Results 41 to 50 of about 427,077 (192)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Evaluation of oxidative stress in gout disease; thiol-disulfide homeostasis and ischemia-modified albumin levels

International Journal of Medical Biochemistry, 2022
INTRODUCTION: Gout is a common and easily treated disease characterized by the accumulation of monosodium urate crystals in both joints and other tissues.
Ahmet Rıfat Balık, Ahmet Omma, Sevinç Can Sandıkçı, Çiğdem Yücel, Murat Kızılgün, Zeynep Büşra Balık, Esra Fırat Oğuz, Salim Neselioglu, Özcan Erel   +8 more
doaj   +1 more source

Optical Detection of Cellular Signals at Material Interfaces

Advanced Healthcare Materials, EarlyView.
Emerging functional materials are transforming optical detection of cellular signals. This review highlights optical techniques that exploit the unique optical properties of diverse materials to detect and quantify cellular electrical, chemical, and mechanical signals, and discusses key opportunities and challenges.
Xuchen Ren, Jitong Ren, Zixin Zhang, Koney Eungkon Kim, Francis L. Hong, Yuecheng Peter Zhou   +5 more
wiley   +1 more source

Thiol-disulfide oxidoreductases: assays, inhibitors, and metabolic roles

, 2022
Thorpe, ColinDisulfide bonds are common post-translational modifications which serve to stabilize or impart function onto proteins. Although this product of oxidation between two cysteine thiols is relatively stable, disulfide bonds are able to undergo ...
Foster, Celia K.
core   +1 more source

Chemical Strategies for Multistimuli Responsive Dynamic Covalent Materials in Regenerative Medicine

Advanced Healthcare Materials, EarlyView.
Multistimuli responsive dynamic covalent materials integrate reversible chemistry with the complex chemical, mechanical, and biochemical cues of regenerative environments. This review highlights chemical strategies based on orthogonal dynamic bonds, multicomponent networks, and hierarchical architectures to regulate mechanics, degradation, and ...
Saurabh Joshi, Matthew B. Baker, Dominik Schauenburg   +2 more
wiley   +1 more source

Thiol/disulfide homeostasis in patients with ankylosing spondylitis [PDF]

, 2016
Ankylosing spondylitis (AS) is a chronic inflammatory disease. In many inflammatory diseases, increased production of pro-inflammatory cytokines is associated with an increase in oxidative stress mediators.
Dogru, Atalay, Ayse Balkarli, Sahin, Mehmet, Balkarli, Ayse, Gozde Yildirim Cetin, Neselioglu, Salim, Erel, Ozcan, Mehmet Sahin, Sevket Ercan Tunc, Atalay Dogru, Tunc, Sevket Ercan, Cetin, Gozde Yildirim, Salim Neselioglu, Ozcan Erel   +13 more
core   +1 more source

Thiol-Disulfide Homeostasis in Noise-Induced Hearing Loss in Rats. [PDF]

J Int Adv Otol
BACKGROUND: This study was designed to assess if thiol-disulfide homeostasis could be used as diagnostic biomarker in noise-induced hearing loss (NIHL) in a laboratory animal model. METHODS: The study was carried out with a total of 28 female albino rats
Aydın E, Mungan Durankaya S, Yilmaz O, Kirkim G, Aktaş S, Neşelioğlu S, Erel Ö, Olgun Y, Dalgıç A.   +8 more
europepmc   +2 more sources

Engineering Microbial Particles for Next‐Generation Biomedical Platforms

Advanced Science, EarlyView.
Microbe‐derived particles (MDPs), which include extracellular vesicles, outer membrane vesicles, inclusion bodies, polysaccharide particles, and virus‐like particles, represent a rapidly expanding category of bioinspired nanomaterials. With their natural origin, intrinsic biocompatibility, and highly programmable functionality, MDPs serve as a ...
Yuting Li, Yunjie Lu, Ziyan Huang, Jianjiang Chen, Yanbin Liu, Lei Qin, Chao Wang, Yumin Wu   +7 more
wiley   +1 more source

Thiol/disulphide homeostasis in men with heroin addiction [PDF]

Düşünen Adam Psikiyatri ve Nörolojik Bilimler Dergisi, 2014
Objective: Heroin addicts have increased oxidative stress which can disturb thiol/disulfide (SH/SS) homeostasis, causing disulfide formation. No study has determined the serum thiol amount and blood disulfide amount in heroin addicts.
vahap ozan kotan, fatma meric yilmaz, salim neselioglu, ozcan erel, ihsan tuncer okay, serkan kiral, abdurrahim bakirhan, erol goka   +7 more
doaj  

The Evaluation of Thiol/Disulfide Homeostasis in Diabetic Nephropathy

Endocrinology Research and Practice, 2018
Thiol/disulfide homeostasis plays a critical role in antioxidant defense, detoxification, apoptosis, enzyme activities, transcription and cellular signal transduction.
Mehmet Ali Eren, İsmail Koyuncu, Hatice İncebıyık, Hilal Karakaş, Özcan Erel, Tevfik Sabuncu   +5 more
doaj   +1 more source