Low salivary thioredoxin-1 levels in periodontitis. [PDF]
Lorente L +9 more
europepmc +1 more source
Application of a novel LC-MS-based proteomic workflow for host cell protein monitoring and risk control in biotherapeutics. [PDF]
Yu X +6 more
europepmc +1 more source
ABSTRACT Extracellular vesicles (EVs) are key mediators of intercellular communication, enabling trans‐kingdom exchange of proteins, nucleic acids, lipids, and metabolites. In Giardia duodenalis, EVs contribute to parasite survival, host–pathogen interactions, and immune modulation.
Corral‐Ruiz Gerardo +9 more
wiley +1 more source
Exploring the neuroprotective potential of ligustrazine: a preclinical meta-analysis and machine learning perspective on cerebral ischemia-reperfusion injury. [PDF]
Tu L +5 more
europepmc +1 more source
The competitive interplay of 12-oxophytodienoic acid (OPDA), protein thiols, and glutathione. [PDF]
12‐Oxophytodienoic acid (OPDA) is a phytohormone involved in plant growth and stress defense. Due to its cyclopentenone moiety, OPDA can form Michael adducts with thiol‐containing compounds such as glutathione and cysteine residues of proteins, resulting in alterations of the cellular redox regulatory network.
Knieper M +8 more
europepmc +2 more sources
Acetate‐Linked Energy Metabolism as a Determinant of Early Haemophilus influenzae Infection Fitness
The Pta–AckA pathway is critical for Haemophilus influenzae energy generation, metabolic homeostasis, stress resistance, and intracellular colonization, highlighting its potential as a target for management of H. influenzae infections.
Marufa Nasreen +8 more
wiley +1 more source
The Role of Neutrophils and NETosis in Diseases: The Implications for Therapy
Neutrophils secrete cytokines, express specific surface proteins, increase or decrease in cell count, and their ratio to lymphocyte count can be used as biomarkers to characterize collective status and disease progression. Neutrophils can monitor and track the body's health status, “Wei Bing” status, disease status, and different times of disease ...
Zhen Ma +6 more
wiley +1 more source
Catalpol ameliorates diabetic retinal vascular endothelial injury by suppressing NLRP3 inflammasome <i>via</i> targeting METTL3-m<sup>6</sup>A modification. [PDF]
Liu JY +5 more
europepmc +1 more source
Redox Regulation and Oxidative Stress in Health and Disease: Mechanisms and Therapeutic Targeting
Reactive species serve crucial roles which are tightly regulated in both physiological as well as disease states. At physiological levels, these species are integral to redox signaling, while uncontrolled redox promotes disease pathology. This review examines the dysregulation of these processes.
Mohammad Hossein Azadi +2 more
wiley +1 more source

