Results 81 to 90 of about 1,394 (176)
, 2007 Recently, a relationship between glyceraldehyde-3-phosphate dehydrogenase (GAPDH) and the beta-amyloid precursor protein (betaAPP) in relationship with the pathogenesis of Alzheimer's disease (AD) has been suggested.
Petya Dimitrova +8 more
core +1 more source
, 1992 A range of penicillins have been examined as competitive reversible inhibitors of enkephalinase (neutral endopeptidase; EC 3.4.24.11). Carfecillin (Ki = 0.18 microM) was the most potent inhibitor in the series, whereas cloxacillin (27.5 microM ...
Livingston, S. J. +3 more
core +1 more source
, 2008 Background and purpose: C-type natriuretic peptide (CNP) has been proposed to make a fundamental contribution in arterial endothelium-dependent hyperpolarization to acetylcholine.
Félétou, M +3 more
core +1 more source
Design and Synthesis of Substrate Analogue Inhibitors of Peptide Deformylase†
, 2016 Series of substrates derivatives of peptide deformylase were systematically synthesized and studied for their capacities to undergo hydrolysis. Data analysis indicated the requirement for a hydrophobic first side chain and for at least two main chain ...
Luc Patiny (1347723) +3 more
core +1 more source
HIV-1 Tat alters the processing of APP and increases the levels of β-CTF and Aβ42.
, 2013 (A) Level of β-CFT was increased in Lenti-Tat, or Lenti-mTat infected cells while the amount of total APP was not changed. U-87 MG cells were transduced with mock, Lenti-Tat, or Lenti-mTat virus and incubated for 14 days. The cell number was counted, and
Jiyoung Kim (149493) +2 more
core +1 more source
G-CSF enhances oAβ degradation by activation of NEP.
, 2014 A, Representative RT-PCR data for NEP in neurons. G-CSF stimulation upregulated NEP expression. NT, no treatment. B, ELISA data for NEP. NT, no treatment. Values are means ± SEM (n = 3). C, NEP enzymatic activity assay.
Yukiko Doi (217308) +10 more
core +1 more source
Attenuation of renal effects of atrial natriuretic factor during rat pregnancy
, 1995 The influence of pregnancy on renal responses to atrial natriuretic factor (ANF) was determined in urethane-anesthetized Sprague-Dawley rats. Infusions of ANF caused a significantly greater increase in urinary excretion of fluid, sodium, and potassium ...
S. Mulay +3 more
core +1 more source
Opioid Withdrawal Abruptly Disrupts Amygdala Circuit Function by Reducing Peptide Actions. [PDF]
J Neurosci, 2023 Gregoriou GC +4 more
europepmc +1 more source
, 1995 Cette étude porte sur la caractérisation des enzymes responsables de la conversion des précurseurs des endothélines, les "big" endothélines-1, 2 et 3, en leurs métabolites actifs au niveau du parenchyme pulmonaire et des bronches supérieures de
Lebel, Nathalie
core
Aβ/Amyloid Precursor Protein-Induced Hyperexcitability and Dysregulation of Homeostatic Synaptic Plasticity in Neuron Models of Alzheimer's Disease. [PDF]
Front Aging Neurosci, 2022 Martinsson I +11 more
europepmc +1 more source