Results 1 to 10 of about 210,017 (120)
Pharmaceutics, 2021 A family of monomodified bovine serum albumin (BSA) linked to methotrexate (MTX) through a variety of spacers was prepared. All analogues were found to be prodrugs having low MTX-inhibitory potencies toward dihydrofolate reductase in a cell-free system ...
Itzik Cooper +3 more
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Thiol/disulfide homeostasis in gastritis with or without Helicobacter pylori
International Journal of Medical Biochemistry, 2022 INTRODUCTION: In this study, it was aimed to evaluate how thiol/disulfide homeostasis is affected in Helicobacter pylori positive and negative gastritis and the efficiency of thiol/disulfide levels in the diagnosis of chronic gastritis. METHODS: Seventy
Yakup Dulgeroglu, Osman Bandirmali
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Ischemia modified albumin level and thiol/disulfide homeostasis in the etiology of tinnitus
International Journal of Medical Biochemistry, 2022 INTRODUCTION: Although many theories about the etiology of tinnitus have been proposed, it has not been fully clarified. In this study, we investigated the role of ischemia in the etiology of tinnitus.
Hüseyin Kurku +4 more
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Pharmaceutics, 2023 In this study, diselenide (Se–Se) and disulfide (S–S) redox-responsive core-cross-linked (CCL) micelles were synthesized using poly(ethylene oxide)2k-b-poly(furfuryl methacrylate)1.5k (PEO2k-b-PFMA1.5k), and their redox sensitivity was compared. A single
Sonyabapu Yadav +8 more
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α-Conotoxin Peptidomimetics: Probing the Minimal Binding Motif for Effective Analgesia
Toxins, 2020 Several analgesic α-conotoxins have been isolated from marine cone snails. Structural modification of native peptides has provided potent and selective analogues for two of its known biological targets—nicotinic acetylcholine and γ-aminobutyric acid ...
Adam C. Kennedy +5 more
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A native chemical chaperone in the human eye lens
eLife, 2022 Cataract is one of the most prevalent protein aggregation disorders and still the most common cause of vision loss worldwide. The metabolically quiescent core region of the human lens lacks cellular or protein turnover; it has therefore evolved ...
Eugene Serebryany +7 more
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Frontiers in Molecular Biosciences, 2023 Thioredoxin/glutathione reductase (TGR) from the platyhelminthic parasitic worms has recently been identified as a drug target for the treatment of schistosomiasis.
Madison M. Smith, Graham R. Moran
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Dynamic thiol/disulfide homeostasis in serum of patients with generalized vitiligo [PDF]
Archives of Biological Sciences, 2019 Vitiligo is a multifactorial disorder commonly associated with hypo-/depigmentation in the skin and may influence both children and adults psychologically because of the notable leopard-skin-like appearance.
Pektaş Gökhan +6 more
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Ideal timing of labor in terms of oxidative stress – which term period is best?
Türk Biyokimya Dergisi, 2023 To determine the ideal timing of labor for term pregnancies using oxidative stress determiners.
Yilmaz Gamze +8 more
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Frontiers in Chemistry, 2020 Heterogenization of homogenous catalysts on electrode surfaces provides a valuable approach for characterization of catalytic processes in operando conditions using surface selective spectroelectrochemistry methods.
Mauricio Cattaneo +10 more
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