Results 41 to 50 of about 4,427 (167)

Relationship between hTERT levels and oxidative stress in epilepsy patients. [PDF]

Epilepsia Open
Abstract Objective Human telomerase reverse transcriptase (hTERT) is a key determinant of telomere maintenance and cellular aging. Oxidative stress plays a role in neurodegenerative processes by causing cellular damage through increased reactive oxygen species.
Üremiş MM, Tuncel Berktaş D, Üremiş N, İnanç Tolun F.   +3 more
europepmc   +2 more sources

Evaluation of Thiol Disulphide Homeostasis and Neutrophile Lymphocyte Ratio in Carbon Monoxide Intoxication

Ankara Medical Journal, 2020
INTRODUCTION: The aim of this study is to search if using thiol/disulphide homeostasis together with Neutrophile Lymphocyte Ratio (NLR) which are oxidative stress markers in patients who apply to the emergency service with carbon monoxide intoxication is
Fatih Tanrıverdi, Yucel Yuzbasioglu, Fadime Güllü Ercan Haydar, Servan Gökhan, Ayhan Özhasenekler, Çağdaş Yıldırım, Fatih Ahmet Kahraman, Funda Eren   +7 more
doaj   +1 more source

Investigating the Impact of the ECT on Thiol-Disulphide Homeostasis in Depressive Disorders

Psychiatry and Clinical Psychopharmacology, 2021
Bacground: Depressive disorders are characterized by oxidative stress and burden of oxidative stress may provoke cellular and biochemical challenges. Thiols are converted into non-reactive disulphides after reacting with oxygen radicals and converted ...
Murat Ilhan Atagun, Mehmet Cem Ilnem, Nesrin Karamustafalioglu, Almila Senat, Suat Yalcin, Baris Alpugan, Derya Ipekcioglu, Ozlem Balaban, Ozge Canbek Atay, Ozcan Erel   +9 more
doaj   +1 more source

Assessment of Thiol/Disulphide Homeostasis in Patients with Knee Osteoarthritis

, 2021
Our aim was to explore the thiol/disulphide homeostasis and the link with functional status in patients who have knee OA. Sixty knee OA patients and 50 healthy individuals were enrolled in this study. We measured serum levels of native thiol, total thiol
Beyazal, Munevver Serdaroglu, Devrimsel, Gul, Arpa, Medeni, Erel, Ozcan   +3 more
core   +1 more source

Dynamic thiol/disulphide homeostasis metrics as a risk factor for peripheral arterial disease

, 2021
Objective To examine dynamic thiol/disulphide homeostasis metrics as a novel risk factor of oxidative stress in patients with peripheral arterial disease.
BAL, CEYLAN, Erdem, Kemalettin, Cayir, Mustafa Cagdas, Yuksel, Ahmet, BORULU, Ferhat, Devay, Seda Duygulu, ÇETİNKAYA, AYHAN, Ucaroglu, Erhan Renan, Kumtepe, Gencehan, Gok, Gamze, Korkmaz, Ufuk Turan Kursat, VELİOĞLU, YUSUF   +11 more
core   +2 more sources

Protein-Driven Copper Redox Regulation: Uncovering the Role of Disulphide Bonds and Allosteric Modulation. [PDF]

Angew Chem Int Ed Engl
Copper binding triggers structural changes that expose a reactive disulphide bridge, enabling intrinsic Cu(II) reduction in folded proteins. SAXS, XAS, and QM/MM simulations reveal how globular proteins such as HSA and SOD1 employ disulphide‐mediated dynamics to modulate site accessibility and control copper redox chemistry.
Sternke-Hoffmann R, Liu C, Wang X, Pupart H, Sun X, Dreiser JG, Palumaa P, Liao Q, Krack M, Luo J.   +9 more
europepmc   +2 more sources

Increased oxidative stress is associated with thiol/disulphide homeostasis in clomiphene citrate resistant polycystic ovary syndrome

, 2021
The purpose of this study was to evaluate the relation CC resistant PCOS and the thiol/disulphide homeostasis, used as a marker of OS, by measuring that exchange using a novel technique.
Ege, Serhat, Ozgun, Zinet, Bademkiran, Muhammet Hanifi, Bagli, Ihsan, Erdem, Selami, Peker, Nurullah, Erel, Ozcan   +6 more
core   +2 more sources

Serum thiol disulphide levels among sheep with sarcoptic mange [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2019
Sarcoptic mange, a notable parasitic disease, causes dermatological alterations among ruminants. Thiol-disulphite hemostasis is a novel oxidative stress parameter.
İlker ÇAMKERTEN, Güzin ÇAMKERTEN, Hasan ERDOĞAN, Adnan AYAN, Songül ERDOĞAN, Kerem URAL   +5 more
doaj   +1 more source

Thiol – Disulphide Homeostasis in Polycythemia Vera

Dicle Tıp Dergisi, 2019
Background: Thiol-disulphide homeostasis has vital role in cell signalling mechanisms, regulation of transcription factors and enzymatic activities, signal transduction and regulation of proliferation rate, apoptosis and detoxification and antioxidant protective mechanism.
ŞENTÜRK YIKILMAZ, Aysun, BAKANAY, Şule Mine, AKİNCİ, Sema, MARAL, Senem, MUSTAFAYEV, Fuad, ALİSİK, Murat, EREL, Özcan, DİLEK, İmdat   +7 more
openaire   +4 more sources

An Evaluation of Oxidative Stress With Thiol/Disulfide Homeostasis in Patients With Persistent Allergic Rhinitis

Ear, Nose & Throat Journal, 2022
Background: We evaluated the efficacy of medical treatment on thiol–disulfide balance despite ongoing allergic stimulation. Methods: The research design was a prospective observational study that included 35 persistent allergic rhinitis (AR) patients ...
Ayse E. Göker MD, Maide H. Alagöz MD, Tolgar L. Kumral MD, Semih Karaketir MD, Ayça B. Yilmazer MD, Belgin Tutar MD, Esmail A. Ahmed MD, Cemile Biçer MD, Yavuz Uyar MD   +8 more
doaj   +1 more source