Results 111 to 120 of about 910 (153)

Implant-associated ESBL-Klebsiella pneumonia producing small colony variant bone and joint infection in a healthy 40-year-old man. [PDF]

BMJ Case Rep, 2017
Ronde-Oustau C, Lustig S, Dupieux C, Ferry T, Lyon BJI Study group.   +4 more
europepmc   +1 more source

Synthese neuer Carbapenem-Antibiotika [PDF]

, 2008
Schlaf, Susanne
core  

Synthesis of carbapenams from pyrroles [PDF]

Ottaway, Carol Jean
core   +1 more source

Approaches to the synthesis of phosphorus analogues of the beta-lactam antibiotics. [PDF]

, 1982
Mickel, Stuart J.
core  

Some of the next articles are maybe not open access.

Related searches:

Formal synthesis of Thienamycin

The Journal of Antibiotics, 2017
A formal synthesis of Thienamycin from ethyl (E)-crotonate and a cyclic five-membered nitrone derived from 2-deoxy-d-ribose is described. The synthesis involves 1,3-dipolar cycloaddition, cleavage of the N-O bond in the adduct, and intramolecular N-acylation to afford a bicyclic carbapenam skeleton.
Michał, Pieczykolan, Bartłomiej, Furman, Marek, Chmielewski   +2 more
openaire   +2 more sources

Thienamycin: development of imipenem-cilastatin

Journal of Antimicrobial Chemotherapy, 1983
Thienamycin, a natural product produced by Streptomyces cattleya is the first representative of a unique class of beta-lactam antibiotics, the carbapenems. Despite its outstanding potency and antibacterial spectrum, thienamycin was itself unsuited for further development because of its chemical instability in concentrated solution and in the solid ...
F M, Kahan, H, Kropp, J G, Sundelof, J, Birnbaum   +3 more
openaire   +2 more sources

ChemInform Abstract: THIENAMYCIN TOTAL SYNTHESIS. 3. TOTAL SYNTHESIS OF (.+‐.)‐THIENAMYCIN AND (.+‐.)‐8‐EPITHIENAMYCIN

Chemischer Informationsdienst, 1980
AbstractAus dem früher aufgeführten sterisch definierten Azetidinon‐carbinol (I) entsteht der Aldehyd (II), der in das Dithioacetal (III) übergeführt wird und zu (IVa) eliminiert.
S. M. SCHMITT, D. B. R. JOHNSTON, B. G. CHRISTENSEN   +2 more
openaire   +1 more source

Thienamycin-imipenem

2000
Abstract Despite the outstanding antibacterial profile of thienamycin 1, this compound was not considered attractive for clinical use because of its high chemical instability, found to be both pH- and concentration-dependent.4.
Walter Cabri, Romano Di Fabio
openaire   +1 more source

A practical synthesis of (±)-thienamycin

Tetrahedron Letters, 1980
Abstract An efficient and operationally simple synthesis of (±)-thienamycin is described.
D.G. Melillo, I. Shinkai, T. Liu, K. Ryan, M. Sletzinger   +4 more
openaire   +1 more source