Results 221 to 230 of about 141,892 (269)

Mercaptobenzothiazole allergenicity—role of the thiol group

Cutaneous and Ocular Toxicology, 2008
The rubber accelerator, 2-mercaptobenzothiazole (MBT), is known to cause allergic contact dermatitis (ACD), but the mechanism is unknown. The role of the thiol group in MBT's allergenicity was investigated in the present study. Guinea pigs were sensitized to MBT using a modified guinea pig maximization test (GPMT) and reactivity was assessed toward 2 ...
Itai, Chipinda, Xing-Dong, Zhang, Reuben H, Simoyi, Paul D, Siegel   +3 more
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The thiol groups of jack bean urease

Archives of Biochemistry and Biophysics, 1970
Abstract In aqueous buffer solutions both NEM and DTNB rapidly react with 26–28 SH groups per native urease molecule with no loss of enzymatic activity. Titration of a further 7–9 SH groups by either reagent is less rapid and is accompanied by inactivation.
A T, Andrews, F J, Reithel
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Thiols and the diazo group in photoaffinity labels

Biochemical and Biophysical Research Communications, 1980
The photoactivable carbene precursor, 2-diazo-3,3,3-tri-fluoro-propionyloxy group, has been introduced recently for light-induced covalent crosslinking in studies of protein-phospholipid interactions in biomem-branes. The diazo group in this reagent has now been shown to undergo reduction in the dark by a number of thiols (dithiothreitol, 2 ...
Y, Takagaki, C M, Gupta, H G, Khorana
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Essential Role of Thiol Groups in Carboxylase

Nature, 1952
ESSENTIAL thiol groups of enzymes are usually detected by the inactivation of the enzyme with sulphydryl reagents, such as substances forming mercaptide, or oxidizing or alkylating substances1. Yeast carboxylase seems to be affected in a rather uneven and contradictory way by sulphydryl group detectors since 4-aminophenyldichloroarsine2, p ...
A O M, STOPPANI, A S, ACTIS, J O, DEFERRARI, E L, GONZALEZ   +3 more
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Phthalimidomethyl Group. A New Protecting Group of Thiols

Chemistry Letters, 1994
Abstract Phthalimidomethyl group is employed as a protecting group of thiols. This group can be introduced to thiols under mild reaction conditions and be removed by treatment with hydrazine hydrate followed by mercuric acetate or cupric acetate.
Young-Dae Gong, Nobuharu Iwasawa
openaire   +1 more source

Reflections on the Role of the Thiol Group in Biology

Annals of the New York Academy of Sciences, 2000
Abstract: This essay is concerned with the role of the thiol or sulfhydrvl group in cellular function and metabolism and with the important investigations over many years that have led us to a better understanding of the importance of this molecular moiety that plays such a vital role in biology. The tools for measuring the SH group and for inhibiting
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The role of thiol groups in nucleoside transport

Molecular and Cellular Biochemistry, 1976
(1) The inactivation of various forms of nucleoside transport with reagents blocking thiol groups was studied in whole cells of E. coli B. No positive correlation between the efficiency of active transport and the extent or rate of inactivation could be demonstrated.
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Modification of thiol groups in cytoplasmic aldehyde dehydrogenase

Alcohol, 1985
It is proposed that cytoplasmic aldehyde dehydrogenase possesses a pair of important reactive thiol groups, A and B. Group A is labelled by disulfiram and the enzyme is inactivated; subsequently group B displaces the dithiocarbamate label and an enzymic disulphide is formed.
T M, Kitson, K M, Loomes
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Are Tyrosinase and Thiol Groups Present in Skin Epithelium?

Nature, 1950
WHEN an aqueous solution of 1:2:4-trihydroxynaphthalene (dihydrolawsone) is applied to the skin, immediate oxidation to the orange-yellow 2-hydroxy-1:4-naphthaquinone (lawsone) (I) occurs, presumably because of the presence in the skin of an oxidase system.
H, BURTON, J M, WILLIAMS
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Activated polyurethane modified with latent thiol groups

Biomaterials, 2002
A novel type of modified polyurethane with pendant acetylthio groups (as a latent form of thiol groups) has been proposed for the use in surface modifications with various biomolecules. The polymer was prepared via a modified variant of low-temperature bromoalkylation of urethane hard segments followed by the reaction of pendant bromoalkyl groups with ...
Ivan S, Alferiev, Ilia, Fishbein
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