Results 51 to 60 of about 2,247 (174)
Cyanobactins : ribosomally synthesized and post-translationally modified peptides produced by cyanobacteria [PDF]
, 2013 Ribosomal peptides are produced through the post-translational modification of precursor peptides. Cyanobactins are a family of ribosomal peptides produced by cyanobacteria.
Leikoski, Niina
core
Flavour Chemistry of Chicken Meat: A Review [PDF]
, 2013 Flavour comprises mainly of taste and aroma and is involved in consumers’ meat-buying behavior and preferences. Chicken meat flavour is supposed to be affected by a number of ante- and post-mortem factors, including breed, diet, post-mortem ageing ...
Ahn, Dong +4 more
core +3 more sources
Chemical Biology &Drug Design, Volume 106, Issue 6, December 2025.We demonstrated the application of molecular hybridization in disclosing new pyrimidine‐thiazole molecular hybrids as potential α‐glucosidase and α‐amylase inhibitors and antioxidant agents. The representative compound of the series exhibited 3‐fold more potency than the standard drug acarbose against α‐glucosidase and 2‐fold greater potency than ...
Gobind Kumar +8 more
wiley +1 more source
ThiF‐Like Enzyme Chemistry in Primary and Secondary Metabolism
ChemBioChem, Volume 26, Issue 21, November 8, 2025.ThiF‐like enzymes are a widespread protein family found in disparate biosynthetic pathways. They are unified by their use of an NTP to modify a carboxylate, generating an activated species prone to nucleophilic addition. This common intermediate is then targeted by diverse nucleophiles, including persulfide or amino acid side chains, to yield a variety
Keelie S. Butler +2 more
wiley +1 more source
ChemistryOpen, Volume 14, Issue 11, November 2025.Novel benzimidazothiazole–thiazole hybrids are synthesized and evaluated for anticancer activity against HCT‐116 colon cancer cells. Compound 16b shows superior cytotoxicity over doxorubicin. Molecular docking confirms strong binding to 6MTU protein, and ADMET profiling indicates favorable pharmacokinetics and low toxicity.
Bader Huwaimel +6 more
wiley +1 more source
Advanced Synthesis &Catalysis, Volume 367, Issue 18, September 29, 2025.Enantioenriched α‐/β‐/γ‐thiocarboxylic acids featuring C–S chirality are valuable targets in organic synthesis. This review outlines recent progress in their asymmetric synthesis, including chiral pool approaches, metal‐ /organo‐catalysis, and emerging biocatalytic strategies. Enantiomerically pure α‐/β‐/γ‐thiocarboxylic acids bearing a stereocentre at
Jingyue Wu, Daniele Castagnolo
wiley +1 more source
Investigating the Intercarbonyl X...C' (X=O/S/N) Interactions in Short Peptides and Peptidomimetics. Evidence of charge->II* Interactions. Synthesis and Characterization of Thioimidate Isostere Containing Peptidomimetics [PDF]
, 2016 This thesis entitled “Investigating the Intercarbonyl X···C′ (X = O/S/N) Interactions in Short Peptides and Peptidomimetics. Evidence of Charge→π* Interactions. Synthesis and Characterization of Thioimidate Isostere Containing Peptidomimetics” is divided
Tumminakatti, Shama
core +1 more source
Bilayer Paper‐Gelatin Films With Modified Curcumin for Sustainable Packaging Applications
Polymers for Advanced Technologies, Volume 36, Issue 9, September 2025.ABSTRACT Paper is a sustainable, cost‐effective, and versatile material broadly used in packaging applications. However, this material has poor barrier properties to water and oxygen, as well as high water sensitivity, limiting its food packaging application.
Kennya Thayres dos Santos Lima +3 more
wiley +1 more source
Electrostatic potential as a reactivity scoring function in computer‐assisted enzyme engineering
The FEBS Journal, Volume 292, Issue 16, Page 4211-4231, August 2025.We present a computational metric that quantifies the electrostatic complementarity of enzymes to the charge distribution of substrates at the transition state. Implemented in BindScan, this metric accurately predicts functionally relevant mutations in glycoside hydrolases.
Aitor Vega, Antoni Planas, Xevi Biarnés
wiley +1 more source
A novel prohibitin-binding compound induces the mitochondrial apoptotic pathway through NOXA and BIM upregulation [PDF]
, 2016 We previously described diaryl trifluorothiazoline compound 1a (hereafter referred to as fluorizoline) as a first-in-class small molecule that induces p53-independent apoptosis in a wide range of tumor cell lines.
Albericio Palomera, Fernando +15 more
core +1 more source