Effectiveness of thioctic acid drugs (Espa-lipon) in the treatment of diabetic polyneuropathy
This article tells about the treatment of diabetic polyneuropathy - the most common neurological complications of diabetes mellitus. The pathogenesis, diagnosis and current evidence-based treatments are described. Thioctic acid drugs for the treatment of
M. V. Nesterova, V. V. Galkin
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Hydrolytic stress degradation study and concomitant HPTLC estimation of thioctic acid and biotin in their combined capsules: greenness, blueness and whiteness assessment. [PDF]
El-Kafrawy DS, Abo-Gharam AH.
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R(+)-Thioctic Acid Effects on Oxidative Stress and Peripheral Neuropathy in Type II Diabetic Patients: Preliminary Results by Electron Paramagnetic Resonance and Electroneurography. [PDF]
Mrakic-Sposta S +8 more
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Peripheral neuropathies, characterized by altered nociceptive and muscular functions, are related to oxidative stress. Thioctic acid is a natural antioxidant existing as two optical isomers, but most clinically used as racemic mixture.
Alessandra Pacini +7 more
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Protective Effect of Thioctic Acid on Renal Ischemia-reperfusion Injury in Rat.
Ahmadvand H, Mahdavifard S.
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Salt-mediated self-assembly of thioctic acid on gold nanoparticles. [PDF]
Volkert AA +4 more
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Rational pharmacotherapy in the Program of Preferential Medicinal Providing can be implemented subject to high-quality information support from healthcare professionals.
E. V. Eliseeva +4 more
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INVESTIGATION OF THE PHARMACO-TECHNOLOGICAL PROPERTIES OF SOLID DISPERSIONS OF THIOCTIC ACID, OBTAINED BY MICRONIZATION [PDF]
Introduction. Thioctic acid is used in the treatment of diseases that are characterized by lack of mitochondrial activity, which is responsible for the formation of free radicals. Widespread use of thioctic acid is due to the chemical structure.
Kovalevska, I. V., Ruban, O. A.
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Spectrophotometric determination of thioctic (α-lipoic) acid in water and pharmaceutical preparations [PDF]
A spectrophotometric method is described for the assay of thioctic acid. The method is based on the reaction between the drug and palladium(II) chloride.
Korićanac Zagorka +3 more
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Effects of stereoisomers of thioctic acid on rat renal vasculature microanatomy [PDF]
Metabolism of oxygen by cells can generate potentially dangerous reactive oxygen species (ROS). Endothelial cells lining vascular luminal surface are an important site of signalling molecules and a ROS target during ischemia, inflammation and other ...
AMENTA, Francesco +4 more
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