Results 81 to 90 of about 2,711 (217)

Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release. [PDF]

, 2016
Human genetic studies show that the voltage gated sodium channel 1.7 (Nav1.7) is a key molecular determinant of pain sensation. However, defining the Nav1.7 contribution to nociceptive signalling has been hampered by a lack of selective inhibitors.
Alexandrou, AJ, Brown, AR, Butt, RP, Castle, NA, Chapman, ML, Cox, PJ, Dib-Hajj, SD, Doyle, R, Estacion, M, Gutteridge, A, Hounshell, JA, Krafte, D, Lin, Z, Marron, BE, Mis, MA, Patel, MK, Payne, EC, Printzenhoff, D, Randall, A, Rivara, M, Stevens, EB, Storer, RI, Stupple, PA, Swain, NA, Turner, J, Waxman, SG, West, C, Wilbrey, A   +27 more
core   +1 more source

Comparison of the cardiovascular and neural activity of endothelin‐1, −2, −3 and respective proendothelins: effects of phosphoramidon and thiorphan [PDF]

, 1993
Giovan Giuseppe Mattera, Anthony Eglezos, Anna Rita Renzetti, Jacques Mizrahi   +3 more
openalex   +1 more source

Neprilysin deficiency reduces hepatic gluconeogenesis in high fat-fed mice. [PDF]

Peptides, 2023
Esser N, Mongovin SM, Mundinger TO, Barrow BM, Zraika S.   +4 more
europepmc   +1 more source

The Effects of One-Point Mutation on the New Delhi Metallo Beta-Lactamase-1 Resistance toward Carbapenem Antibiotics and β-Lactamase Inhibitors: An In Silico Systematic Approach. [PDF]

Int J Mol Sci, 2022
Tran VT, Tran VH, Nguyen DN, Do TG, Vo TP, Nguyen TT, Huynh PNH, Thai KM.   +7 more
europepmc   +1 more source

Thiorphan enhances bradykinin-induced vascular relaxation in hypoxic/hyperkalaemic porcine coronary artery [PDF]

, 2003
Irén Krassói, János Pataricza, Julius Gy. Papp   +2 more
openalex   +1 more source

Inhibition of kinin metabolism and the role of the vascular B₁ kinin receptor in patients with congestive heart failure [PDF]

, 2008
BACKGROUND Angiotensin-converting enzyme and neutral endopeptidase are endothelial metallopeptidases that metabolise bradykinin. Inhibitors of angiotensinconverting enzyme improve symptoms and survival in patients with heart failure and vascular ...
Cruden, Nicholas Le May
core   +1 more source

Processing and clearance of atrial natriuretic factor [PDF]

, 1991
Gerbes, Alexander L., Henriksen, Jens H., Vollmar, Angelika M.   +2 more
core   +1 more source

Degradation and clearance of atrial natriuretic factors [PDF]

, 1990
Adnot, Almeida, Anand-Srivastava, Anand-Srivastava, Anderson, Ando, Arendt, Arendt, Ballermann, Ballermann, Bates, Bertrand, Bianchi, Bianchi, Cachofeiro, Cantin, Cantin, Chartier, Chinkers, Cody, Crozier, De Bold, De Lean, Drexler, Espiner, Fethiere, Fulcher, Gerbes, Gerbes, Gerbes, Gines, Gros, Gutkowska, Hasegawa, Henriksen, Hinko, Hollister, Inagami, Kenny, Koehn, Koepke, Kollenda, Koseki, Krieter, Kurosawa, Lafferty, Laffi, Lang, Lang, Laragh, Leitman, Lieorens, Luft, Maack, Mantyh, Marumo, Masuda, Matsas, Matsas, Matsas, Misono, Murthy, Nakao, Needleman, Northridge, Olins, Olins, Olins, Pandey, Porter, Predel, Raine, Richards, Riegger, Saito, Scarborough, Schafferhans, Schiebinger, Schutten, Schwartz, Seymour, Shima, Sonnenberg, Stephenson, Stewart, Sudhir, Sugiyama, Sybertz, Sybertz, Takayanagi, Tamburini, Tang, Thibault, Trapani, Trapani, Trippodo, Vierhapper, Vollmar, Vollmar, Vollmar, Webb, Woods, Yukimura   +102 more
core   +1 more source

Modulation of endothelin production and metabolism in guinea pig cultured tracheal epithelial cells [PDF]

, 1997
Endothelins (ET-1, ET-2, ET-3) are potent bronchoconstrictors and growth-promoting mediators. ET-1 is released from various cells such as endothelial and epithelial cells.
Yang, Quan
core   +1 more source

Characterization of the Vasoactivity of Tachykinins in Isolated Rat Kidney: Functional Studies and in Vitro Receptor Autoradiography [PDF]

, 1994
Although tachykinins have potent vascular actions, their effect on renal resistance blood vessels is currently unknown. The vasoactive properties of tachykinins and related analogs were assessed in isolated perfused rat kidney. At a basal
Chen, Yuejin
core   +1 more source