Results 241 to 250 of about 9,256,330 (314)

The storage condition and duration differentially affect the internal quality and oxidative stability of eggs from aged laying hens. [PDF]

Poult Sci
Camargo SMP, Oliveira HF, Silva JMSD, Nascimento KM, Cordeiro DA, da Silva FL, Gomes RR, Racanicci AMC, Stringhini JH.   +8 more
europepmc   +1 more source

Targeting LDHA Palmitoylation Sensitizes GBM to Chemoradiotherapy via Suppressing Palmitic Acid Induced Glycolytic Reprogramming

Advanced Science, EarlyView.
Mesenchymal GSCs preferentially uptake palmitic acid, thereby promoting ZDHHC12‐mediated LDHA palmitoylation. This modification enhances LDHA enzymatic activity, drives glycolytic reprogramming, and facilitates exosomal LDHA‐mediated TAM regulation.
Zijie Gao, Rongrong Zhao, Zheyuan Chen, Qingtong Wang, Huanyu Yang, Boyan Li, Yanhua Qi, Shulin Zhao, Jixing Zhao, Jiawei Qiu, Ziwen Pan, Zhe Han, Ruochuan Li, Huize Xia, Weijie Tang, Xing Guo, Ping Zhang, Hongyu Zhao, Xu Qian, Gang Li, Hao Xue   +20 more
wiley   +1 more source

Lipoic Acid Derivative/PEI Composite Nanoparticles Enable Efficient mRNA Delivery via Thiol-Mediated Cellular Uptake. [PDF]

Macromol Biosci
Zhang L, Gao Y, Hu Z, Chen Y, Wu C, Shuai Q, Yan Y.   +6 more
europepmc   +1 more source

WGM Single‐Molecule Validation of pH‐Dependent Molecular Energetics at Gold Nanointerfaces: Influence of Buffer Molecules on Glyphosate Ligand Binding

Advanced Science, EarlyView.
Single‐molecule optical sensing reveals how pH and buffer molecules regulate glyphosate interactions with gold nanorods. Combined experiments and theoretical calculations show that changes in molecular charge and competition from buffer species determine whether glyphosate binds transiently or persistently.
Kulathunga Mudalige Kalani Perera, Srikanth Pedireddy, Sivaraman Subramanian, Frank Vollmer   +3 more
wiley   +1 more source

A Chemical Framework for Engineering Extracellular Vesicles' Biointerface to Advance Precision Therapeutics. [PDF]

Adv Mater
Pourtalebi Jahromi L, Geng F, Frenzke JN, Fuhrmann G.   +3 more
europepmc   +1 more source

Ultrasound‐Activated Nanoinhibitors Blocking the Chemo‐Immune Checkpoint to Overcome Chemotherapy‐Induced Immune Resistance

Advanced Science, EarlyView.
A sono‐responsive chemo‐immune checkpoint nanoinhibitor (Sono‐TT8) co‐delivering TPZ chemotherapy and siXkr8 simultaneously kills tumor cells and blocks PS externalization, reversing chemotherapy‐induced immunosuppression and enhancing antitumor immunity. ABSTRACT Breast cancer features an immunosuppressive tumor microenvironment following chemotherapy
Yunfan Liu, Chier Du, Leilei Zhu, Hongjin An, Shengzhe Hou, Yi Lan, Xuemei Tang, Min Xu, Peng Luo, Hua Teng, Hao Yang, Xun Guo, Jianli Ren, Zhiyi Zhou   +13 more
wiley   +1 more source

Acute Systemic Oxidative Stress Response to Fine-Needle Aspiration Biopsy in Thyroid Nodules. [PDF]

Diagnostics (Basel)
Karahmetli G, Aydın C, İnce N, Akdoğan L, Altay FP, Özdemir D, Eren F, Erel Ö, Topaloğlu O, Ersoy R, Çakır B.   +10 more
europepmc   +1 more source

Rapid‐Forming Conductive Antifouling Hydrogel Coating Enables Magnetically Guided Electrochemical POCT for Direct at‑Home Blood Testing

Advanced Science, EarlyView.
The SPG‐MpECis electrochemical POCT platform developed in this study enables direct detection of biomarkers in complex biological samples such as serum and fingerstick blood, demonstrating high concordance with results from clinical reference methods and holding broad potential for at‐home testing applications.
Menghan Li, Kai Su, Ruiwei Hu, Ke Gao, Yuanjie Liu, Lu Zhang, Ningke Fan, Yirong Chen, Wei Cheng, Shijia Ding, Haiping Wu   +10 more
wiley   +1 more source

Protective effects of Crocin on hepatic steatosis, oxidative stress, and lipid profile in an animal model of non-alcoholic fatty liver disease. [PDF]

PLoS One
Rezayee H, Fahmidehkar MA, Beheshti F, Ghoryani M, Yousefpoor Y, Hossaini D, Ilbeigi D.   +6 more
europepmc   +1 more source

Pathological Signal‐Responsive Nanoplatforms for Sepsis: Integrating Biomarker Sensing With Spatiotemporal Drug Delivery and Immunomodulation

Advanced Science, EarlyView.
Biomarker‐triggered nanoplatforms transform sepsis therapy by coupling pathological sensing with precision drug release. This review reveals how microenvironment‐responsive nanomedicines enable stage‐specific intervention, improve therapeutic efficacy, and minimize systemic toxicity, while highlighting emerging opportunities for AI‐assisted and ...
Yukun Liu, Kang Wang, Kwet Kyawl Yan, Zhikai Xu, Xuan Zhao, Xiangjun Bai, Zhanfei Li, Yuchang Wang   +7 more
wiley   +1 more source