Results 1 to 10 of about 832 (140)

Green Synthesis and Characterization of Rosa roxburghii Tratt.-Mediated Gold Nanoparticles for Visual Colorimetric Assay of Tiopronin [PDF]

Nanomaterials
This study used Rosa roxburghii Tratt. crude extract (RR) as a reducing, stabilizing, and modifying agent for the green synthesis of gold nanoparticles (RR-AuNPs) via the one-pot method for the first time and established a novel colorimetric sensor for ...
Dan Liu, Shilan Feng
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Targeted activation on Bnip3 enhances mitophagy to prevent the progression of osteoarthritis [PDF]

Journal of Orthopaedic Translation
Background: The production of reactive oxygen species (ROS) and mitochondrial dysfunction in chondrocytes are closely related to cartilage degeneration in the procedure of osteoarthritis (OA).
Yong Gou, Chenggui Wang, Kejian Fu, Shenkai Su, Hangjin Zhou, Chunkai Bao, Hui Nan, Xiang Zhang, Yiyuan Xu, Qi Chen, Xinchen Gu, Baiting Chen, Lin Zheng, Chenglong Xie, Man Zhang, Enxing Xue, Jiawei Li   +16 more
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Green UHPLC approach for the quantitative determination of tiopronin residues in cleaning validation processes [PDF]

BMC Chemistry
This study presents the development and validation of a novel reverse-phase ultra-high-performance liquid chromatography (UHPLC) method for quantifying tiopronin residues on manufacturing equipment surfaces as part of cleaning validation.
Jagdish Gohel, Ajay Patel, Rajendra Kotadiya   +2 more
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Outcomes of Tiopronin and D-Penicillamine Therapy in Pediatric Cystinuria: A Clinical Comparison of Two Cases [PDF]

Reports
Background and Clinical Significance: Cystinuria is the most common genetic cause of pediatric nephrolithiasis, characterized by impaired renal cystine reabsorption and resulting in increased urinary cystine excretion.
Brooke Schaefer, Adinoyi Garba, Xiaoyan Wu   +2 more
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Nephrotic Syndrome Induced by Tiopronin in a Male Patient with Cystinuria [PDF]

Balkan Journal of Medical Genetics
Cystinuria is a rare, lifelong, autosomal recessive disorder characterized by high urine cystine excretion, leading to chronic and recurrent kidney stone formation. This inherited metabolic disorder occurs due to defective cystine, lysine, ornithine, and
Karanfilovski V, Severova Stojanoska A, Ristovska V, Gjorgjievska J, Tasic V, Arsov T, Dzekova-Vidimliski P, Plaseska-Karanfilska D, Nikolov I, Gjorgjievski N   +9 more
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A rapid HPLC method to simultaneously quantify therapeutic thiols and monitor their disulfide exchange reactions with cystine [PDF]

Orphanet Journal of Rare Diseases
This study introduces a rapid and environmentally sustainable High Performance Liquid Chromatography method to simultaneously quantify free thiols and monitor their disulfide exchange kinetics with cystine.
Azhidhack Hadjipour, Gayatri Gayatri, Patrice Rioux, Oisín N. Kavanagh   +3 more
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Evaluate the value of prolonging the duration of tiopronin for injection administration in preventing hepatotoxicity [PDF]

Scientific Reports
As part of supportive therapy, prophylaxis with tiopronin for injection (TI) against common hepatotoxicity complications has often been used. However, methods to prevent hepatotoxicity have not been established. Therefore, our study was aimed to find out
Hongye Yang, Mingzhu Lin, Mengxing Liu, Huawei Gu, Dan Li, Yu Shi, Xidong Hou   +6 more
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NELL1 membranous nephropathy: clinical associations provide mechanistic clues [PDF]

Frontiers in Nephrology
Neural epidermal growth factor-like 1 (NELL1) membranous nephropathy (MN) is notable for its segmental deposit distribution, IgG1 dominant deposits, and comparatively high rate of spontaneous remission.
Nicole K. Andeen, Vanderlene L. Kung, Rupali S. Avasare   +2 more
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Spectrophotometric Determination of Tiopronin in Pharmaceutical Preparations [PDF]

مجلة جامعة النجاح للأبحاث العلوم الطبيعية, 2001
Two spectrophotometric methods are described for the determination of tiopronin in pharmaceuticals. They are based on the oxidation-reduction reaction between tiopronin and iron (III), then forming a complex between iron (II) and ferrozine or di-2 ...
Maher Abu-Eid, Nidal Zatar, Tamara Kamal, Mohammad Hannoun   +3 more
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Tiopronin and/or NSAID? A Case of Nephrotic Syndrome and Acute Interstitial Nephritis in a Young Woman with Cystinuria.

Acta Clinica Croatica, 2021
Cystinuria is an autosomal recessive disease that leads to recurrent stone formation. Tiopronin, a glycine derivative with a free thiol similar to penicillamine, prevents stone formation and facilitates their dissolution. Nephrotic-range proteinuria is
Luka Vidović, Josipa Josipović, Petar Šenjug, Danica Galešić Ljubanović   +3 more
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