Toxicological Profile of the Pain-Relieving Antioxidant Compound Thioctic Acid in Its Racemic and Enantiomeric Forms [PDF]
Antioxidants, 2020 Thioctic acid is a multipotent antioxidant compound existing as dextrorotatory (+), eutomer and naturally occurring and levorotatory (−). It has been proven to help fight many pathologies and is sold as racemate.
Elena Lucarini +6 more
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Thioctic Acid Derivatives as Building Blocks to Incorporate DNA Oligonucleotides onto Gold Nanoparticles [PDF]
Molecules, 2014 Oligonucleotide gold nanoparticle conjugates are being used as diagnostic tools and gene silencing experiments. Thiol-chemistry is mostly used to functionalize gold nanoparticles with oligonucleotides and to incorporate DNA or RNA molecules onto gold ...
Sónia Pérez-Rentero +4 more
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Beneficial effects of vincamine with thioctic acid and lutein on retinal and optic nerve functions in an opaque media [PDF]
International Journal of Ophthalmology, 2019 AIM: To detect whether the combination of vincamine, thioctic acid and lutein will improve the retina and optic nerve functions in cases of an opaque media with an optic nerve and/or a retinal defect or not. METHODS: Totally 2000 patients (2000 eyes) of
Mona Abdelkader +4 more
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Synergistic antiallodynic effects of pregabalin and thioctic acid in a rat model of neuropathic pain [PDF]
Frontiers in PharmacologyBackgroundNeuropathic pain is a chronic and often disabling condition that remains refractory to monotherapy because of limited efficacy and dose-limiting adverse effects.
Edith Zárate +3 more
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Protective effects of the R-(+)-thioctic acid treatment: possible anti-inflammatory activity on heart of hypertensive rats [PDF]
BMC Complementary Medicine and TherapiesBackground In cardiovascular disease, high blood pressure is associated with oxidative stress, promoting endothelial dysfunction, vascular remodeling, and inflammation. Clinical trials are discordant that the most effective treatment in the management of
Proshanta Roy +6 more
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Thioctic acid shield against lipopolysaccharide depression and endoplasmic reticulum stress: GR7M/Homer/ATF6 signaling [PDF]
Future Science OAAim: Endoplasmic reticulum stress triggers neuronal unfolded protein accumulation, contributing to the pathophysiology of depression psychiatric illnesses.Materials & methods: The brain-derived neurotrophic factor (BDNF), metabotropic glutamate receptor ...
Mai O. Kadry, Rehab M. Abdel-Megeed
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Nucleoside conjugates of quantum dots for characterization of G protein-coupled receptors: strategies for immobilizing A2A adenosine receptor agonists [PDF]
Journal of Nanobiotechnology, 2010 Background Quantum dots (QDs) are crystalline nanoparticles that are compatible with biological systems to provide a chemically and photochemically stable fluorescent label.
Gao Zhan-Guo +5 more
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Bio‐Based Thermoplastic Room Temperature Phosphorescent Materials with Closed‐Loop Recyclability [PDF]
Advanced ScienceProducing thermoplastic room temperature phosphorescent (RTP) materials with closed‐loop recyclability from natural sources is an attractive approach but hard to achieve.
Yuanyuan Qian +7 more
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Exosome-loaded tannic acid–thioctic acid hydrogel enhances wound healing in coagulation disorders [PDF]
Materials Today BioHemophilia poses distinct challenges to wound healing, primarily due to uncontrolled bleeding and delayed tissue repair. This study explored a novel tannic acid-thioctic acid (TATA) hydrogel, enriched with exosomes derived from bone marrow mesenchymal ...
Yuesheng Tu +12 more
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Robust and Reversible Supramolecular Adhesive via Dynamic Covalent Bond Crosslinking‐Induced Assembly of Metal‐Coordinated Nanoparticles [PDF]
Advanced ScienceSupramolecular adhesives, praised for their stimuli‐responsiveness and reversibility, have gained significant attention. However, most of these adhesives demonstrate low tolerance to extreme environments and exhibit diminished adhesion performance after ...
Yanyan Guo +3 more
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