Results 141 to 150 of about 7,079 (242)

Thiopurine methyltransferase genotype and activity cannot predict outcomes of azathioprine maintenance therapy for antineutrophil cytoplasmic antibody associated vasculitis: A retrospective cohort study. [PDF]

PLoS One, 2018
Hessels AC, Rutgers A, Sanders JSF, Stegeman CA.   +3 more
europepmc   +1 more source

Thiopurine S-Methyltransferase Polymorphisms in Korean Dermatologic Patients [PDF]

, 2017
Minseok Lee, Jimyung Seo, Dongsik Bang, Do Young ‍Kim   +3 more
openalex   +1 more source

The impact of thiopurine-S-methyltransferase genotype on the adverse drug reactions to azathioprine in patients with inflammatory bowel diseases

, 2013
Tibor Hlavatý, M Bátovský, D. Balakova, Igor Pav, Peter Celec, M. Gregus, Mária Zakuciová, Milan Hlista, Magda Horáková, B. Desatova, T. Köller, Jozef Tóth, Ľudevít Kádaši, M Huorka   +13 more
openalex   +2 more sources

Thiopurine methyltransferase and treatment outcome in the UK acute lymphoblastic leukaemia trial ALL2003. [PDF]

Br J Haematol, 2015
Lennard L, Cartwright CS, Wade R, Vora A.   +3 more
europepmc   +1 more source

Rapid, Long-Range Molecular Haplotyping of Thiopurine S-Methyltransferase (TPMT*) *3A, *3B, and *3C [PDF]

, 2004
Nicolas von Ahsen, Victor W. Armstrong, Michael Oellerich   +2 more
openalex   +1 more source

Thiopurine methyltransferase genotype and thiopurine S-methyltransferase activity in Greek children with inflammatory bowel disease.

Annals of gastroenterology
Azathioprine (AZA) and 6-mercaptopurine (6MP) are used in the treatment of pediatric inflammatory bowel disease (IBD). Genetic variations in thiopurine S-methyltranfarase (TPMT) gene have been correlated with enzyme activity and with the occurrence of adverse events to AZA and 6MP.
Muaria, Gazouli, Ioanna, Pachoula, Ioanna, Panayotou, Georgios, Chouliaras, Nicholas P, Anagnou, George, Chroussos, Eleftheria, Roma   +6 more
openaire   +1 more source

P651 Identification of new genetic variants related to thiopurine-induced myelotoxicity in inflammatory bowel disease (IBD) patients with normal thiopurines-methyltransferase (TPMT): a genome-wide association study [PDF]

, 2014
María Chaparro, Anna González‐Neira, Manuel Román, Guillermo Pita, Teresa Cabaleiro, D. Herrero, Belén Herráez, Ricardo Blanco, Carlos Taxonera, Pilar López Serrano, Pilar Martínez-Montiel, Isabel Vera, Fernando Bermejo, Antonio López-San Román, Francisco Abad‐Santos, Javier P. Gisbert   +15 more
openalex   +1 more source

Transcriptome analysis reveals involvement of thiopurine S-methyltransferase in oxidation-reduction processes

, 2023
Alenka Šmid, Miha Štajdohar, Miha Milek, Dunja Urbančič, Nataša Karas Kuželički, Riin Tamm, Andres Metspalu, Irena Mlinarič‐Raščan   +7 more
openalex   +1 more source

Assessment of thiopurine methyltransferase activity in patients prescribed azathioprine or other thiopurine-based drugs.

, 2010
Ronald A. Booth, Mohammed T Ansari, Andrea C. Tricco, Evelin Loit, Laura Weeks, Steve Doucette, Becky Skidmore, Jeffrey S. Hoch, Sophia Tsouros, Margaret Sears, Richmond Sy, Jacob Karsh, Suja Mani, James Galipeau, Alexander Yurkiewich, Raymond Daniel, Alexander Tsertsvadze, Fatemeh Yazdi   +17 more
openalex   +1 more source

Pharmacogenetic Analysis of TPMT and NUDT15 in a European Pediatric Cohort with IBD and Autoimmune Diseases: Frequency Data and Clinical Relevance. [PDF]

Genes (Basel)
Pau A, Galliano I, Ponte A, Clemente A, Dini M, Calvi C, Montanari P, Pizzol A, Gambarino S, Calvo PL, Bergallo M.   +10 more
europepmc   +1 more source