Results 61 to 70 of about 4,427 (167)

Evolutionary Conserved and Divergent Responses to Copper Zinc Superoxide Dismutase Inhibition in Plants

open access: yesPlant, Cell &Environment, EarlyView.
ABSTRACT After an initial evolution in a reducing environment, life got successively challenged by reactive oxygen species (ROS), especially during the great oxidation event (GOE) that followed the development of photosynthesis. Therefore, ROS are deeply intertwined into the physiological, morphological and transcriptional responses of most present‐day
Stephanie Frohn   +12 more
wiley   +1 more source

Dynamic Thiol/Disulphide Homeostasis in Patients with Vaginitis [PDF]

open access: yesJournal of Gynecology and Obstetrics, 2018
This study investigated the thiol-disulphide balance in vaginitis, which is a local inflammatory condition, through the use of a new method. A cross-sectional study involving 82 women (45 women with vaginitis and 37 women in control group) was conducted at Ataturk Education and Research Hospital, Ankara, Turkey from February 2016 to April 2016.
YILDIRIM, MELAHAT   +5 more
openaire   +3 more sources

Racemisation of Amino Acids: From Synthetic Challenge to Biological Significance

open access: yesChemBioChem, Volume 27, Issue 11, 15 June 2026.
Racemisation, once considered an undesirable synthetic side reaction, also occurs naturally in amino acids and influences biological processes. Evidence links stereochemical conversion to ageing, protein turnover, and cellular development. This review examines mechanisms, control strategies in synthesis, applications and implications in physiology ...
Othman Al Musaimi
wiley   +1 more source

Evaluation of oxidative stress assocıated with altered Thiol/Disulphide homeostasis in cats with feline Coronavirus infection

open access: yesRevista Científica
This study evaluated thiol/disulphide homeostasis and its relationship with oxidative stress in cats diagnosed with feline coronavirus infection.
Melek Aydemir Hökelekli   +5 more
doaj   +1 more source

Genomic Correlates of Disease Recovery in Natural Populations of the Sierra Nevada Yellow‐Legged Frog (Rana sierrae)

open access: yesMolecular Ecology, Volume 35, Issue 8, April 2026.
ABSTRACT In our rapidly changing world, evolution is likely to play an important role in facilitating the resilience of wildlife populations. The Sierra Nevada yellow‐legged frog (Rana sierrae) provides a rare example of recovery following severe declines caused by the amphibian chytrid fungus (Batrachochytrium dendrobatidis).
Allison Q. Byrne   +3 more
wiley   +1 more source

Periodontal Health and Salivary Thiol-Disulphide Homeostasis in Multiple Sclerosis Patients

open access: yesSüleyman Demirel Üniversitesi Tıp Fakültesi Dergisi
Objective: Multiple sclerosis (MS) is a chronic autoimmune disease in which neuroinflammation and oxidative stress play important roles in its pathology.
Fatma Yeşim Kırzıoğlu   +5 more
doaj   +1 more source

NOTCH3 CADASIL Variant Receptor Aggregation Requires NOTCH3 Wild‐Type Receptors: Identification of Highly Selective Inhibitors That Block the Process

open access: yesThe FASEB Journal, Volume 40, Issue 6, 31 March 2026.
CADASIL is the major cause of early‐onset stroke and cognitive dysfunction, including dementia. It is caused by mutations in the NOTCH3 receptor that result in the formation of protein aggregates in the small vessel walls of the brain. We demonstrated that NOTCH3 CADASIL variant receptor aggregation is strictly dependent on interactions with NOTCH3 ...
Haijiang Wang   +9 more
wiley   +1 more source

GhSTH‐2 Integrates Host Redox Signalling and Effector Recognition and Confers Resistance Against Verticillium dahliae in Cotton

open access: yesMolecular Plant Pathology, Volume 27, Issue 3, March 2026.
The fungal effector VdEPG1, secreted by Verticillium dahliae, interacts with the PR10/Bet v1‐like protein GhSTH‐2. This interaction activates GhSTH‐2‐mediated enhancement of cotton disease resistance through GhTXNDC9‐dependent ROS signalling, while simultaneously enabling VdEPG1 to suppress GhSTH‐2‐induced immunogenic necroptosis.
Siyu Zhang   +7 more
wiley   +1 more source

Chelation Therapy for Rare Earth Element Toxicity: Current Evidence, Challenges and Future Directions

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 138, Issue 1, January 2026.
ABSTRACT The accelerating integration of rare earth elements (REEs) in advanced technologies has generated rising concern over human exposure and the attendant toxicological risks. This review presents an up‐to‐date synthesis of current evidence on REE toxicity across multiple exposure pathways, including inhalation, ingestion and occupational contact,
Jose L. Domingo
wiley   +1 more source

Cadmium and Cadmium Nano‐Based Materials: Exploration of Their Toxicity and Carcinogenic and Anticarcinogenic Properties

open access: yesJournal of Nanotechnology, Volume 2026, Issue 1, 2026.
Introduction Exposure to cadmium (Cd) can result in cancer and toxicity to various organ systems, including the reproductive system, peripheral nervous system and respiratory system, among others. Cadmium (Cd) is classified as a Group 1 carcinogen by the International Agency for Research on Cancer (IARC) due to its ability to induce oxidative stress ...
Relebohile Lefojane   +3 more
wiley   +1 more source

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