Results 61 to 70 of about 1,034 (134)

GPR35 agonists inhibit TRPA1-mediated colonic nociception through suppression of substance P release. [PDF]

Pain
Gupta RA, Higham JP, Pearce A, Urriola-Muñoz P, Barker KH, Paine L, Ghooraroo J, Raine T, Hockley JRF, Rahman T, St John Smith E, Brown AJH, Ladds G, Suzuki R, Bulmer DC.   +14 more
europepmc   +1 more source

Potential renoprotective effects and possible underlying mechanisms of angiotensin receptor-neprilysin inhibitors in cardiorenal syndrome. [PDF]

Front Med (Lausanne)
Rahman MM, Rahman A, Nishiyama A.
europepmc   +1 more source

GPR35 inhibits TRPA1-mediated colonic afferent hypersensitivity through suppression of Substance P release

, 2023
Gupta RA, Higham JP, Urriola-Muñoz P, Barker KH, Paine L, Ghooraroo J, Hockley JR, Rahman T, Smith ESJ, Brown AJ, Suzuki R, Bulmer DC.   +11 more
europepmc   +1 more source

Drug similarity and structure-based screening of medicinal compounds to target macrodomain-I from SARS-CoV-2 to rescue the host immune system: a molecular dynamics study. [PDF]

J Biomol Struct Dyn, 2022
Babar Z, Khan M, Zahra M, Anwar M, Noor K, Hashmi HF, Suleman M, Waseem M, Shah A, Ali S, Ali SS.   +10 more
europepmc   +1 more source

Repurposing insights: experimental and pharmacological approach on L-captopril and dimercaprol as metallo-β-lactamase inhibitors. [PDF]

FEMS Microbiol Lett
Rodríguez-Avial I, Torres S, Puglla Y, Pérez-Martín L, Sebastianes JL, Delgado-Iribarren A, Culebras E, Valderrama MJ.   +7 more
europepmc   +1 more source

Somatostatin-evoked Aβ catabolism in the brain: Mechanistic involvement of α-endosulfine-K_ATP channel pathway. [PDF]

Mol Psychiatry, 2022
Watamura N, Kakiya N, Nilsson P, Tsubuki S, Kamano N, Takahashi M, Hashimoto S, Sasaguri H, Saito T, Saido TC.   +9 more
europepmc   +1 more source

Sustainable Joullié-Ugi and Continuous Flow Implementation Led to Novel Captopril-Inspired Broad-Spectrum Metallo-β-Lactamase Inhibitors. [PDF]

J Med Chem
Alfano AI, Pelliccia S, Barone S, Cutarella L, Cancade SMI, Baia V, Cassese E, Russomanno P, Messano N, Frank D, Weizel L, Rotter MJ, Brunst S, Wichelhaus TA, Proschak E, Tedesco D, Mori M, Docquier JD, Summa V, Brindisi M.   +19 more
europepmc   +1 more source

Comprehensive review on neprilysin (NEP) inhibitors: design, structure-activity relationships, and clinical applications. [PDF]

Front Pharmacol
Zhang X, Hu C, Tian E, Shen Y, Liu W, Li J.   +5 more
europepmc   +1 more source

Enzymatic Hydrolysis of Porcine Blood as a Strategy to Obtain a Peptide-Rich Functional Ingredient. [PDF]

Int J Mol Sci
Moreno-Mariscal C, Moroni F, Pérez-Sánchez J, Mora L, Toldrá F.   +4 more
europepmc   +1 more source

An integrated biophysical approach to discovering mechanisms of NDM-1 inhibition for several thiol-containing drugs. [PDF]

J Biol Inorg Chem, 2020
Fullington S, Cheng Z, Thomas C, Miller C, Yang K, Ju LC, Bergstrom A, Shurina BA, Bretz SL, Page RC, Tierney DL, Crowder MW.   +11 more
europepmc   +1 more source