Critical appraisal of the use of alpha lipoic acid (thioctic acid) in the treatment of symptomatic diabetic polyneuropathy [PDF]
Therapeutics and Clinical Risk Management, 2011 Courtney E McIlduff, Seward B RutkoveDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USABackground: The most common of the neuropathies associated with diabetes mellitus, diabetic sensorimotor polyneuropathy (DSPN) is a ...
McIlduff CE, Rutkove SB
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Comparative Dissolution Kinetics of Several Multisource Thioctic Acid Products [PDF]
Регуляторные исследования и экспертиза лекарственных средств, 2022 The relationship between dissolution and bioavailability is an example of the interdependency between the quality of a medicinal product and its safety and efficacy.
G. F. Vasilenko +6 more
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Efficacy of combined topiramate/thioctic acid therapy in migraine prophylaxis [PDF]
Saudi Pharmaceutical Journal, 2010 Migraine cannot be cured and the aim, shared with the patient, is to minimise the impact of the illness on the patient’s life and lifestyle. The aim of prophylaxis is to reduce the number of migraine attacks.
Ali AM, Awad TG, Al-Adl NM.
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Research of physico-chemical and technological properties of thioctic acid
Фармацевтичний журнал, 2018 Characteristics and relevance of article topic. Analysis of the literature data shows that the thioctic acid preparations are widely used in the treatment of various diseases.
I. V. Kovalevska, O. A. Ruban
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INVESTIGATION OF THE PHARMACO-TECHNOLOGICAL PROPERTIES OF SOLID DISPERSIONS OF THIOCTIC ACID, OBTAINED BY MICRONIZATION [PDF]
Annals of Mechnikov's Institute, 2018 Introduction. Thioctic acid is used in the treatment of diseases that are characterized by lack of mitochondrial activity, which is responsible for the formation of free radicals. Widespread use of thioctic acid is due to the chemical structure.
Kovalevska, I. V., Ruban, O. A.
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Comparative Assessment of the Activity of Racemic and Dextrorotatory Forms of Thioctic (Alpha-Lipoic) Acid in Low Back Pain: Preclinical Results and Clinical Evidences From an Open Randomized Trial [PDF]
Frontiers in Pharmacology, 2021 Peripheral neuropathies, characterized by altered nociceptive and muscular functions, are related to oxidative stress. Thioctic acid is a natural antioxidant existing as two optical isomers, but most clinically used as racemic mixture.
Alessandra Pacini +7 more
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The role of information service in rational pharmacotherapy with thioctic acid in patients in Preferential Medicinal Providing [PDF]
Качественная клиническая практика, 2021 Rational pharmacotherapy in the Program of Preferential Medicinal Providing can be implemented subject to high-quality information support from healthcare professionals.
E. V. Eliseeva +4 more
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Brain Activity of Thioctic Acid Enantiomers: In Vitro and in Vivo Studies in an Animal Model of Cerebrovascular Injury [PDF]
International Journal of Molecular Sciences, 2013 Oxidative stress is an imbalance between the production of free radicals and antioxidant defense mechanisms, potentially leading to tissue damage. Oxidative stress has a key role in the development of cerebrovascular and/or neurodegenerative diseases ...
Lorenzo di Cesare Mannelli +2 more
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Spectrophotometric determination of thioctic (a-Aipoic) acid in water and pharmaceutical preparations [PDF]
Journal of the Serbian Chemical Society, 2007 A spectrophotometric method is described for the assay of thioctic acid. The method is based on the reaction between the drug and palladium(II) chloride.
ZAGORKA KORICANAC +3 more
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Experience of the use of drugs with thioctic acid in overweight women using combined oral contraceptives [PDF]
Zaporožskij Medicinskij Žurnal, 2014 Introduction Overweight is a serious medical, social and economic problem of the modern society. Today it is established that the level of sexual activity in women is not dependent on the body mass index.
N. V. Avramenko +3 more
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