Purpose: to assess the possibility of using thioctic acid and indomethacin tin eyedrops for the therapy of early stages of retinal neurodegeneration.Material and methods.
V. V. Neroev +5 more
doaj +2 more sources
Modern Approaches to the Technology of Tablet Dosage Forms of Thioctic Acid (Review)
Introduction. Thioctic (α-lipoic) acid is an endogenous antioxidant and is used for liver diseases, poisoning with salts of heavy metals, hyperlipidemia, atherosclerotic heart disease, neuropathy, insulin-resistant forms of diabetes mellitus, etc ...
S. N. Egorova +4 more
doaj +1 more source
Neuroprotective activity of thioctic acid in central nervous system lesions consequent to peripheral nerve injury. [PDF]
Peripheral neuropathies are heterogeneous disorders presenting often with hyperalgesia and allodynia. This study has assessed if chronic constriction injury (CCI) of sciatic nerve is accompanied by increased oxidative stress and central nervous system ...
Tomassoni D +6 more
europepmc +2 more sources
Self-Assembly of Organic-Inorganic Copolymers Toward Bio-Inspired Cementitious Composites. [PDF]
Organic–inorganic copolymerization of calcium silicate hydrate and thioctic acid produces a self‐organized nanocomposite inspired by the disordered collagen–mineral architecture of trabecular bone. The resulting material combines a compressive strength above 300 MPa with intrinsic physical reprocessibility, retaining over 80% of its strength and energy
Xie Z +8 more
europepmc +2 more sources
Use of thioctic acid in complex treatment of acute alcoholic pancreatitis [PDF]
The results of treatment of 27 patients with confirmed. acute alcoholic pancreatitis are studied. It is shown that application of thioctic acid in a dose of 600 mg in a day allows to localize process and to turn it on an aseptic way.
M. S. Funygin, D. B. Demin
doaj +1 more source
Salt-Mediated Self-Assembly of Thioctic Acid on Gold Nanoparticles [PDF]
Amanda Haes, Amanda M Goodman
exaly +2 more sources
Unveiling the Demographics and Clinical Characteristics of Diabetic Neuropathy: Findings From the National Health Insurance Service, 2012-2017. [PDF]
Diabetic neuropathy prevalence declined from 23.4% to 21.5% between 2012 and 2017. About half received treatment, mainly α‐lipoic acid monotherapy; patients were older with comorbidities, leading to more hospitalizations. ABSTRACT Background Diabetic neuropathy (DN) is the most common chronic complication of Type 2 diabetes mellitus (T2DM), with ...
Jeong SJ, Kim SK, Kim CH.
europepmc +2 more sources
Spectrophotometric determination of thioctic (α-lipoic) acid in water and pharmaceutical preparations [PDF]
A spectrophotometric method is described for the assay of thioctic acid. The method is based on the reaction between the drug and palladium(II) chloride.
Korićanac Zagorka +3 more
doaj +1 more source
Thioctic Acid: Physics, Chemistry, and Biology [PDF]
This paper constitutes a review of the experimental events that led our laboratory to focus its attention on thioctic acid, a discussion of some of the purely chemical and physical properties of thioctic acid that this awakened interest prompted us to ...
Calvin, Melvin
core +1 more source
A Multicenter Trial of an Enhanced Serum Comprised of 13 Plant-Based Adaptogens Targeting Skin Quality in Females Impacted by Hormonal Decline. [PDF]
ABSTRACT Objectives To assess the effectiveness and tolerability of a serum comprised of plant‐based adaptogens (MYS‐REV) for visible improvements in skin changes caused by hormonal fluctuations associated with perimenopause and postmenopause in women. Study Designs A 16‐week open‐label multicenter study evaluated the efficacy and tolerability of twice‐
Draelos ZD, Moradi A, Smathers A.
europepmc +2 more sources

