Therapeutics and Clinical Risk Management, 2011 Courtney E McIlduff, Seward B RutkoveDepartment of Neurology, Beth Israel Deaconess Medical Center, Boston, MA, USABackground: The most common of the neuropathies associated with diabetes mellitus, diabetic sensorimotor polyneuropathy (DSPN) is a ...
McIlduff CE, Rutkove SB
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Use of thioctic acid in complex treatment of acute alcoholic pancreatitis [PDF]
Acta Biomedica Scientifica, 2012 The results of treatment of 27 patients with confirmed. acute alcoholic pancreatitis are studied. It is shown that application of thioctic acid in a dose of 600 mg in a day allows to localize process and to turn it on an aseptic way.
M. S. Funygin, D. B. Demin
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Neuroprotective activity of thioctic acid in central nervous system lesions consequent to peripheral nerve injury. [PDF]
Biomed Res Int, 2013 Peripheral neuropathies are heterogeneous disorders presenting often with hyperalgesia and allodynia. This study has assessed if chronic constriction injury (CCI) of sciatic nerve is accompanied by increased oxidative stress and central nervous system ...
Tomassoni D +6 more
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Modern Approaches to the Technology of Tablet Dosage Forms of Thioctic Acid (Review)
Разработка и регистрация лекарственных средств, 2021 Introduction. Thioctic (α-lipoic) acid is an endogenous antioxidant and is used for liver diseases, poisoning with salts of heavy metals, hyperlipidemia, atherosclerotic heart disease, neuropathy, insulin-resistant forms of diabetes mellitus, etc ...
S. N. Egorova +4 more
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Self-Assembly of Organic-Inorganic Copolymers Toward Bio-Inspired Cementitious Composites. [PDF]
Adv Sci (Weinh)Organic–inorganic copolymerization of calcium silicate hydrate and thioctic acid produces a self‐organized nanocomposite inspired by the disordered collagen–mineral architecture of trabecular bone. The resulting material combines a compressive strength above 300 MPa with intrinsic physical reprocessibility, retaining over 80% of its strength and energy
Xie Z +8 more
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Unveiling the Demographics and Clinical Characteristics of Diabetic Neuropathy: Findings From the National Health Insurance Service, 2012-2017. [PDF]
J DiabetesDiabetic neuropathy prevalence declined from 23.4% to 21.5% between 2012 and 2017. About half received treatment, mainly α‐lipoic acid monotherapy; patients were older with comorbidities, leading to more hospitalizations. ABSTRACT Background Diabetic neuropathy (DN) is the most common chronic complication of Type 2 diabetes mellitus (T2DM), with ...
Jeong SJ, Kim SK, Kim CH.
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EFFECT OF THIOCTIC ACID ENANTIOMETERS ON CARDIAC AND RENAL HYPERTENSIVE DAMAGE. [PDF]
, 2012 Arterial hypertension is accompanied by significant cardiovascular and renal changes as well as by increased production of reactive oxygen species (ROS) Spontaneously hypertensive rats (SHR) are a widely used animal model in hypertension research. They
AMENTA, Francesco +5 more
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Spectrophotometric determination of thioctic (α-lipoic) acid in water and pharmaceutical preparations [PDF]
Journal of the Serbian Chemical Society, 2007 A spectrophotometric method is described for the assay of thioctic acid. The method is based on the reaction between the drug and palladium(II) chloride.
Korićanac Zagorka +3 more
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Thioctic Acid: Physics, Chemistry, and Biology [PDF]
, 1956 This paper constitutes a review of the experimental events that led our laboratory to focus its attention on thioctic acid, a discussion of some of the purely chemical and physical properties of thioctic acid that this awakened interest prompted us to ...
Calvin, Melvin
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Regenerative antibacterial hydrogels from medicinal molecule for diabetic wound repair
Bioactive Materials, 2023 Hydrogel products for chronic diabetic wounds, a serious and prevalent complication of diabetes, show limited effects on disability and remain nonspecific.
Chunxiao Chai +8 more
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