Results 151 to 160 of about 697 (188)
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IR absorption spectrum of thiohydantoin
Soviet Physics Journal, 1970The IR absorption spectrum of thiohydantoin is found in the range 400–3500 cam−1, and the normal-mode frequencies are calculated on the basis of a model. The IR spectrum is interpreted on the basis of the theoretical results, the experimental x-ray spectrum, and the microwave dielectric constants.
R. S. Lebedev +3 more
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Adhesive bonding of noble metals with a thiohydantoin primer
Dental Materials, 2021The purpose of this study was to assess the effects of an experimental primer containing acetone solution and a sulfur-containing functional monomer, 10-methacryloyloxydecyl-(2-thiohydantoin-4-yl)propionate (MDTHP), on the bonds between noble metals and acrylic resin.The experimental primer used as the control for comparison consisted of 6-(4 ...
Akihisa Kodaira +5 more
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Thiohydantoin Nucleosides. Synthesis Approaches
ChemInform, 2004AbstractFor Abstract see ChemInform Abstract in Full Text.
Ahmed I. A. Khodair +2 more
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Derivatives of 2-thiohydantoin as spectrophotometric analytical reagents
Talanta, 1978The synthesis, characteristics, properties and reaction with metallic ions of four pyridine derivatives of 2-thiohydantoin have been studied. 5-(2-Pyridyl)methylene-2-thiohydantoin, 5-(6-methyl-2-pyridyl) methylene-2-thiohydantoin, 5-(di-2-pyridyl)methylene-2-thiohydantoin and 5-[1-(2-pyridyl)-1-methyl] methylene-2-thiohydantoin have been synthesized ...
M T, González +3 more
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Multiple solid-phase synthesis of hydantoins and thiohydantoins
Molecular Diversity, 1997A novel general protocol for the construction of hydantoins and thiohydantoins on a solid support has been developed. Using this novel methodology, the synthesis of a diverse 96-compound library has been achieved. Resin-bound dipeptides are cyclised via the formation of an intermediate isocyanate or isothiocyanate on resin as the key step in the ...
G, Bhalay +4 more
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Thiohydantoins. I. The Preparation of Some 2-Thiohydantoins from Amino Acids and Acylamino Acids
Australian Journal of Scientific Research Series A: Physical Sciences, 1952A reinvestigation of the stepwise degradation of peptides and proteins by the Schlack and Kumpf (1926) procedure, which involves conversion of the terminal carboxyl residue to a 5-substituted-2-thiohydantoin; has been undertaken. The following amino acids or their aoetyl derivatives have been converted by warming with acetic anhydride and ammonium ...
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A New And Convenient Synthesis Of Some Substituted Thiohydantoins
Synthetic Communications, 1999Abstract 3-Substituted thiohydantoins (2a-g) were synthesized in satisfactory yields by the reaction of N-substituted thioureas (la-g) with chloroacetylchloride in the presence of triethylamine under reflux in dioxane. S-Alkylated products (7, 8) were obtained from the reaction of 3-p-tolyl -thiohydantoin (2d) with p-nitrobenzylchloride and 3-phenyl-5 ...
Nohut, F, Durust, Y
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Journal of Medicinal Chemistry, 1986
A series of 5,5-diaryl-2-thiohydantoins and 5,5-diaryl-N3-substituted-2-thiohydantoins related to 5,5-diphenyl-2-thiohydantoin (DPTH) were investigated as potential hypolipidemic agents with the goal of increased potency over DPTH itself. In the 5,5-diaryl class, the best results were obtained by substituting two pyridyl rings for the phenyl rings ...
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A series of 5,5-diaryl-2-thiohydantoins and 5,5-diaryl-N3-substituted-2-thiohydantoins related to 5,5-diphenyl-2-thiohydantoin (DPTH) were investigated as potential hypolipidemic agents with the goal of increased potency over DPTH itself. In the 5,5-diaryl class, the best results were obtained by substituting two pyridyl rings for the phenyl rings ...
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Recent applications of hydantoin and thiohydantoin in medicinal chemistry
European Journal of Medicinal Chemistry, 2019Hydantoin, imidazolidine-2,4-dione, is a non-aromatic five-membered heterocycle, which is considered a valuable, privileged scaffold in medicinal chemistry. The importance of the hydantoin scaffold in drug discovery has been reinforced by several medicines in clinical use, such as phenytoin, nitrofurantoin, and enzalutamide.
SeoHyun Cho, Seok-Ho Kim, Dongyun Shin
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Australian Journal of Scientific Research Series A: Physical Sciences, 1952
Linear anhydrides are formed by the action of acetic anhydride on p-toluene-sulphonylglycine and carbobenzyloxy-glycine, -phenylalanine, and -β-alanine. The anhydrides from the first two acids yield the corresponding 2-thiohydantoin with ammonium thiocyanate in acetic acid. Other methods for the preparation of l-p-toluenesulphonylglycine anhydride, and
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Linear anhydrides are formed by the action of acetic anhydride on p-toluene-sulphonylglycine and carbobenzyloxy-glycine, -phenylalanine, and -β-alanine. The anhydrides from the first two acids yield the corresponding 2-thiohydantoin with ammonium thiocyanate in acetic acid. Other methods for the preparation of l-p-toluenesulphonylglycine anhydride, and
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