Results 11 to 20 of about 6,985 (261)
Physiological functions of thioredoxin and thioredoxin reductase [PDF]
European Journal of Biochemistry, 2000 Thioredoxin, thioredoxin reductase and NADPH, the thioredoxin system, is ubiquitous from Archea to man. Thioredoxins, with a dithiol/disulfide active site (CGPC) are the major cellular protein disulfide reductases; they therefore also serve as electron donors for enzymes such as ribonucleotide reductases, thioredoxin peroxidases (peroxiredoxins) and ...
E S, Arnér, A, Holmgren
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Biochemical Journal, 2000 The mammalian thioredoxin reductases (TrxRs) are a family of selenium-containing pyridine nucleotide-disulphide oxidoreductases with mechanistic and sequence identity, including a conserved -Cys-Val-Asn-Val-Gly-Cys- redox catalytic site, to glutathione reductases.
D, Mustacich, G, Powis
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Redox Regulation by Thioredoxin and Thioredoxin‐Binding Proteins [PDF]
IUBMB Life, 2001 AbstractRecent works have shown the importance of reduction/oxidation (redox) regulation in various biological phenomena. Thioredoxin is a 12‐kDa protein with redox‐active dithiol in the active site ‐Cys‐Gly‐Pro‐Cys‐ and constitutes a major thiol reducing system, the thioredoxin system.
A, Nishiyama +4 more
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Thioredoxin and thioredoxin binding protein 2 in the liver [PDF]
IUBMB Life, 2008 AbstractThioredoxin (TRX) is a 12‐kDa protein with redox‐active dithiol in the active site ‐Cys‐Gly‐Pro‐Cys‐ and constitutes a major thiol reducing system. TRX protects cells from stress‐induced damage through antioxidative, antiapoptotic, and anti‐inflammatory effect.
Hiroaki, Okuyama +5 more
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Regulatory redox state in tree seeds
Acta Societatis Botanicorum Poloniae, 2017 Peroxiredoxins (Prx) are important regulators of the redox status of tree seeds during maturation and long-term storage. Thioredoxins (Trx) are redox transmitters and thereby regulate Prx activity.
Ewelina Ratajczak, Karl Josef Dietz
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NTRC Effects on Non-Photochemical Quenching Depends on PGR5
Antioxidants, 2021 Non-photochemical quenching (NPQ) protects plants from the detrimental effects of excess light. NPQ is rapidly induced by the trans-thylakoid proton gradient during photosynthesis, which in turn requires PGR5/PGRL1-dependent cyclic electron flow (CEF ...
Belen Naranjo +3 more
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Crystal structure of the human thioredoxin reductase–thioredoxin complex [PDF]
Nature Communications, 2011 Thioredoxin reductase 1 (TrxR1) is a homodimeric flavoprotein crucially involved in the regulation of cellular redox homeostasis, growth, and differentiation. Its importance in various diseases makes TrxR1 a highly interesting drug target. Here we present the first crystal structures of human TrxR1 in complex with its substrate thioredoxin (Trx).
Fritz-Wolf, K. +4 more
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Frontiers in Cellular and Infection Microbiology, 2017 Microbes employ the thioredoxin system to defend against oxidative stress and ensure correct disulfide bonding to maintain protein function. Listeria monocytogenes has been shown to encode a putative thioredoxin, TrxA, but its biological roles and ...
Changyong Cheng +15 more
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Using Resurrected Ancestral Proviral Proteins to Engineer Virus Resistance
Cell Reports, 2017 Proviral factors are host proteins hijacked by viruses for processes essential for virus propagation such as cellular entry and replication. Pathogens and their hosts co-evolve. It follows that replacing a proviral factor with a functional ancestral form
Asunción Delgado +3 more
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In silico analysis of Eucalyptus thioredoxins
Genetics and Molecular Biology, 2005 The Eucalyptus Genome Sequencing Project (FORESTs), an initiative from the Brazilian ONSA consortium (Organization for Nucleotide Sequencing and Analysis), has achieved the sequencing of 123.889 EST clones from 18 different cDNA libraries.
Aulus Estevão Barbosa, Paulo Marinho
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