Results 71 to 80 of about 1,394 (176)
Copyright © 2007 by Institute of Pharmacology Polish Academy of Sciences
Inhibition of neutral endopeptidase by thiorphan does not modify coronary vascular responses to angiotensin I, angiotensin II and bradykinin in the isolated guinea pig ...
Magdalena Lomnicka +3 more
core
Atrial natriuretic factor inhibits ciliary motility in cultured rabbit tracheal epithelium
To study the effect of atrial natriuretic factor (ANF) on airway ciliary motility, we measured ciliary beat frequency by a photoelectric method in response to ANF in cultured tracheal epithelial cells from rabbits. Addition of ANF but not [Tyr8]ANF-(5-27)
S. Horii +9 more
core +1 more source
Interaction of ANP and bradykinin during endopeptidase 24.11 inhibition: renal effects
Experiments were performed on anesthetized rats to determine whether inhibition of endopeptidase 24.11 (EP) potentiates the biological activity of atrial natriuretic peptide, ANP-(99-126), and to examine the mechanisms that underlie this effect ...
A. J. Trapani, D. E. McGraw, G. J. Smits
core +1 more source
or the past few decades membrane zinc metallopeptidases have been identified as important therapeutic targets in the control of pain. In particular, neutral endopeptidase (NEP) has been shown to play critical roles in the metabolism of the endogenous ...
Matteo Zanda +13 more
core +1 more source
Neuroprotective effect of G-CSF depends on NEP.
A–F, Fluorescent microscopic images of mouse primary cortical neuron cultures. A, Untreated neurons. B, Neurons treated with 5 µM oAβ1–42. C, Neurons treated with 5 µM oAβ1–42 and 100 ng/ml G-CSF. D, Neurons treated with 5 µM oAβ1–42, 100 ng/ml G-CSF and
Yukiko Doi (217308) +10 more
core +1 more source
The design of 1,3-dacylaminopropan-2-ols as CNS-directed carrier groups is based on their resemblance to endogenous lipids and the properties of pseudotriglyceride esters to facilitate the brain penetration of therapeutic agents.
Mergen, F. +4 more
core +1 more source
Neprilysin deficiency reduces hepatic gluconeogenesis in high fat-fed mice. [PDF]
Esser N +4 more
europepmc +1 more source
Evidence for non-adrenergic non-cholinergic contractile responses in bovine and swine trachea
Non-adrenergic non-cholinergic (NANC) contraction of airway smooth muscle has been observed in some but not all animal species. The aim of this study was to investigate the NANC-contractile responses in bovine and swine trachea.
AMORENA, Michele +6 more
core +1 more source
The angiotensin coverting enzyme (ACE) inhibitor [3H]SQ29,852 identified a single high affinity recognition site (defined by 10.0 μM captopril) in the human temporal cortex (pKD 8.62 ± 0.03; Bmax 248 ± 24 fmol mg-1 protein, mean±S.E.M., n = 4).
Costall, B. +6 more
core +1 more source
The Effects of One-Point Mutation on the New Delhi Metallo Beta-Lactamase-1 Resistance toward Carbapenem Antibiotics and β-Lactamase Inhibitors: An In Silico Systematic Approach. [PDF]
Tran VT +7 more
europepmc +1 more source

