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Fish Peroxiredoxins and Their Role in Immunity [PDF]

open access: yesBiology, 2015
Peroxiredoxins (Prxs) are a family of antioxidant enzymes that protect cells from oxidative damage. In addition, Prxs may act as modulators of inflammation, protect against cell death and tumour progression, and facilitate tissue repair after damage. The
Alberto Cuesta   +2 more
exaly   +7 more sources

Peroxiredoxin, Senescence, and Cancer

open access: yesCells, 2022
Peroxiredoxins are multifunctional enzymes that play a key role in protecting cells from stresses and maintaining the homeostasis of many cellular processes.
Mengyao Wu   +5 more
doaj   +3 more sources

Oxidative stress in Prymnesium parvum: cellular mechanisms, redox regulation, and implications for harmful algal bloom management [PDF]

open access: yesFrontiers in Plant Science
Prymnesium parvum is a mixotrophic haptophyte known for its harmful algal blooms (HABs), which are driven by its ability to adapt to fluctuating environmental conditions, particularly osmotic and oxidative stress.
Tomasz Krupnik
doaj   +2 more sources

The Role of Peroxiredoxins in the Regulation of Sepsis

open access: yesAntioxidants, 2022
Oxidative stress, a result of a disturbance in redox homeostasis, is considered to be one of the main aggravating events in the pathogenesis of immune disorders.
Kana Unuma   +2 more
exaly   +3 more sources

Insect Peroxiredoxins: A Comprehensive Review of Their Classification, Distribution, Structural Features, Expression Profiles and Physiological Functions [PDF]

open access: yesInsects
With the development of technology, an increasing amount of literature regarding the expression profiles and physiological functions of Prxs has been published. Despite this growing interest, there is currently no systematic review of expression profiles
Li Yang   +4 more
doaj   +2 more sources

Characterization of the Biochemical Recurrence Prediction Ability and Progression Correlation of Peroxiredoxins Family in Prostate Cancer Based on Integrating Single‐Cell RNA‐Seq and Bulk RNA‐Seq Cohorts [PDF]

open access: yesCancer Medicine
Introduction The peroxiredoxins (PRDXs) family plays a crucial role in balancing reactive oxygen species (ROS) levels in tumor cells. However, its potential role in prognosis and therapy response of prostate cancer (PCa) remains unknown.
Shan Tang   +15 more
doaj   +2 more sources

Review of Postmortem Protein Oxidation in Skeletal Muscle and the Role of the Peroxiredoxin Family of Endogenous Antioxidants

open access: yesMeat and Muscle Biology, 2023
The development of fresh meat quality is dictated by biochemical changes during the perimortem and postmortem period. Lipid and protein oxidation in postmortem skeletal muscle and meat products is detrimental to product quality.
Brian M Patterson   +3 more
doaj   +2 more sources

Pitfalls of Mitochondrial Redox Signaling Research

open access: yesAntioxidants, 2023
Redox signaling from mitochondria (mt) to the cytosol and plasma membrane (PM) has been scarcely reported, such as in the case of hypoxic cell adaptation or (2-oxo-) 2-keto-isocaproate (KIC) β-like-oxidation stimulating insulin secretion in pancreatic β ...
Petr Ježek
doaj   +1 more source

The Human 2-Cys Peroxiredoxins form Widespread, Cysteine-Dependent- and Isoform-Specific Protein-Protein Interactions

open access: yesAntioxidants, 2021
Redox signaling is controlled by the reversible oxidation of cysteine thiols, a post-translational modification triggered by H2O2 acting as a second messenger.
Loes van Dam   +6 more
doaj   +1 more source

PRDX1 Influences The Occurrence and Progression of Liver Cancer by Inhibiting Mitochondrial Apoptosis Pathway [PDF]

open access: yesCell Journal, 2022
ObjectiveThe aim of this study is to elucidate the role of PRDX1 in hepatocellular carcinoma using hepatomacells.Materials and MethodsIn this experimental study, we elucidated role of PRDX1, using hepatoma cell lines.ResultsPRDX1 was upregulated in ...
Hong-hua Sun   +4 more
doaj   +1 more source

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