Results 131 to 140 of about 8,012 (300)

(Poly)phenols: Mechanisms of action and efficacy of contemporary supplements for exercise recovery and performance

Experimental Physiology, EarlyView.
Abstract (Poly)phenols are a diverse group of bioactive chemical compounds present in a wide range of plant‐ and animal‐based foods. Several thousands of (poly)phenols exist; many have potent biological effects, most notably antioxidant, anti‐inflammatory and vasodilatory.
Glyn Howatson, Tom Clifford
wiley   +1 more source

Mitochondrial Ca2+ uniporter haploinsufficiency leads to sexually dimorphic redox imbalance and metabolic remodelling in the mouse brain

The Journal of Physiology, EarlyView.
Abstract figure legend The genetic inactivation of one Mcu allele leads to sex‐specific changes in neuronal function in adult mice, that is, the firing of action potentials and the relationship between cytosolic and mitochondrial Ca2+ levels. The ability to produce NAD(P)H by stimulated neural tissue is largely preserved in male mice but delayed in ...
Jenna Gray, Girish Halemirle, Beatriz Ferrán, Hadyn Rose, Traci L. Redwine, Sophia Pham, Bo Hagy, Atul Pranay, Jennifer Giorgione, Stacy A. Hussong, Veronica Galvan, Kenneth Humphries, Holly Van Remmen, Mike Kinter, William E. Sonntag, Pankaj K. Singh, Carlos Manlio Díaz‐García   +16 more
wiley   +1 more source

Experimental determination of the temperature-dependent unfolding rate constants for E. coli thioredoxin and several laboratory resurrections of Precambrian thioredoxins (Fig 1).

, 2016
Guanidine-induced denaturation experiments were performed at several temperatures and guanidine concentration for each thioredoxin variant. Values of the unfolding rate constants (kU) were derived from the fits of exponential functions to the ...
Eric A. Gaucher (358033), Beatriz Ibarra-Molero (158272), M. Luisa Romero-Romero (347004), Valeria A. Risso (205127), Sergio Martinez-Rodriguez (2814223), Jose M. Sanchez-Ruiz (118283)   +5 more
core   +1 more source

Recent advances in pancreatic β‐cell dysfunction in type 2 diabetes mellitus: Intracellular stress and dedifferentiation

Journal of Diabetes Investigation, EarlyView.
Nozomi Kido, Shun‐ichiro Asahara
wiley   +1 more source

Ro5‐4864, a ligand of the mitochondrial translocator protein, protects against heart failure in mice via regulation of the p62‐Keap1‐Nrf2 axis

The Journal of Physiology, EarlyView.
Abstract figure legend Graphical abstract of the proposed Ro5‐4864 mechanism of action via p62‐Keap1‐Nrf2 axis in heart failure. TSPO, the 18‐kDa mitochondrial translocator protein of the outer mitochondrial membrane, can directly interact with p62 (also known as SQSTM1), which is crucial for the degradation of damaged mitochondria by autophagy ...
Daphne A. Diloretto, Phung N. Thai, Gabriela Grigorean, Veneese J. Brown, Tjien Dwyer, Nipavan Chiamvimonvat, Elena N. Dedkova, Saul Schaefer   +7 more
wiley   +1 more source

NTRC and thioredoxins m1/m2 underpin the light acclimation of plants on proteome and metabolome levels

During photosynthesis, plants must manage strong fluctuations in light availability on different time scales, leading to long-term acclimation and short-term responses. However, little is known about the regulation and coordination of these processes and
Graf, A., Fernie, A., Geigenberger, P., Armbruster, U., Marino, G., Siemiatkowska, B., Arrivault, S., Dziubek, D., Poeker, L., Alseekh, S.   +9 more
core   +1 more source

The hydrogen peroxide-sensitive proteome of the chloroplast in vitro and in vivo

, 2013
Muthuramalingam M, Matros A, Scheibe R, Mock H-P, Dietz K-J. The hydrogen peroxide-sensitive proteome of the chloroplast in vitro and in vivo. Frontiers in Plant Science.
Hans-Peter eMock, Hans-Peter Mock, Renate eScheibe, Scheibe, Renate, Meenakumari eMuthuramalingam, Meenakumari Muthuramalingam, Karl-Josef Dietz, Matros, Andrea, Karl-Josef eDietz, Andrea Matros, Dietz, Karl-Josef, Mock, Hans-Peter, Renate Scheibe, Muthuramalingam, Meenakumari, Andrea eMatros   +14 more
core   +1 more source

Antioxidant supplementation blunts the proteome response to 3 weeks of sprint interval training preferentially in human type 2 muscle fibres

The Journal of Physiology, EarlyView.
Abstract figure legend Sprint interval training (SIT) is a popular time‐efficient type of endurance training. Healthy young men performed nine SIT sessions (4–6 × 30 s all‐out cycling sprints) over 3 weeks while being supplemented with antioxidants (high doses of vitamins C and E) or placebo. Muscle biopsies taken before and after the first SIT session
Victoria L. Wyckelsma, Marta Murgia, Sigitas Kamandulis, Stefano Gastaldello, Marius Brazaitis, Audrius Snieckus, Nerijus Eimantas, Mati Pääsuke, Sebastian Edman, William Apro, Daniel C. Andersson, Håkan Westerblad, Tomas Venckunas   +12 more
wiley   +1 more source

Yeast thioredoxin genes

Journal of Biological Chemistry, 1991
Based on the conserved protein sequence of thioredoxins from yeast and other organisms, two primers were synthesized for polymerase chain reaction of yeast genomic DNA. A 34-base pair (bp) sequence around the active site of yeast thioredoxin was obtained from the polymerase chain reaction product.
openaire   +2 more sources

Supplementary information with figures from Ancient thioredoxins evolved to modern-day stability–function requirement by altering native state ensemble

, 2018
Thioredoxins (Thrxs)—small globular proteins that reduce other proteins—are ubiquitous in all forms of life, from archaea to mammals. Although ancestral thioredoxins share sequential and structural similarity with the modern-day (extant) homologues, they
Sefika Banu Ozkan (5030156), Kingshuk Ghosh (659701), Tushar Modi (5030159), Jonathan Huihui (4477384)   +3 more
core   +1 more source