Results 81 to 90 of about 197,748 (297)

Natural product based inhibitors of the thioredoxin–thioredoxin reductase system

open access: yesOrg. Biomol. Chem., 2004
Spiroketal naphthodecalins are readily assembled by Barton's base mediated Ullmann binaphthyl ether coupling, Dakin reactions and hypervalent iodine spirocyclization. The core structures can be further diversified by enone addition and Stille coupling reactions.
Wipf, Peter   +6 more
openaire   +4 more sources

Mortality risk stratification for Takotsubo syndrome: Evaluating CRP measurement alongside the InterTAK prognostic score

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1427-1436, April 2025.
Abstract Background and objectives Initially described as a benign acute cardiomyopathy, Takotsubo syndrome has been linked to elevated mortality rates. Emerging evidence suggests that unresolved myocardial inflammation may contribute to this adverse prognosis.
Loïc Faucher   +12 more
wiley   +1 more source

Dissecting the integrative antioxidant and redox systems in plant mitochondria. Effect of stress and S-nitrosylation.

open access: yesFrontiers in Plant Science, 2013
Mitochondrial respiration provides the energy needed to drive metabolic and transport processes in cells. Mitochondria are a significant site of reactive oxygen species (ROS) production in plant cells, and redox-system components obey fine regulation ...
Juan José Lázaro   +7 more
doaj   +1 more source

Synthesis of Unsymmetric Bis(heteroaryl) Selenides by Rhodium‐Catalyzed Exchange Reaction of Heteroaryl Fluorides and Ethers Using Se‐Heteroaryl Carboselenoates

open access: yesEuropean Journal of Organic Chemistry, EarlyView.
Various unsymmetric bis(heteroaryl) selenides are synthesized by the rhodium‐catalyzed exchange reaction of heteroaryl fluorides and ethers with Se‐heteroaryl 1‐adamatanecarboselenoates. The synthetic method is applicable to a broad range of five‐ and six‐membered heteroaryl derivatives and provides compounds containing multiple heteroatoms.
Masana Yazaki   +3 more
wiley   +1 more source

Identification of novel molecular candidates for fatty liver in the hyperlipidemic mouse model, HcB19

open access: yesJournal of Lipid Research, 2004
The inbred HcB19 mouse strain expresses a truncated form of thioredoxin interacting protein and is phenotypically characterized by fatty liver and elevated plasma triglycerides and VLDL.
Marleen M.J. van Greevenbroek   +2 more
doaj   +1 more source

Peroxiredoxins and NADPH-Dependent Thioredoxin Systems in the Model Legume Lotus japonicus    [PDF]

open access: hybrid, 2011
Alejandro Tovar‐Méndez   +8 more
openalex   +1 more source

Comparative Effects of Three Microbial Starter Cultures on the Physicochemical and Sensory Quality of Fermented Sausages

open access: yesFood Bioengineering, EarlyView.
ABSTRACT This study innovatively links specific microbial compositions of commercial starter cultures to the evolution of key odorant and taste‐active amino acids, revealing the underlying mechanisms behind distinct flavor profiles. Three microbial starter cultures—Saccharomyces cerevisiae (SC), Scarlet (ST), and Roxaane LC (LC), were added to sausages,
Lili Ji   +7 more
wiley   +1 more source

Selenium‐Containing Tea‐Derived Peptides Activate Alcohol Dehydrogenase and Ameliorate Alcohol‐Induced Liver Injury by Modulating Oxidative Stress Homeostasis

open access: yesFood Frontiers, EarlyView.
The graphical abstract summarizes the experimental workflow: (1) Preparation of selenium‐containing tea‐derived peptides (TSE‐PP) guided by ADH activation; (2) Purification and LC‐MS/MS identification of selenium‐modified peptides; (3) Molecular docking to reveal peptide‐ADH interactions; (4) Evaluation of hangover‐alleviating and hepatoprotective ...
Lixia Zan   +7 more
wiley   +1 more source

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

open access: yesInterdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui   +12 more
wiley   +1 more source

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