Results 81 to 90 of about 1,779,309 (215)

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

The Analysis of Students' Mathematical Critical Thinking Skills Solving HOTS-Based Problems

Tarbawi
s The rapid development of technology in the digital era demands the readiness of students to compete and face various problems that arise. This requires critical thinking skills in formulating problems, finding solutions, and determining the resolution ...
Dini Palupi Putri, Luís Miguel Oliveira de Barros Cardoso, Fevi Rahmadeni, Putri Wahyuni, Paidi Gusmuliana   +4 more
doaj   +5 more sources

Critical thinking skills of natural science undergraduate students on biology subject: Gender perspective

JPBI (Jurnal Pendidikan Biologi Indonesia), 2020
One of the most important skills needed to face the 21st-century challenges is critical thinking. Gender differences are considered to contribute to the critical thinking skills.
Nur Hayati, Nindha Ayu Berlianti
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Teaching and Learning in Interdisciplinary Higher Education: A Systematic Review [PDF]

, 2009
Interdisciplinary higher education aims to develop boundary-crossing skills, such as interdisciplinary thinking. In the present review study, interdisciplinary thinking was defined as the capacity to integrate knowledge of two or more disciplines to ...
Biemans, H., Luning, P.A., Mulder, M., Spelt, E.J.H., Tobi, H.   +4 more
core   +2 more sources

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

FEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

A comprehensive approach to the development of thinking skills

Koers : Bulletin for Christian Scholarship, 1995
The development of independent and innovative thinking entails much more than merely the acquisition of a series of thinking skills. A comprehensive approach based upon inter-disciplinary cooperation between, among others, the disciplines of philosophy ...
G. J. Rossouw, J. C. Lamprecht
doaj   +1 more source

Editorial: Thinking Skills [PDF]

Philosophy, 2000
Editorial: Thinking SkillsThe Government is, it seems, keen to introduce ‘thinking skills’ into the curriculum. Of course, no one could be against people, young or old, thinking. Nor would it be appropriate in a philosophical journal to cast doubt on an initiative that might expand the market for philosophers.
openaire   +1 more source

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source