The inactivation of enkephalins by brain tissue [PDF]
, 1985 Imperial Users ...
Pritchard, K., Pritchard, K.
core
Inhibition of kinin metabolism and the role of the vascular B₁ kinin receptor in patients with congestive heart failure [PDF]
, 2008 BACKGROUND Angiotensin-converting enzyme and neutral endopeptidase are endothelial metallopeptidases that metabolise bradykinin. Inhibitors of angiotensinconverting enzyme improve symptoms and survival in patients with heart failure and vascular ...
Cruden, Nicholas Le May
core +1 more source
Characterization of the Vasoactivity of Tachykinins in Isolated Rat Kidney: Functional Studies and in Vitro Receptor Autoradiography [PDF]
, 1994 Although tachykinins have potent vascular actions, their effect on renal resistance blood vessels is currently unknown. The vasoactive properties of tachykinins and related analogs were assessed in isolated perfused rat kidney. At a basal
Chen, Yuejin
core +1 more source
Prodrugs targeting the central nervous system (cns) [PDF]
, 2015 The classical approach for delivery of drugs into the central nervous system (CNS) is associated with adverse effects and it has many limitations. Therefore, extensive efforts have been done in searching and developing novel methods for achieving such
Karaman, Donia +2 more
core
Aβ/Amyloid Precursor Protein-Induced Hyperexcitability and Dysregulation of Homeostatic Synaptic Plasticity in Neuron Models of Alzheimer's Disease. [PDF]
Front Aging Neurosci, 2022 Martinsson I +11 more
europepmc +1 more source
The Effect of Pre- & Post-Training Administration of Naloxone upon Acquisition Learning & Memory Retention during an Active Avoidance Response [PDF]
, 1984 Thirty-two male and female Balb-C mice were randomly divided into four groups of eight subjects each. The mice were injected with saline or naloxone either before or after the initial training of an active avoidance response.
Yovichin, Debra
core +1 more source
Conformational Studies on Some Inhibitors of Thermolysin and EC 3.4.24.11 [PDF]
, 1987 Molecular modeling is an exciting new approach in the field of drug design. A molecule's activity as a drug is dependent upon its conformation i.e. the three dimensional arrangement of its functional groups.
Forrest, Fiona Ruth Ferguson
core
Prediction of Phytochemicals for Their Potential to Inhibit New Delhi Metallo β-Lactamase (NDM-1). [PDF]
Pharmaceuticals (Basel), 2023 Bibi Z +10 more
europepmc +1 more source
Expression of neutral endopeptidase activity during clinical and experimental acute lung injury [PDF]
Fumimasa Amaya +4 more
core +1 more source
Distinct Inhibition Modes of New Delhi Metallo-β-lactamase-1 Revealed by NMR Spectroscopy. [PDF]
JACS Au, 2023 Cheng K +6 more
europepmc +1 more source