Results 21 to 30 of about 141,892 (269)

Regular exercise, overweight/obesity and sedentary lifestyle cause adaptive changes in thiol–disulfide homeostasis

open access: yesAnais da Academia Brasileira de Ciências, 2019
: Dynamic thiol–disulfide homeostasis is considered to have critical roles in maintenance of physiological functioning. We aimed to reveal whether there is any specific aberration in thiol–disulfide homeostasis in three distinct categories of individuals,
MEHMET GOL   +3 more
doaj   +1 more source

Assessment of correlation of oxidative stress and insulin resistance with glucose-6-phosphate dehydrogenase activity in Type II diabetes mellitus patients

open access: yesJournal of Pharmacy and Bioallied Sciences, 2021
Background: The present study aimed to assess the correlation of oxidative stress glucose-6-phosphate dehydrogenase (G6PD) activity in type II diabetes mellitus (DM) patients.
Beena Singh, Shweta Kumari
doaj   +1 more source

THIOL GROUPS IN DEOXYRIBONUCLEIC ACID NUCLEOTIDYLTRANSFERASE [PDF]

open access: yesBiochemical Journal, 1965
1. The inhibitory effects of iodoacetate, iodoacetamide, p-hydroxymercuribenzoate and sarkomycin were studied in a partially purified preparation of deoxyribonucleic acid nucleotidyltransferase from Landschutz ascites-tumour cells. All of these agents inhibited the activity of the enzyme, and it was shown that the inhibition exerted by the last three ...
H M, KEIR, J B, SHEPHERD
openaire   +2 more sources

Effect of Extraction Method on the Structure and Performance of Keratin Hydrogel

open access: yesPige Kexue Yu Gongcheng
Keratin-based hydrogels have been used more and more in the fields of biomedical materials and cosmetics. However, there are obvious differences in the molecular weight and its distribution as well as the content of active sulfhydryl groups of keratin ...
Xin LI, Die ZOU, Haiming CHENG
doaj   +1 more source

An Investigation of Oxidative Stress and Thiol/Disulphide Homeostasis in Graves’ Disease

open access: yesMedicina, 2019
Background and objectives: The aim of this study was to research oxidative stress and thiol/disulphide homeostasis in Graves’ patients. Materials and Methods: The study included 33 Graves’ patients (research group) and 35 healthy subjects ...
Veysel Agan   +7 more
doaj   +1 more source

Thiol/disulfide homeostasis in gastritis with or without Helicobacter pylori

open access: yesInternational Journal of Medical Biochemistry, 2022
INTRODUCTION: In this study, it was aimed to evaluate how thiol/disulfide homeostasis is affected in Helicobacter pylori positive and negative gastritis and the efficiency of thiol/disulfide levels in the diagnosis of chronic gastritis. METHODS: Seventy
Yakup Dulgeroglu, Osman Bandirmali
doaj   +1 more source

Pathways of peroxynitrite oxidation of thiol groups [PDF]

open access: yesBiochemical Journal, 1997
Peroxynitrite mediates the oxidation of the thiol group of both cysteine and glutathione. This process is associated with oxygen consumption. At acidic pH and a cysteine/peroxynitrite molar ratio of ≤ 1.2, there was a single fast phase of oxygen consumption, which increased with increasing concentrations of both cysteine and oxygen.
C, Quijano   +4 more
openaire   +2 more sources

The Role of Follicular Fluid Thiol/Disulphide Homeostasis in Polycystic Ovary Syndrome

open access: yesBalkan Medical Journal, 2018
Background: Oxidative stress has been proposed as a potential trigger in the etiopathogenesis of polycystic ovary syndrome-related infertility. Thiol/disulphide homeostasis, a recently identified oxidative stress marker, is one of the antioxidant ...
Esra Nur Tola   +5 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

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