The Effects of Propofol and Thiopental on Nitric Oxide Production and Release in Erythrocytes [PDF]
Background: Hypotension is a common adverse effect associated with the use of propofol and sodium thiopental. The objective of this study was to examine the impact of thiopental and propofol on erythrocyte (RBC) nitric oxide (NO) synthase activity and ...
Ulku Arslan +11 more
doaj +3 more sources
Thiopental Elevates Steady-State Levels of Intracellular Ca2+ and Zn2+ in Rat Thymic Lymphocytes
Thiopental is an ultra-short-acting barbiturate and has been used commonly in the induction phase of general anesthesia. However, the toxic effect of thiopental is not completely clear.?The effect of thiopental on intracellular Ca2+ ([Ca2+]i) levels was ...
Norio Kamemura +5 more
doaj +2 more sources
Thiopental Versus Propofol in Combination with Remifentanil for Successful Classic Laryngeal Mask Airway Insertion: A Prospective, Randomised, Double-Blind Trial [PDF]
Background: Remifentanil, an ultra-short-acting μ-receptor agonist, is used with propofol or thiopental for tracheal intubation without muscle relaxants.
Mert Akan +8 more
doaj +2 more sources
The impact of ketamine and thiopental anesthesia on ultraweak photon emission and oxidative-nitrosative stress in rat brains [PDF]
Anesthetics such as ketamine and thiopental, commonly used for inducing unconsciousness, have distinct effects on neuronal activity, metabolism, and cardiovascular and respiratory systems. Ketamine increases heart rate and blood pressure while preserving
Mahdi Khorsand Ghaffari +9 more
doaj +2 more sources
Comparison of the Effects of Propofol–Dexmedetomidine and Thiopental–Dexmedetomidine Combinations on the Success of Classical Laryngeal Mask Airway Insertions, Hemodynamic Responses, and Pharyngolaryngeal Morbidity [PDF]
Background and Objectives: Dexmedetomidine is a potent selective α2 receptor agonist with analgesic and sedative effects. Many reports indicate that compared to fentanyl, the combination of dexmedetomidine with propofol provides comparably acceptable ...
Mensure Çakırgöz +7 more
doaj +2 more sources
The Effect of Adding Remifentanil to Thiopental for Anaesthesia Induction on the Success of Classic Laryngeal Mask Airway Insertion: A Randomised Double-Blind Clinical Trial [PDF]
Background: Remifentanil, an ultra-short-acting µ-receptor agonist, is used with propofol for optimal laryngeal mask airway (LMA) insertion. However, no studies have assessed its effects when combined with thiopental on LMA conditions.
Mensure Çakırgöz +7 more
doaj +2 more sources
We investigated the acute effects of thiopental anesthesia (4 mg/100 g, i.v.) on plasma glucose, insulin, triacylglycerol, and prolactin levels in rats treated with bromocriptine (BR) (0.4 mg/100 g body wt, i.p., for two weeks).
Antônio Ribeiro de Oliveira, Jr. +7 more
doaj +2 more sources
In a randomized study we compared postoperative pain and analgesic requirement in patients who underwent elective cesarean section under general anesthesia induced with Thiopental 4 mg/kg (N=25) or Ketamin 1 mg/kg (N=25).
A.R.Kholdbarin (M.D), P.Soltani (M.D)
doaj +1 more source
Propofol-Related Infusion Syndrome in Paediatrics-Cautious Consideration or Considered Caution? Case Report. [PDF]
Journal of Paediatrics and Child Health, Volume 62, Issue 6, Page 1075-1080, June 2026.
Stokes MA +5 more
europepmc +2 more sources
Gallic Acid-Mediated Enhancement of Diazepam-Induced Sedation via GABA<sub>A</sub> Receptor Modulation: In Vivo and In Silico Evaluation. [PDF]
Gallic acid (GA) dose‐dependently reduced sleep latency and prolonged sleep duration in thiopental sodium‐induced mice, with synergistic effects when combined with diazepam. Molecular docking revealed GA's higher binding affinity (−9.8 kcal/mol) to GABAA receptor (α1 and β2 subunits) than diazepam (−8.4 kcal/mol), suggesting GABAergic potential ...
Yana NT +14 more
europepmc +2 more sources

