Results 31 to 40 of about 733,949 (305)

Development and Application of 200 mm Extra Thick 12Cr2MolR Steel Plate for Hydrogen Chemical Industry

open access: yesTeshugang, 2020
According to the requirements of 200 mm extra thick 12Cr2MolR steel plate for hydrogen chemical industry i. e.P ≤0.007% ,Si≤0. 1% , brittleness index J≤100X≤10x10-6by the electroslag remelting technology of 120 t BOF-LF-VD-continuous bloom and the heat ...
尹卫江   +6 more
doaj  

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Simplified Procedure For The Free Vibration Analysis Of Rectangular Plate Structures With Holes And Stiffeners

open access: yesPolish Maritime Research, 2015
Thin and thick plates, plates with holes, stiffened panels and stiffened panels with holes are primary structural members in almost all fields of engineering: civil, mechanical, aerospace, naval, ocean etc. In this paper, a simple and efficient procedure
Cho Dae Seung   +2 more
doaj   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

Analysis of damage behavior of new-type marine composite thick plate with reinforcing ribs and core material in middle

open access: yesZhongguo Jianchuan Yanjiu
ObjectivesTo solve the problem of applying thick carbon fiber laminates in naval architecture and marine engineering, this paper proposes a thick plate structure composed of thin carbon fiber laminates with reinforcing ribs and core material in the ...
Hao TONG, Yuchao YUAN, Wenyong TANG
doaj   +1 more source

A comparison between single sided and double sided friction stir welded 8mm thick DH36 steel plate [PDF]

open access: yes, 2012
As part of an ongoing process to fully evaluate the potential for friction stir welding (FSW) to be used in the shipbuilding industry, a comparison has been made between two variants of the process.
Cater, Stephen R.   +3 more
core  

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

A new finite element formulation for vibration analysis of thick plates

open access: yesInternational Journal of Naval Architecture and Ocean Engineering, 2015
A new procedure for determining properties of thick plate finite elements, based on the modified Mindlin theory for moderately thick plate, is presented.
Ivo Senjanović   +2 more
doaj   +1 more source

Accurate Numerical Solutions for Standard Skew Plate Benchmark Problems

open access: yesZbornik Radova, 2022
Morley’s skew plate and Razzaque’s skew plate are two standard benchmark problems used for the performance evaluation of plate finite elements. The reference solutions for these problems are given for the thin plate case only, and various plate finite ...
Marin Grbac, Dragan Ribarić
doaj   +1 more source

PERENCANAAN ULANG GEDUNG RUSUNAWA BLOK A UNIVERSITAS MUHAMMADIYAH MALANG MENGGUNAKAN KOMPOSIT BAJA DENGAN METODE LRFD [PDF]

open access: yes, 2009
House is human essential requirement, in growth of mansions become answers to problem limitation of farm. Mansions including high building structure which is planning of research require to laboring burden.
RUMATIGA, FATHUR RAHMAN
core  

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