Results 211 to 220 of about 206,003 (304)

Use of biomolecular emulator for characterizing flexible proteins by small‐angle x‐ray scattering

Protein Science, Volume 35, Issue 6, June 2026.
Abstract Flexible proteins populate heterogeneous conformational ensembles that are essential for their function. Small‐angle x‐ray scattering (SAXS) is widely used to study protein structure in solution and to characterize conformational heterogeneity.
Yoni Haitin, Bar Manori, Moshe Giladi
wiley   +1 more source

Whole genome sequence analysis of <i>Bifidobacterium animalis</i> subsp. <i>lactis</i> KL101 and comparative genomics with BB12. [PDF]

J Anim Sci Technol
Kim K, Lee J, Kang SJ, Oh S.
europepmc   +1 more source

The Antipsychotic Aripiprazole Induces Cytotoxicity in Bladder Cancer Cells While Preserving Urothelial and Bladder Function

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
Current bladder cancer therapies can cause toxicity and bladder dysfunction. Brief intravesical‐like aripiprazole exposure reduced bladder cancer cell viability and was associated with redox stress and caspase‐3 activation, while ex vivo findings suggested preserved bladder structure and function, warranting further investigation as a potential ...
Liam A. O'Callaghan, Katie Powell, Russ Chess‐Williams, Catherine McDermott   +3 more
wiley   +1 more source

Aberrant DNMTs Promote TXNIP Upregulation and Ovarian Fibrosis in PCOS. [PDF]

FASEB J
Weng Y, Shangguan L, Shen Q, Zhu Z, Zhang Y, Zhang J, Yan G, Shen S, Xiang Z, Ruan J, Wen Y, Wang D, Wang Y.   +12 more
europepmc   +1 more source

Harnessing Trace Elements: Novel Radiosensitization Strategies for Enhanced Cancer Radiotherapy

Rare Metals, Volume 45, Issue 6, June 2026.
ABSTRACT Radiotherapy (RT) is one of the core methods of comprehensive cancer treatment. Globally, more than 40% of cancer patients rely on radiotherapy to achieve tumor control, cure or palliative relief. However, radiation resistance, immunosuppression and normal tissue injury limit its clinical application.
Yuhuan Zhang, Yizhi Ge, Hongguang Xiang, Ji Liu, Yu Tian, Yan Shen, Dan Zong   +6 more
wiley   +1 more source

Noise‐Induced Hearing Loss: From Pathological Mechanisms to Therapeutic Interventions

Sensory Neuroscience, Volume 2, Issue 2, June 2026.
ABSTRACT Noise‐induced hearing loss (NIHL), a significant non‐genetic form of hearing impairment, is primarily managed through the use of hearing aids and cochlear implants. However, the fundamental pathological mechanisms underlying NIHL remain inadequately addressed.
Shiqi Huang, Yu Xiao, Jiaxin Liu, Wen Jiang, Weiwei Shi, Hanbing Zhang, Xiaolong Fu, Yunhao Wu   +7 more
wiley   +1 more source

A universal cis-proline lock defines catalysis in thioredoxin-fold enzymes. [PDF]

Commun Biol
Cunliffe T, Wang G, Penning S, Subedi P, Totsika M, Paxman JJ, Heras B.   +6 more
europepmc   +1 more source

Catcher Domains as Multifunctional Fusion Modules for Soluble Expression, Covalent Coupling, and Spatial Organization of Recombinant Proteins

Small Science, Volume 6, Issue 6, June 2026.
Catcher domains function as highly versatile fusion tags that simultaneously enhance soluble protein expression and enable modular protein assembly. Spontaneous, irreversible covalent coupling by Catcher‐Tag pairs provides a platform for downstream modular engineering, enabling oriented enzyme immobilization, protein polymerization, and selective ...
Ruxia Fan, Xing Wan, Safoorah Khanum, Juhani P. Jokio, Nea B. Möttönen, Miia R. Mäkelä, A. Sesilja Aranko   +6 more
wiley   +1 more source

Inflammation and RONS Dysregulation by Redox Enzymes as Mechanistic Links in HIV-1-Cancer Comorbidity. [PDF]

Pathogens
Ang CG, Eyunni S, Chaiken IM.
europepmc   +1 more source