Results 31 to 40 of about 16,204 (217)

Comparison of cerebral effects of thiopental and propofol infusion in traumatic brain injured rats

Northwestern Medical Journal, 2022
Aim: Head trauma is a lethal, disabling, and pathological condition requiring long-term treatment and care. Thiopental and propofol infusions are frequently used for sedation in the intensive care unit (ICU).
Yıldıray Kılıccıoğlu, İsa Yıldız, Hamit Yoldaş, İbrahim Karagöz, Buket Kin Tekce, Ayhan Çetinkaya, Murat Bilgi, Abdullah Demirhan, Aysel Kükner   +8 more
doaj   +1 more source

Detection of potential effects of orphenadrine upon anesthesia with propofol and/or thiopental in mice [PDF]

Iraqi Journal of Veterinary Sciences
Orphenadrine is an anticholinergic drug used in clinics as a muscle relaxant. It acts on several receptors, including muscarinic, histaminic, and NMDA. This study aimed to evaluate the effect of pretreatment with orphenadrine on the anesthesia indices of
Yasser M. Albadrany, Ahmed S. Naser, Khalid A. Shaban   +2 more
doaj   +1 more source

Thiopental Elevates Steady-State Levels of Intracellular Ca2+ and Zn2+ in Rat Thymic Lymphocytes: Toxicity test of thiopental on rat thymic lymphocytes

, 2020
Thiopental is an ultra-short-acting barbiturate and has been used commonly in the induction phase of general anesthesia. However, the toxic effect of thiopental is not completely clear.?The effect of thiopental on intracellular Ca2+ ([Ca2+]i) levels was ...
Mizobuchi, Mizuki, Kamemura, Norio, Oyama, Keisuke, Kanematsu, Naoki, Ueno, Shinya, Ishidoh, Kazumi   +5 more
core   +1 more source

Cardioprotection via modulation of calcium homeostasis by thiopental in hypoxia-reoxygenated neonatal rat cardiomyocytes [PDF]

, 2020
Purpose: Ca2+ homeostasis plays an important role in myocardial cell injury induced by hypoxia-reoxygenation, and prevention of intracellular Ca2+ overload is key to cardioprotection.
김현수
core   +2 more sources

Incidence of adverse events for procedural sedation and analgesia for cardioversion using thiopental in elderly patients: a multicenter prospective observational study

Acute Medicine & Surgery, 2023
Aim The incidence and characteristics of thiopental‐related adverse events (AEs) in elderly patients during procedural sedation and analgesia (PSA) have not been well studied.
Minoru Hayashi, Tatsuya Norii, Danielle Albright, Cameron Crandall   +3 more
doaj   +1 more source

Neuroprotektive Mechanismen von Thiopental

, 2016
In der vorliegenden Arbeit wurden molekulare neuroprotektive Eigenschaften von Thiopental untersucht. Unsere Beobachtungen belegen, dass Thiopental die Aktivierung von Calcineurin, dem nukleären Faktor aktivierter T-Zellen (NFAT) und der Caspase-3 hemmt ...
Pietsch, Christine
core   +1 more source

Thiopental studies

, 2016
A literature review of recently published papers using thiopental as part of the anesthetic ...
Smith, Brett B., Anthony G. Messina (3272307), Ward, Marshall J., Dan Vezina (3272406), Michael Wang (265591), Chase C. Wilker (3272304), Wilker, Chase C., Pace, Nathan, Nathan Pace (3272313), Wang, Michael, Marshall J. Ward (3272310), Messina, Anthony G., Vezina, Dan, Brett B. Smith (3272301)   +13 more
core   +1 more source

The dosage of thiopental as pharmacological cerebral protection during non-shunt carotid endarterectomy: A retrospective study [version 3; peer review: 2 approved]

F1000Research, 2023
Background Thiopental has been used as a pharmacological cerebral protection strategy during carotid endarterectomy surgeries. However, the optimal dosage required to induce burst suppression on the electroencephalogram (EEG) remains unknown.
Pimwan Sookplung, Pathomporn Suchartwatnachai, Phuping Akavipat   +2 more
doaj   +1 more source

Thiopental induces AMPK autophosphorylation.

, 2013
Cells were treated with 10 µM –2 mM thiopental for 6 h (A) or with 0.5 mM thiopental for 10 min to 12 h (B) and analyzed by immunoblotting with an anti-human phospho-AMPK threonine 172 antibody (upper blots) or an AMPK antibody that detects endogenous ...
Cornelius Lehane (475275), Karl M. Strosing (475278), Simone Zenker (475277), Hartmut Buerkle (131054), Anika Erxleben (475280), Bernd Heimrich (475281), Christian I. Schwer (131043), Sashko Spassov (475279), Matjaz Humar (475282), Timo Guelzow (475276)   +9 more
core   +1 more source

Thiopental inhibits global protein synthesis by repression of eukaryotic elongation factor 2 and protects from hypoxic neuronal cell death. [PDF]

PLoS ONE, 2013
Ischemic and traumatic brain injury is associated with increased risk for death and disability. The inhibition of penumbral tissue damage has been recognized as a target for therapeutic intervention, because cellular injury evolves progressively upon ATP-
Christian I Schwer, Cornelius Lehane, Timo Guelzow, Simone Zenker, Karl M Strosing, Sashko Spassov, Anika Erxleben, Bernd Heimrich, Hartmut Buerkle, Matjaz Humar   +9 more
doaj   +1 more source