Results 21 to 30 of about 26,201 (218)

Inhalational or total intravenous anaesthesia: is total intravenous anaesthesia useful and are there economic benefits? [PDF]

, 2011
PURPOSE OF REVIEW: The comparison of inhalational and intravenous anaesthesia has been the subject of many controlled trials and meta-analyses. These reported diverse endpoints typically including measures of the speed and quality of induction of ...
Holmes, KA, Sneyd, JR
core   +1 more source

Detection of potential effects of orphenadrine upon anesthesia with propofol and/or thiopental in mice [PDF]

Iraqi Journal of Veterinary Sciences
Orphenadrine is an anticholinergic drug used in clinics as a muscle relaxant. It acts on several receptors, including muscarinic, histaminic, and NMDA. This study aimed to evaluate the effect of pretreatment with orphenadrine on the anesthesia indices of
Yasser M. Albadrany, Ahmed S. Naser, Khalid A. Shaban   +2 more
doaj   +1 more source

Abietic Acid Enhances the Sedative Activity of Diazepam: In vivo Approach along with Receptor Binding Affinity and Molecular Interaction with the GABAergic System. [PDF]

ChemistryOpen
Abietic acid (AA) reveals potent sedative potential by expressing fast sleeping onset and increased sleeping duration compare to the control group in thiopental sodium induced sleeping mice. The compound also exhibited notable binding affinity (–7.9 kcal/mol) toward GABAA receptors.
Afroz M, Hasan R, Khatun MM, Tito MH, Shadin M, Chakma R, Asiri M, Altemani FH, Altemani AH, Bhuia MS, Islam MT.   +10 more
europepmc   +2 more sources

Diclofenac Prolongs Repolarization in Ventricular Muscle with Impaired Repolarization Reserve [PDF]

, 2012
Background: The aim of the present work was to characterize the electrophysiological effects of the non-steroidal anti- inflammatory drug diclofenac and to study the possible proarrhythmic potency of the drug in ventricular muscle.
A Farkas, A Peretz, A Varró, A Varró, A Varró, AJ Batey, Andrea Barbuti, András Varró, Attila Kristóf, B Girennavar, B Scheidel, C Bombardier, C Lengyel, C Lengyel, CL Lawrence, Cs Lengyel, D Corrado, DM Roden, DM Roden, DM Roden, E Coraboeuf, EL Fosbøl, FI Al-Jenoobi, G Hart, HA Bird, István Baczkó, István Koncz, JH Lin, JJ Duncan, Julius Gy Papp, L Carlsson, L Virág, LI Brueggemann, LL von Moltke, LY Liu, László Virág, M Hidaka, M Niemi, MA Vos, N Jost, Norbert Jost, OV Yarishkin, P McGettigan, PG Volders, Péter Biliczki, R Bort, R Varkevisser, S Trelle, T Christ, Tamás Szél, Viktor Juhász, WF Huang, WF Huang, XW Fei, Y Lu, Zoltán Husti, Zsófia Kohajda   +56 more
core   +5 more sources

Incidence of adverse events for procedural sedation and analgesia for cardioversion using thiopental in elderly patients: a multicenter prospective observational study

Acute Medicine & Surgery, 2023
Aim The incidence and characteristics of thiopental‐related adverse events (AEs) in elderly patients during procedural sedation and analgesia (PSA) have not been well studied.
Minoru Hayashi, Tatsuya Norii, Danielle Albright, Cameron Crandall   +3 more
doaj   +1 more source

Imaging Microglial/Macrophage Activation in Spinal Cords of Experimental Autoimmune Encephalomyelitis Rats by Positron Emission Tomography Using the Mitochondrial 18kDa Translocator Protein Radioligand [18F]DPA-714 [PDF]

, 2012
Multiple sclerosis (MS) is an inflammatory demyelinating disease of the CNS. Activated microglia/macrophages play a key role in the immunopathogenesis of MS and its corresponding animal models, experimental autoimmune encephalomyelitis (EAE).
Abourbeh, Galith, Boisgard, Raphael, Brulon, Vincent, Dollé, Frédéric, Dubois, Albertine, Fontyn, Yoann, Maroy, Renaud, Tavitian, Bertrand, Thézé, Benoit   +8 more
core   +2 more sources

The dosage of thiopental as pharmacological cerebral protection during non-shunt carotid endarterectomy: A retrospective study [version 3; peer review: 2 approved]

F1000Research, 2023
Background Thiopental has been used as a pharmacological cerebral protection strategy during carotid endarterectomy surgeries. However, the optimal dosage required to induce burst suppression on the electroencephalogram (EEG) remains unknown.
Pimwan Sookplung, Pathomporn Suchartwatnachai, Phuping Akavipat   +2 more
doaj   +1 more source

Thiopental inhibits global protein synthesis by repression of eukaryotic elongation factor 2 and protects from hypoxic neuronal cell death. [PDF]

PLoS ONE, 2013
Ischemic and traumatic brain injury is associated with increased risk for death and disability. The inhibition of penumbral tissue damage has been recognized as a target for therapeutic intervention, because cellular injury evolves progressively upon ATP-
Christian I Schwer, Cornelius Lehane, Timo Guelzow, Simone Zenker, Karl M Strosing, Sashko Spassov, Anika Erxleben, Bernd Heimrich, Hartmut Buerkle, Matjaz Humar   +9 more
doaj   +1 more source

The role of setting for ketamine abuse: clinical and preclinical evidence [PDF]

, 2012
Drug abuse is often seen as a unitary phenomenon, partly as a result of the discovery over the past three decades of shared mechanisms of action for addictive substances. Yet the pattern of drug taking is often very different from drug to drug.
Sprenger, Stewart, Tellier, Topp, Triffleman, Vollenweider, Vollenweider, Weir, White   +8 more
core   +1 more source

Oral Chloral Hydrate Compare with Rectal Thiopental in Pediatric Procedural Sedation and Analgesia; a Randomized Clinical Trial

Archives of Academic Emergency Medicine, 2018
Introduction: The increasing use of diagnostic imaging in pediatric medicine has resulted in growing need for procedural sedation and analgesia (PSA) to minimize motion artifacts during procedures.
Reza Azizkhani, Soheila Kanani, Ali Sharifi, Keihan Golshani, Babak Masoumi, Omid Ahmadi   +5 more
doaj   +1 more source