Results 61 to 70 of about 361,307 (140)

Methamphetamine’s effects on oxidative stress markers may continue after detoxification: a case–control study

Psychiatry and Clinical Psychopharmacology, 2019
OBJECTIVE: Substance use disorder (SUD) is a critical public health problem. The use of methamphetamine is increasing daily worldwide. The aetiology of SUD is related to numerous factors that have not been fully elucidated.
Yunus Hacimusalar, Ozgul Karaaslan, Ceylan Bal, Derya Kocer, Gamze Gok, Bayram Yildiz   +5 more
doaj   +1 more source

Altered Maternal Serum Dynamic Thiol-Disulfide Interchange Reactions in Pregnant Women with Gestational Diabetes Mellitus

Gynecology Obstetrics & Reproductive Medicine, 2016
OBJECTIVE: We aimed to evaluate the alteration of dynamic thiol/disulfide homeostasis which basically shows the oxidative stress in body in pregnant women with gestational diabetes mellitus (GDM) by using a newly developed and automated analysis method.
Melahat Yıldırım, Esengül Türkyılmaz, Büşra Demir Cendek, Gülcan Dauletkazin, Murat Alışık, Pervin Baran, Ayşegül Cinkaya, Ayşe Filiz Avşar Yavuz   +7 more
doaj   +1 more source

Genomic Correlates of Disease Recovery in Natural Populations of the Sierra Nevada Yellow‐Legged Frog (Rana sierrae)

Molecular Ecology, Volume 35, Issue 8, April 2026.
ABSTRACT In our rapidly changing world, evolution is likely to play an important role in facilitating the resilience of wildlife populations. The Sierra Nevada yellow‐legged frog (Rana sierrae) provides a rare example of recovery following severe declines caused by the amphibian chytrid fungus (Batrachochytrium dendrobatidis).
Allison Q. Byrne, Andrew P. Rothstein, Roland A. Knapp, Erica Bree Rosenblum   +3 more
wiley   +1 more source

Thiol redox homeostasis in neurodegenerative disease

Redox Biology, 2015
This review provides an overview of the biochemistry of thiol redox couples and the significance of thiol redox homeostasis in neurodegenerative disease.
Gethin J. McBean, Mutay Aslan, Helen R. Griffiths, Rita C. Torrão   +3 more
doaj   +1 more source

NOTCH3 CADASIL Variant Receptor Aggregation Requires NOTCH3 Wild‐Type Receptors: Identification of Highly Selective Inhibitors That Block the Process

The FASEB Journal, Volume 40, Issue 6, 31 March 2026.
CADASIL is the major cause of early‐onset stroke and cognitive dysfunction, including dementia. It is caused by mutations in the NOTCH3 receptor that result in the formation of protein aggregates in the small vessel walls of the brain. We demonstrated that NOTCH3 CADASIL variant receptor aggregation is strictly dependent on interactions with NOTCH3 ...
Haijiang Wang, Xinxin Liu, Gido Gravesteijn, Alessia Atella, Jin Liu, Julie W. Rutten, Peter ten Dijke, Manuel A. F. V. Gonçalves, Saskia A. J. Lesnik Oberstein, David A. Baker   +9 more
wiley   +1 more source

The association of dynamic thiol-disulfide homeostasis and inflammatory markers in patients with polycystic ovary syndrome

Taiwanese Journal of Obstetrics & Gynecology, 2020
Objective: Polycystic ovary syndrome (PCOS) is a common hormonal disorder among women of reproductive age characterized by irregular menstruation and hirsutism and is associated with an increased risk for cardiovascular diseases.
Gültekin Adanaş Aydın, Hilal Gülsüm Turan Özsoy, Handan Ankaralı, Gülten Özgen, Salim Neşelioğlu   +4 more
doaj   +1 more source

GhSTH‐2 Integrates Host Redox Signalling and Effector Recognition and Confers Resistance Against Verticillium dahliae in Cotton

Molecular Plant Pathology, Volume 27, Issue 3, March 2026.
The fungal effector VdEPG1, secreted by Verticillium dahliae, interacts with the PR10/Bet v1‐like protein GhSTH‐2. This interaction activates GhSTH‐2‐mediated enhancement of cotton disease resistance through GhTXNDC9‐dependent ROS signalling, while simultaneously enabling VdEPG1 to suppress GhSTH‐2‐induced immunogenic necroptosis.
Siyu Zhang, Jinglong Zhou, Zili Feng, Feng Wei, Lihong Zhao, Yalin Zhang, Heqin Zhu, Hongjie Feng   +7 more
wiley   +1 more source

Chelation Therapy for Rare Earth Element Toxicity: Current Evidence, Challenges and Future Directions

Basic &Clinical Pharmacology &Toxicology, Volume 138, Issue 1, January 2026.
ABSTRACT The accelerating integration of rare earth elements (REEs) in advanced technologies has generated rising concern over human exposure and the attendant toxicological risks. This review presents an up‐to‐date synthesis of current evidence on REE toxicity across multiple exposure pathways, including inhalation, ingestion and occupational contact,
Jose L. Domingo
wiley   +1 more source

Cadmium and Cadmium Nano‐Based Materials: Exploration of Their Toxicity and Carcinogenic and Anticarcinogenic Properties

Journal of Nanotechnology, Volume 2026, Issue 1, 2026.
Introduction Exposure to cadmium (Cd) can result in cancer and toxicity to various organ systems, including the reproductive system, peripheral nervous system and respiratory system, among others. Cadmium (Cd) is classified as a Group 1 carcinogen by the International Agency for Research on Cancer (IARC) due to its ability to induce oxidative stress ...
Relebohile Lefojane, Ayodeji Adegoke, Mamello Sekhoacha, Dhruba Jyoti Majumdar   +3 more
wiley   +1 more source

Dynamic thiol/disulphide homeostasis in patients with newly diagnosed primary hypertension

, 2016
We aimed to investigate the thiol/disulphide homeostasis in patients with newly diagnosed primary hypertension with a novel and automated method. Blood thiol/disulphide homeostasis, which consists of native thiol/disulphide exchanges, was investigated in
EREL, ÖZCAN, Yilmaz, FATMA MERİÇ, Dede, Fatih, Ozkayar, Nihal, Yilmaz, Nisbet, Ivan, Bayram, Topcuoglu, Canan, NEŞELİOĞLU, SALİM, Ates, Ihsan   +8 more
core   +1 more source