Results 1 to 10 of about 39,833 (328)

Assembly strategy for thieno[3,2-b]thiophenes via a disulfide intermediate derived from 3-nitrothiophene-2,5-dicarboxylate [PDF]

Beilstein Journal of Organic Chemistry
A versatile synthetic route to thieno[3,2-b]thiophenes was elaborated from dimethyl 3-nitrothiophene-2,5-dicarboxylate. Nucleophilic substitution of the nitro group with sulfur nucleophiles, including thioacetate or disulfide anions as well as ...
Roman A. Irgashev
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Direct dehydrocoupling facilitates efficient thiophene anchoring on silicon surfaces [PDF]

Nature Communications
Silicon is a cornerstone material in electronics and photovoltaics due to its abundance, tunable semiconducting properties, and chemical versatility. Direct anchoring of thiophenes, with their highly delocalized aromatic backbones, onto silicon surfaces ...
Jingpeng Li, Meiyu Zhang, Wenxuan Li, Zhongshu Li, Tingshun Zhu, Zhenyu Yang   +5 more
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Echinops as a Source of Bioactive Compounds—A Systematic Review [PDF]

Pharmaceuticals
Background: Echinops is a genus of spiny, herbaceous perennials in the Asteraceae family, known for its distinct morphology and broad pharmacological potential.
Simona Ivanova, Alexandra Ivanova, Mina Todorova, Vera Gledacheva, Stoyanka Nikolova   +4 more
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Integrated Extraction Optimization and HPLC‐based Quality Evaluation of Thiophenes from Tagetes erecta Roots [PDF]

Analytical Science Advances
Tagetes erecta L. is widely studied for its flower‐derived lutein, which is known for promoting eye health. However, its roots contain uniquely thiophenes—absent from the flowers and leaves—which exhibit valuable bioactivity.
Shuo Tian, Sainan Li, Jisu Park, Jong‐Sup Bae, MinKyun Na   +4 more
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Triggering redox activity in a thiophene compound: radical stabilization and coordination chemistry [PDF]

, 2006
The synthesis, metalation, and redox properties of an acyclic bis(iminothienyl)methene L− are presented. This π-conjugated anion displays pronounced redox activity, undergoing facile one-electron oxidation to the acyclic, metal-free, neutral radical L ...
Davison, Gray, Gray, Schrauzer, Eisenberg, Sproules, Lyons, Kaim, Krężel, Jacquet, Huang, Broere, Greenhalgh, Luca, Munhá, Lyaskovskyy, Praneeth, Kaim, Chirik, Chirik, Annibale, Pankhurst, Pankhurst, Kochem, Reddy, Schweyen, Yoshida, Tanaka, Claessens, Hennessy, Loudet, Kaszyński, Chatterjee, Rasmussen, Gopalakrishna, Wakamiya, Tabakovic, d'Oro, Singh, Kawase, Davenport, Kia, Chen, Doshi, Latos-Grazynski, Lucas, Lane   +46 more
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Silica gel-assisted synthesis of benzo[b]thiophenes from o-(alkylsulfanyl)(ethynyl)benzenes

Results in Chemistry, 2022
A variety of 2-substituted benzo[b]thiophenes were prepared from o-(alkylsulfanyl)(ethynyl)benzenes in the presence of silica gel under thermal conditions. Tertiary alkyl-substituted sulfanyl derivatives gave good results.
Kozo Toyota, Hiroki Tanaka, Taisei Hanagasaki   +2 more
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The Ethnopharmacological Uses, Metabolite Diversity, and Bioactivity of Rhaponticum uniflorum (Leuzea uniflora): A Comprehensive Review

Biomolecules, 2022
Rhaponticum uniflorum (L.) DC. (syn. Leuzea uniflora (L.) Holub) is a plant species of the Compositae (Asteraceae) family that is widely used in Asian traditional medicines in China, Siberia, and Mongolia as an anti-inflammatory and stimulant remedy ...
Daniil N. Olennikov
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Synthetic thiophenes induce chromosomal damage and trigger apoptosis in human cancer cell lines

European Journal of Medicinal Chemistry Reports, 2022
Thiophenes are heterocyclic compounds containing a five-membered ring with sulphur as the heteroatom. This class of substances has been shown to have several biological activities, including specific anti-proliferative effects against some cancer cell ...
Filipe N. Franco, Júlia T. Oliveira, Kimberly B. Tecchio, Flaviana A. Santos, Moacyr J.B.M. Rêgo, Francisco J.B. Mendonça-Júnior, Maira G.R. Pitta, Michelly C. Pereira, Rosy I.M.A. Ribeiro, Vanessa J.S.V. Santos, Fabio V. Santos   +10 more
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Synthesis, Molecular Docking Study, and Cytotoxic Activity against MCF Cells of New Thiazole–Thiophene Scaffolds

Molecules, 2022
Investigating novel compounds that may be useful in designing new, less toxic, selective, and potent breast anticancer agents is still the main challenge for medicinal chemists.
Sobhi M. Gomha, Sayed M. Riyadh, Bader Huwaimel, Mohie E. M. Zayed, Magda H. Abdellattif   +4 more
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Thiophenes—Naturally Occurring Plant Metabolites: Biological Activities and In Silico Evaluation of Their Potential as Cathepsin D Inhibitors

Plants, 2022
Naturally, thiophenes represent a small family of natural metabolites featured by one to five thiophene rings. Numerous plant species belonging to the family Asteraceae commonly produce thiophenes.
Sabrin R. M. Ibrahim, Abdelsattar M. Omar, Alaa A. Bagalagel, Reem M. Diri, Ahmad O. Noor, Diena M. Almasri, Shaimaa G. A. Mohamed, Gamal A. Mohamed   +7 more
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