Results 71 to 80 of about 1,836 (178)

Neprilysin is a mediator of alternative renin-angiotensin-system activation in the murine and human kidney [PDF]

, 2016
Cardiovascular and renal pathologies are frequently associated with an activated renin-angiotensin-system (RAS) and increased levels of its main effector and vasoconstrictor hormone angiotensin II (Ang II). Angiotensin-converting-enzyme-2 (ACE2) has been
Antlanger, M., Bader, M., Domenig, O., Elased, K.M., Grobe, N., Gurley, S.B., Kaltenecker, C.C., Kovarik, J.J., Königshausen, E., Linker, R.A., Manzel, A., Motta-Santos, D., Poglitsch, M., Santos, R.A., Stegbauer, J., Säemann, M.D., van Oyen, D.   +16 more
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Emerging roles of pathogens in Alzheimer disease [PDF]

, 2017
Chronic spirochetal infection can cause slowly progressive dementia, cortical atrophy and amyloid deposition in the atrophic form of general paresis.
Miklossy, Judith
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Acute Inhibition of Intestinal Neprilysin Enhances Insulin Secretion via GLP-1 Receptor Signaling in Male Mice. [PDF]

Endocrinology, 2023
Esser N, Mundinger TO, Barrow BM, Zraika S.   +3 more
europepmc   +1 more source

Characterisation of the pharmacological actions in humans of multiple vasoactive enzyme inhibitors with therapeutic potential in heart failure [PDF]

, 2007
Introduction The work described in this thesis looks particularly but not exclusively at two recently developed molecules which have dual enzyme inhibitor activity.
Seed, Alison
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Neprilysin deficiency reduces hepatic gluconeogenesis in high fat-fed mice. [PDF]

Peptides, 2023
Esser N, Mongovin SM, Mundinger TO, Barrow BM, Zraika S.   +4 more
europepmc   +1 more source

The Effects of One-Point Mutation on the New Delhi Metallo Beta-Lactamase-1 Resistance toward Carbapenem Antibiotics and β-Lactamase Inhibitors: An In Silico Systematic Approach. [PDF]

Int J Mol Sci, 2022
Tran VT, Tran VH, Nguyen DN, Do TG, Vo TP, Nguyen TT, Huynh PNH, Thai KM.   +7 more
europepmc   +1 more source

Modulation of endothelin production and metabolism in guinea pig cultured tracheal epithelial cells [PDF]

, 1997
Endothelins (ET-1, ET-2, ET-3) are potent bronchoconstrictors and growth-promoting mediators. ET-1 is released from various cells such as endothelial and epithelial cells.
Yang, Quan
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Biochemical and pharmacological studies of the metabolism of dynorphin 1-8 [PDF]

, 1990
The metabolism of the opioid peptide [3H]dynorphin 1-8 by slices of central nervous system (c.n.s.) and peripheral tissues, from the rat and guinea-pig has been studied.
Diane M. Dixon (7167092)
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Processing and clearance of atrial natriuretic factor [PDF]

, 1991
Gerbes, Alexander L., Henriksen, Jens H., Vollmar, Angelika M.   +2 more
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Degradation and clearance of atrial natriuretic factors [PDF]

, 1990
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