, 2026.
Yellow maize is cultivated by small‐scale farmers in South Africa, solely for animal consumption, due to cultural preferences of white maize as a staple, while it holds untapped value in addressing household food insecurity if redirected for human consumption. This study is aimed at evaluating a consumer‐acceptable yellow maize snack product.
Faith Matiza Ruzengwe, Sandile F. Moagi, Carina Bothma, Jana Vermaas, Alba du Toit, Poulami Jha   +5 more
wiley   +1 more source

Analysis of transition state mimicry by tight binding aminothiazoline inhibitors provides insight into catalysis by human : O-GlcNAcase [PDF]

, 2016
The modification of nucleocytoplasmic proteins with O-linked N-Acetylglucosamine (O-GlcNAc) plays diverse roles in multicellular organisms. Inhibitors of O-GlcNAc hydrolase (OGA), the enzyme that removes O-GlcNAc from proteins, lead to increased O-GlcNAc
Avalos Gonzalez, Bartlett, Beer, Borghgraef, Cetinbas, Copeland, Dennis, Dorfmueller, Dorfmueller, Dorfmueller, Ferrer, Gao, Graham, Greig, Haltiwanger, Hart, Khidekel, Kim, Kim, Kreppel, Kuntz, Kuzmic, Liu, Liu, Lombard, Lubas, Ma, Macauley, Macauley, Macauley, Macauley, Macauley, Mader, Mark, Mehdy, Morrison, Mosi, Murphy, Ortiz-Meoz, Ozcan, Perrin, Ranuncolo, Rao, Roeser, Ruan, Stubbs, Torres, Trinidad, Wang, Whelan, Whitworth, Yi, Yuzwa, Yuzwa, Yuzwa, Yuzwa, Zhu   +56 more
core   +1 more source

Thiopeptide antibiotics: retrospective and recent advances [PDF]

, 2014
Thiopeptides, or thiazolyl peptides, are a relatively new family of antibiotics that already counts with more than one hundred different entities.
Albericio Palomera, Fernando, Just Baringo, Xavier, Álvarez Domingo, Mercedes   +2 more
core   +3 more sources

Recent Advances in Isatin–Thiazole Hybrids: Synthesis, Structural Design, and Biological Application

Chemistry &Biodiversity, Volume 22, Issue 12, December 2025.
ABSTRACT Isatin–thiazole hybrids are considered privileged chemical scaffolds due to their broad spectrum of pharmacological properties, making them attractive candidates for drug development. As a result, isatin–thiazole derivatives have emerged as a prominent class of hybrid heterocycles and have been the focus of extensive research in recent years ...
Isadora M. G. Andrade, Edson de O. Lima Filho, Caio F. Valadão, Luana da S. M. Forezi, Fernando de C. da Silva   +4 more
wiley   +1 more source

Chitinase Inhibition by Chitobiose and Chitotriose Thiazolines

Angewandte Chemie International Edition, 2010
A good imitation: Di- and trisaccharide analogues of the oxazoline intermediate formed during enzymatic hydrolysis of chitin were found to be potent inhibitors of chitinase A. The high affinity and enzymatic stability of a readily synthesized thioamide trisaccharide (two molecules of which are shown in the enzyme active site), and the mechanism-based ...
James M. Macdonald, Chris A. Tarling, Edward Taylor, Rebecca J. Dennis, David S. Myers, Spencer Knapp, Gideon J. Davies, Stephen G. Withers   +7 more
openaire   +2 more sources

Enantioselective reduction of sulfur-containing cyclic imines through biocatalysis [PDF]

, 2018
Zumbrägel N, Merten C, Huber SM, Gröger H. Enantioselective reduction of sulfur-containing cyclic imines through biocatalysis. Nature Communications.
Gröger, Harald, Huber, Stefan M., Merten, Christian, Zumbrägel, Nadine   +3 more
core   +2 more sources

Protein O‐GlcNAcylation in Health and Diseases

MedComm, Volume 6, Issue 12, December 2025.
We first introduced the beneficial effects of normal protein O‐GlcNAcylation on health, impacting biological processes such as gene expression, cell cycle progression, metabolism, and signal transduction. Next, we described the role of abnormal protein O‐GlcNAcylation in the development and progression of diseases, including neurodegenerative diseases,
Zhihong Ran, Chuanbao Chen, Jingfeng Ou, Guanyi Wu, Chao Yang, Xiaoyou Liu   +5 more
wiley   +1 more source