Results 41 to 50 of about 31,059 (323)
Functional analyses of ancestral thioredoxins provide insights into their evolutionary history
Journal of Biological Chemistry, 2019 Thioredoxin (Trx) is a conserved, cytosolic reductase in all known organisms. The enzyme receives two electrons from NADPH via thioredoxin reductase (TrxR) and passes them on to multiple cellular reductases via disulfide exchange. Despite the ubiquity of
S. Napolitano +3 more
semanticscholar +1 more source
Redox Regulation of Starch Metabolism
Frontiers in Plant Science, 2018 Metabolism of starch is a major biological integrator of plant growth supporting nocturnal energy dynamics by transitory starch degradation as well as periods of dormancy, re-growth, and reproduction by utilization of storage starch.
Katsiaryna Skryhan +4 more
doaj +1 more source
Antioxidants, 2018 Thiol-based redox control is one of the important posttranslational mechanisms of the tetrapyrrole biosynthesis pathway. Many enzymes of the pathway have been shown to interact with thioredoxin (TRX) and Nicotinamide adenine dinucleotide phosphate (NADPH)
Daniel Wittmann +3 more
doaj +1 more source
Crystal structure of the human thioredoxin reductase–thioredoxin complex [PDF]
Nature Communications, 2011 Thioredoxin reductase 1 (TrxR1) is a homodimeric flavoprotein crucially involved in the regulation of cellular redox homeostasis, growth, and differentiation. Its importance in various diseases makes TrxR1 a highly interesting drug target. Here we present the first crystal structures of human TrxR1 in complex with its substrate thioredoxin (Trx).
Fritz-Wolf, K. +4 more
openaire +3 more sources
Chloride intracellular channel 3: a secreted pro-invasive oxidoreductase [PDF]
, 2017 No abstract ...
Norman, Jim, Zanivan, Sara
core +1 more source
Sperm DNA fragmentation, recurrent implantation failure and recurrent miscarriage
Asian Journal of Andrology, 2015 Evidence is increasing that the integrity of sperm DNA may also be related to implantation failure and recurrent miscarriage (RM). To investigate this, the sperm DNA fragmentation in partners of 35 women with recurrent implantation failure (RIF ...
Carol Coughlan +7 more
doaj +1 more source
Advances in Redox Research, 2023 Reactive Oxygen Species (ROS) can be harmful compounds that can cause damage to macromolecules like lipids, proteins, and DNA when their levels exceed cellular defense mechanisms.
Cecilia Picazo +5 more
doaj +1 more source
Eucalyptus grandis THIOREDOXINS, DIVERSITY AND GENE EXPRESSION [PDF]
Revista Árvore, 2020 Tree genomes have been sequenced in recent years providing a source of basic information on multigenic family characterization. Comparative genomics based on those complete genome sequences available in public database is an important tool providing ...
Vitória Régia Alves Cavalcante +3 more
doaj +2 more sources
PLANT THIOREDOXIN SYSTEMS REVISITED [PDF]
Annual Review of Plant Physiology and Plant Molecular Biology, 2000 ▪ Abstract Thioredoxins, the ubiquitous small proteins with a redox active disulfide bridge, are important regulatory elements in plant metabolism. Initially recognized as regulatory proteins in the reversible light activation of key photosynthetic enzymes, they have subsequently been found in the cytoplasm and in mitochondria.
Schürmann, Peter, Jacquot, J.-P.
openaire +2 more sources
Human sperm chromatin epigenetic potential: genomics, proteomics, and male infertility
Asian Journal of Andrology, 2015 The classical idea about the function of the mammalian sperm chromatin is that it serves to transmit a highly protected and transcriptionally inactive paternal genome, largely condensed by protamines, to the next generation.
Judit Castillo +3 more
doaj +1 more source