Results 51 to 60 of about 28,515 (256)

Thiopental sodium loaded solid lipid nano-particles attenuates obesity-induced cardiac dysfunction and cardiac hypertrophy via inactivation of inflammatory pathway

Drug Delivery, 2020
This work evaluates solid lipid nanoparticles of thiopental sodium against obesity-induced cardiac dysfunction and hypertrophy and explores the possible mechanism of action.
Canzhan Zhu, Wanjing Li, Xinhong Wang, Jiahong Xue, Ling Zhao, Yafan Song, Tian Zhou, Mingjuan Zhang   +7 more
doaj   +1 more source

Effect of Thiopental on Ischemic Stroke in Rat Brain in Spontaneously Hypertensive Rats

Applied Bionics and Biomechanics, 2022
Motivation and Problem Statement. Thiopental is an anesthetic drug related to the condition of controlling the area of neurological contexts. This study is related to the analysis of effectiveness for the condition of thiopental application on ...
Lu You, Qian Zhao, JianYong Yan, Wen Li, Ye Yang, Chenguang Qin   +5 more
doaj   +1 more source

Prognostic factors and impact of management strategies for status epilepticus: The STEPPER study in the Emilia‐Romagna region, Italy

Epilepsia, Volume 66, Issue 3, Page 753-767, March 2025.
Abstract Objective The STEPPER (Status Epilepticus in Emilia‐Romagna) study aimed to investigate the clinical characteristics, prognostic factors, and treatment approaches of status epilepticus (SE) in adults of the Emilia‐Romagna region (ERR), Northern Italy.
Lidia Di Vito, Eleonora Matteo, Stefano Meletti, Corrado Zenesini, Giorgia Bernabè, Chiara Bomprezzi, Maria Chiara Casadio, Carlo Alberto Castioni, Edward Cesnik, Carlo Coniglio, Marco Currò‐Dossi, Patrizia De Massis, Elisa Fallica, Irene Florindo, Giada Giovannini, Maria Guarino, Elena Marchesi, Andrea Marudi, Elena Merli, Giulia Monti, Niccolò Orlandi, Elena Pasini, Daniela Passarelli, Rita Rinaldi, Romana Rizzi, Michele Romoli, Mario Santangelo, Valentina Tontini, Giulia Turchi, Mirco Volpini, Andrea Zini, Lucia Zinno, Roberto Michelucci, Luca Vignatelli, Paolo Tinuper, Francesca Bisulli, the STEPPER study group, Emanuele Saverio Cece, Fabio Nobili, Gabriele Ricci, Gloria Stoffella, Maria Tappatà, Stefania Testoni, Anna Zaniboni, Roberto D’Alessandro, Marco Zanello, Yerma Bartolini, Giovanni Bini, Maura Pugliatti, Francesca Ceccaroni, Chiara Leta, Claudia Giorgi, Edoardo Picetti, Alessandro Pignatti, Ilaria Naldi, Marco Russo, Anna Rita Guidi   +56 more
wiley   +1 more source

Rectal Thiopental versus Intramuscular Ketamine in Pediatric Procedural Sedation and Analgesia; a Randomized Clinical Trial

Archives of Academic Emergency Medicine, 2018
Introduction: Physicians frequently deal with procedures which require sedation of pediatric patients. Laceration repair is one of them. No study has been performed regarding the comparison between induction of sedation with sodium thiopental and ...
Reza Azizkhani, Mehrdad Esmailian, Azadeh shojaei, Keihan Golshani   +3 more
doaj   +1 more source

Inhibitory Effect of Thiopental on Ultra-rapid Delayed Rectifier K+ Current in H9c2 Cells

Journal of Pharmacological Sciences, 2005
Using the whole-cell voltage clamp technique, we investigated the effects of thiopental on membrane currents in H9c2 cells, a cell line derived from embryonic rat heart.
Hideki Suzuki, Nobuo Momoi, Tomoyuki Ono, Sachiko Maeda, Yayoi Shikama, Isao Matsuoka, Hitoshi Suzuki, Junko Kimura   +7 more
doaj  

Sedation Therapy in Intensive Care Units: Harnessing the Power of Antioxidants to Combat Oxidative Stress

Biomedicines, 2023
In critically ill patients requiring intensive care, increased oxidative stress plays an important role in pathogenesis. Sedatives are widely used for sedation in many of these patients. Some sedatives are known antioxidants.
Gen Inoue, Yuhei Ohtaki, Kazue Satoh, Yuki Odanaka, Akihito Katoh, Keisuke Suzuki, Yoshitake Tomita, Manabu Eiraku, Kazuki Kikuchi, Kouhei Harano, Masaharu Yagi, Naoki Uchida, Kenji Dohi   +12 more
doaj   +1 more source

A comparison of hemodynamic variations in induction of anesthesia and incidence of post operation nausea and vomiting with Propofol and Thiopental

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2002
Background and Objective: Propofol is one of the latest drugs for induction and maintenance of anesthesia. Nowadays the use of it, is increasing because of its fast onset, short effect duration, anti nausea and vomiting effect and post operation well ...
E Alijan Pour, SM Rabiei, P Amri Maleh, AA Moghadam Nia   +3 more
doaj  

Comparison of Ketamine-Propofol and Ketamine-Thiopental on Bispectral Index Values during Monitored Anesthesia Care (MAC) in Minor Traumatic Orthopedic Surgery; A Randomized, Double-Blind, Clinical Trial [PDF]

Bulletin of Emergency and Trauma, 2019
Objective: To compare the effects of ketamine-propofol and ketamine-thiopental on bispectral index values during monitored anesthesia care in minor orthopedic surgeries.Methods: This randomized double-blind clinical trial was performed on 90 patients ...
Afsaneh Nowroozi, Hanieh Kianipour, Houshang Taleby, Bijan Yazdi   +3 more
doaj   +1 more source

In Vivo Quantification of Creatine Kinase Kinetics in Mouse Brain Using 31P‐MRS at 7 T

NMR in Biomedicine, Volume 38, Issue 6, June 2025.
We demonstrate the feasibility of using 31P‐MRS to quantify creatine kinase activity in the mouse brain on preclinical 7‐T scanners. A 20% drop in respiration increased the apparent forward rate constant by 36%, likely due to altered pH and mitochondrial ATP production.
Mohamed Tachrount, Sean Smart, Jason Lerch, Antoine Cherix   +3 more
wiley   +1 more source

Colo‐Protective Effects of Pentoxifylline Alone or in Combination With Mesalamine in Colitis Through Sphingosine Kinase 1/Sphingosine 1 Phosphate, and Zonula Occuldin 1 Pathways: New Molecular Approach

Pharmacology Research &Perspectives, Volume 13, Issue 3, June 2025.
ABSTRACT Multiple signaling pathways have been implicated in the pathogenesis of ulcerative colitis (UC), including Sphingosine Kinase 1 (SPHK)/Sphingosine‐1‐Phosphate (S1P), AMP‐activated protein kinase (AMPK)/mammalian target of rapamycin (mTOR)/NLR family pyrin domain‐containing 3 (NLRP3), zonula occludens‐1 (ZO‐1), and signal transducer and ...
Fatemah A. Alherz, Mahmoud S. Abdallah, Esraa M. Mosalam, Mostafa M. Bahaa, Thanaa A. Elmasry, Mohamad A. El‐Gammal, Walaa A. Negm, AyaIbrahim Elberri, Nora Elshorbagi, Hend E. Abo Mansour, Amir O. Hamouda, Muhammed M. Salahuddin, Mohamed Yasser, Mamdouh Eldesoqui, Sarah Alrubia, Amsha S. Alsegiani, Eman El‐Khateeb, Mohamed Kh. ElMahdy, Eman Wahsh   +18 more
wiley   +1 more source