Mucoadhesive properties of low molecular weight chitosan- or glycol chitosan- and corresponding thiomer-coated poly (isobutylcyanoacrylate) core-shell nanoparticles [PDF]
, 2017 The aim of the present work was to evaluate the mucoadhesive properties of poly(isobutyl cyanoacrylate) (PIBCA) nanoparticles (NPs) coated with Low Molecular Weight (LMW) chitosan (CS)- and glycol chitosan (GCS)-based thiomers as well as with the ...
TRAPANI, Giuseppe +4 more
core +1 more source
Non-ionic thiolated cyclodextrins — the next generation
International Journal of Nanomedicine, 2018 Ali Moghadam,1,2 Muhammad Ijaz,2,3 Mulazim Hussain Asim,2,4 Arshad Mahmood,2,5 Max Jelkmann,2 Barbara Matuszczak,6 Andreas Bernkop-Schnürch2 1Institute of Biotechnology, College of Agriculture, Shiraz University, Shiraz, Iran; 2Center for Chemistry
Moghadam A +6 more
doaj
, 2014 The aim of the present work was to compare the mucoadhesive and efflux pump P-glycoprotein (P-gp) interacting properties of chitosan (CS)- and glycolchitosan (GCS)-based thiomers and corresponding unmodified parent polymers.
Palazzo C +9 more
core +1 more source
, 2022 Aim: The aim of this study was the synthesis and evaluation of entirely S-protected thiolated hydroxyethylcellulose (HEC) with low and high viscosity, as well as thiolated poly-L-lysine (poly-L-Lys) used as dual-acting ionic as well as thiol-disulfide ...
Burcu Akkuş-Dağdeviren, Zeynep +6 more
core +1 more source
, 2020 The success of mucoadhesive drug delivery systems relies on the type of polymer used, which becomes adhesive naturally upon hydration. Intended polymers should be able to maintain prolonged contact with biological membranes, and to protect or cater the ...
Chakka Gopinath +2 more
core +1 more source
, 2018 Aim: Our aim was to inhibit trypanothione reductase (TR) and P-gp efflux pump of Leishmania by the use of thiolated polymers. Thus, increasing the intracellular accumulation and therapeutic effectiveness of antimonial compounds.
Sehreen Ashraf +8 more
core +1 more source
Carbohydrate Polymers / Thiolated chitosans: are Cys-Cys ligands key to the next generation?
, 2020 The potential of Cys-Cys ligands for the development of a novel type of S-protected thiomers was evaluated. S-protected thiomers chitosan-N-acetylcysteine-mercaptonicotinamide (CS-NAC-MNA) and chitosan-N-acetylcysteine-N-acetylcysteine (CS-NAC-NAC) were ...
Hupfauf, A. +5 more
core +1 more source
Mercaptonicotinic acid activated thiolated chitosan (MNA-TG-chitosan) to enable peptide oral delivery by opening cell tight junctions and enhancing transepithelial transport. [PDF]
Sci Rep, 2023 Pratap-Singh A +3 more
europepmc +1 more source
Classification of Tear Film Lipid Layer En Face Maps Obtained Using Optical Coherence Tomography and Their Correlation With Clinical Parameters. [PDF]
Cornea, 2023 Stegmann H +7 more
europepmc +1 more source
The Role of Mucoadhesion and Mucopenetration in the Immune Response Induced by Polymer-Based Mucosal Adjuvants. [PDF]
Polymers (Basel), 2023 Vasquez-Martínez N +4 more
europepmc +1 more source