Results 131 to 140 of about 6,985 (261)

Transcriptional Regulation of HSP60, HSP70, and HSP90 in Response to Selenium Nanoparticles and Sodium Selenite in Periparturient Cloned Saanen Goats and Their Offspring

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
Selenium nanoparticles (SeNPs) outperform sodium selenite in raising serum selenium levels and suppressing HSP60, HSP70, and HSP90 transcription in periparturient goats and their offspring, indicating reduced cellular stress regardless of cloning status.
Gholam‐Ali Kojouri, Hossein Hassanpour, Ahmad Yousefi   +2 more
wiley   +1 more source

A universal cis-proline lock defines catalysis in thioredoxin-fold enzymes. [PDF]

Commun Biol
Cunliffe T, Wang G, Penning S, Subedi P, Totsika M, Paxman JJ, Heras B.   +6 more
europepmc   +1 more source

PCK2 Inhibition Reverses Cisplatin Resistance of Non‐Small Cell Lung Cancer by Triggering Ferroptosis

The FASEB Journal, Volume 40, Issue 16, 31 August 2026.
Metabolic enzyme PCK2 is aberrantly upregulated in cisplatin‐resistant NSCLC cells, which inhibits ferroptosis and ultimately facilitates tumor chemoresistance. The small‐molecule inhibitor RGB‐286638 directly binds to the key R454 functional site of PCK2 protein, efficiently inhibits PCK2 expression, and rescues PCK2‐mediated ferroptosis suppression ...
Jing Liu, Ziyan Wang, Chen Gu, Yili Chen, Yang Yang, Jianjie Zhu, Yihua Zhang, Yuna Shao, Xiaodong Pang, Yujie Ge, Huiwen Qian, Jian‐an Huang, Zeyi Liu, Yuanyuan Zeng, Cheng Ji   +14 more
wiley   +1 more source

Redox signals as a language of interorganellar communication in plant cells

Open Life Sciences, 2013
Kopczewski Tomasz, Kuźniak Elżbieta
doaj   +1 more source

Mutations in the Txnip PPXY motifs protect against myocardial infarction despite enhanced protein stability. [PDF]

Am J Physiol Heart Circ Physiol
Nakayama Y, Kitaura A, Abdali SA, Nguyen TD, Yoshioka J.   +4 more
europepmc   +1 more source

Proline‐Derived N‐Heterocyclic Carbene Gold(I) Complexes With Dual DNA Binding and Thioredoxin Reductase Inhibition

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
Proline‐derived Au(I)–NHC complexes display potent anticancer activity against lung and triple‐negative breast cancer cells. The cationic complexes promote DNA intercalation, thioredoxin reductase inhibition, ROS overproduction, and mitochondrial membrane depolarization, ultimately triggering apoptotic cell death through a multimodal mechanism of ...
Giacomo Cassarà, María Gil‐Moles, Thomas Scattolin, M. Concepción Gimeno   +3 more
wiley   +1 more source

Thioredoxin [PDF]

, 2020
openaire   +2 more sources

Role of thioredoxin reductase (TrxB) in oxidative stress response of <i>Francisella tularensis</i> live vaccine strain. [PDF]

J Bacteriol
Higgs M, Ma Z, Centone A, Bakshi CS, Malik M.   +4 more
europepmc   +1 more source

Nucleoredoxin 1 in Wheat: Genomic Analysis and Demonstration of Its Role in Redox Homeostasis and Stress Resilience. [PDF]

Plant Direct
Ghafoor MS, Naz R, Hussain A, Nosheen A, Yasmin H, Sajjad M, Shier WT, Keyani R.   +7 more
europepmc   +1 more source

Functional relationship of atypical thioredoxins with NADPH-thioredoxin reductase C and 2-Cys peroxiredoxins in Arabidopsis chloroplasts. [PDF]

J Exp Bot
Jiménez-López J, Casatejada A, Gálvez-Ramírez A, Pérez-Ruiz JM, Cejudo FJ.   +4 more
europepmc   +1 more source