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Rhodanese as a thioredoxin oxidase

The International Journal of Biochemistry & Cell Biology, 2000
A major catalytic difference between the two most common isoforms of bovine liver mitochondrial rhodanese (thiosulfate: cyanide sulfurtransferase, EC 2.8.1.1) has been observed. Both isoforms were shown to be capable of using reduced thioredoxin as a sulfur-acceptor substrate.
D L, Nandi, P M, Horowitz, J, Westley
openaire   +2 more sources

The thioredoxin system in cancer

Seminars in Cancer Biology, 2006
Thioredoxin (Trx), NADPH and thioredoxin reductase (TrxR) comprise a thioredoxin system which exists in nearly all living cells. It functions in thiol-dependent thiol-disulfide exchange reactions crucial to control of the reduced intracellular redox environment, cellular growth, defense against oxidative stress or control of apoptosis and has multi ...
Elias S J, Arnér, Arne, Holmgren
openaire   +2 more sources

Insights into the Specificity of Thioredoxin Reductase−Thioredoxin Interactions. A Structural and Functional Investigation of the Yeast Thioredoxin System

Biochemistry, 2010
The enzymatic activity of thioredoxin reductase enzymes is endowed by at least two redox centers: a flavin and a dithiol/disulfide CXXC motif. The interaction between thioredoxin reductase and thioredoxin is generally species-specific, but the molecular aspects related to this phenomenon remain elusive.
Oliveira, Marcos A.   +5 more
openaire   +3 more sources

Crystal Structure of the Plasmodium falciparum Thioredoxin Reductase–Thioredoxin Complex

Journal of Molecular Biology, 2013
Over the last decades, malaria parasites have been rapidly developing resistance against antimalarial drugs, which underlines the need for novel drug targets. Thioredoxin reductase (TrxR) is crucially involved in redox homeostasis and essential for Plasmodium falciparum. Here, we report the first crystal structure of P.
Fritz-Wolf, K.   +6 more
openaire   +3 more sources

Thioredoxin

Annual Review of Biochemistry, 1985
openaire   +2 more sources

Thioredoxins m regulate plastid glucose-6-phosphate dehydrogenase activity in Arabidopsis roots under salt stress

Frontiers in Plant Science, 2023
Amna Mhamdi   +2 more
exaly  

[Thioredoxin].

Nihon rinsho. Japanese journal of clinical medicine, 2005
Aoi, Son, Junji, Yodoi, Hajime, Nakamura
openaire   +3 more sources

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