Results 1 to 10 of about 1,360 (195)
In vitro activity of N-formimidoyl thienamycin (MK0787), a crystalline derivative of thienamycin [PDF]
Antimicrobial Agents and Chemotherapy, 1980 N-Formimidoyl thienamycin (MK0787) is a derivative of thienamycin, a unique, new beta-lactam antibiotic. Its activity against 285 aerobic and facultatively anaerobic clinical isolates was compared with the activities of cephalothin, ampicillin, penicillin G, ticarcillin, and tobramycin.
V W, Horadam +3 more
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Antibacterial activities of a new stabilized thienamycin, N-formimidoyl thienamycin, in comparison with other antibiotics [PDF]
Antimicrobial Agents and Chemotherapy, 1980 The in vitro activity of a new crystalline derivative of thienamycin, N-formimidoyl thienamycin (MK0787), was tested against 46 laboratory reference strains and 2,158 clinical isolates of gram-positive and -negative bacteria, including anaerobes, and compared with cefoxitin, cefaxolin, carbenicillin, and amikacin.
T, Kesado, T, Hashizume, Y, Asahi
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N-formimidoyl thienamycin (MK0787): in vitro study [PDF]
Antimicrobial Agents and Chemotherapy, 1981 N-Formimidoyl thienamycin (MK0787) was compared in vitro with three other beta-lactam and two aminoglycoside antibiotics. It was second in activity only to cefotaxime against members of the Enterobacteriaceae and to amikacin against Pseudomonas species. It was the most active antibiotic against Staphylococcus aureus.
S, Shadomy, R S, May
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First Asymmetric Synthesis of (+)-Thienamycin [PDF]
Synfacts, 2022 Dirk Trauner, Matthew DiCairano
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Synthesis of Thienamycin and Related Compounds
HETEROCYCLES, 1980 Tetsuji Kametani +5 more
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A Formal Total Synthesis of Thienamycin
HETEROCYCLES, 1979 Tetsuji Kametani +4 more
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Asymmetric Synthesis of (+)-Thienamycin
HETEROCYCLES, 1983 Shiro Ikegami +2 more
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In Vitro Activity of Thienamycin [PDF]
Antimicrobial Agents and Chemotherapy, 1978 The in vitro activity of thienamycin was tested against 135 aerobic and anaerobic bacteria. The compound was highly active against resistant gram-negative bacilli and penicillin-resistant Straphylococcus aureus . The antianaerobic spectrum of the drug seemed to be comparable to that of metronidazole.
F P, Tally, N V, Jacobus, S L, Gorbach
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An Alternative Total Synthesis of (±)-Thienamycin
HETEROCYCLES, 1980 Tetsuji Kametani +3 more
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Synthese einer chiralen Thienamycin-Vorstufe / Synthesis of a Chiral Thienamycine Intermediate [PDF]
Zeitschrift für Naturforschung B, 1987 Abstract A key intermediate of Kametani’s total synthesis of racemic thienamycine has now been prepared in chiral form via a 1.3-dipolar cycloadduct of a chiral nitrone and benzyl crotonate.
Hubert Martin, Rudolf Herrmann, Ivar Ugi
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