Comparative Dissolution Kinetics of Several Multisource Thioctic Acid Products [PDF]
The relationship between dissolution and bioavailability is an example of the interdependency between the quality of a medicinal product and its safety and efficacy.
G. F. Vasilenko +6 more
doaj +2 more sources
Brain Activity of Thioctic Acid Enantiomers: In Vitro and in Vivo Studies in an Animal Model of Cerebrovascular Injury [PDF]
Oxidative stress is an imbalance between the production of free radicals and antioxidant defense mechanisms, potentially leading to tissue damage. Oxidative stress has a key role in the development of cerebrovascular and/or neurodegenerative diseases ...
Lorenzo Di Cesare Mannelli +2 more
exaly +3 more sources
Research of physico-chemical and technological properties of thioctic acid
Characteristics and relevance of article topic. Analysis of the literature data shows that the thioctic acid preparations are widely used in the treatment of various diseases.
I. V. Kovalevska, O. A. Ruban
doaj +2 more sources
INVESTIGATION OF THE PHARMACO-TECHNOLOGICAL PROPERTIES OF SOLID DISPERSIONS OF THIOCTIC ACID, OBTAINED BY MICRONIZATION [PDF]
Introduction. Thioctic acid is used in the treatment of diseases that are characterized by lack of mitochondrial activity, which is responsible for the formation of free radicals. Widespread use of thioctic acid is due to the chemical structure.
Kovalevska, I. V., Ruban, O. A.
doaj +2 more sources
The role of information service in rational pharmacotherapy with thioctic acid in patients in Preferential Medicinal Providing [PDF]
Rational pharmacotherapy in the Program of Preferential Medicinal Providing can be implemented subject to high-quality information support from healthcare professionals.
E. V. Eliseeva +4 more
doaj +2 more sources
Purpose: to assess the possibility of using thioctic acid and indomethacin tin eyedrops for the therapy of early stages of retinal neurodegeneration.Material and methods.
V. V. Neroev +5 more
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Spectrophotometric determination of thioctic (a-Aipoic) acid in water and pharmaceutical preparations [PDF]
A spectrophotometric method is described for the assay of thioctic acid. The method is based on the reaction between the drug and palladium(II) chloride.
ZAGORKA KORICANAC +3 more
doaj +1 more source
Experience of the use of drugs with thioctic acid in overweight women using combined oral contraceptives [PDF]
Introduction Overweight is a serious medical, social and economic problem of the modern society. Today it is established that the level of sexual activity in women is not dependent on the body mass index.
N. V. Avramenko +3 more
doaj +2 more sources
Effectiveness of thioctic acid drugs (Espa-lipon) in the treatment of diabetic polyneuropathy
This article tells about the treatment of diabetic polyneuropathy - the most common neurological complications of diabetes mellitus. The pathogenesis, diagnosis and current evidence-based treatments are described. Thioctic acid drugs for the treatment of
M. V. Nesterova, V. V. Galkin
doaj +2 more sources
To evaluate the effect and toxicity of alprostadil combined with thioctic acid injection in the treatment of patients with diabetic nephropathy (DN).
Hong Yan +5 more
doaj +2 more sources

