Results 41 to 50 of about 832 (140)

Silibinin, a potential fasting mimetic, inhibits hepatocellular carcinoma by triggering extrinsic apoptosis

MedComm, Volume 5, Issue 1, January 2024.
This study highlights the hepatoprotective drug silibinin triggers AMPK pathway, and inhibits intracellular ATP levels and glycolysis, which served as a fasting mimetic to induce extrinsic apoptosis and inhibit HCC growth. Silibinin achieves this effect partially by activating the AMPK–DR5 pathway.
Biying Xiao, Yanyu Jiang, Shuying Yuan, Lili Cai, Tong Xu, Lijun Jia   +5 more
wiley   +1 more source

The Hepatoprotective Possessions of Specific Iranian Medicinal Plants

Journal of Food Biochemistry, Volume 2024, Issue 1, 2024.
With its historical roots, Iranian traditional medicine has played a significant role in addressing liver‐related disorders and providing alternative approaches to synthetic drugs. Liver‐related disorders, such as hepatitis, liver cirrhosis, and nonalcoholic fatty liver disease, pose significant health challenges worldwide.
Salome Dini, Shubhra Singh, Faezeh Fatemi, Rai Aamer   +3 more
wiley   +1 more source

A novel bone cement impregnated with silver–tiopronin nanoparticles: its antimicrobial, cytotoxic, and mechanical properties

International Journal of Nanomedicine, 2013
Polina Prokopovich,1,2 Ralph Leech,3 Claire J Carmalt,3 Ivan P Parkin,3 Stefano Perni41School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff, UK; 2Institute of Medical Engineering and Medical Physics, School of Engineering, Cardiff ...
Prokopovich P, Leech R, Carmalt CJ, Parkin IP, Perni S   +4 more
doaj  

Molecular mechanisms and clinical insights of benzo[a]pyrene-related lung adenocarcinoma: New discoveries in multi-scale approaches

Ecotoxicology and Environmental Safety
While the carcinogenicity of Benzo[a]pyrene (BaP) in lung adenocarcinoma (LUAD) is well-documented, the molecular mechanisms underlying BaP-driven tumorigenesis remain not fully clear.
Zhenyu Xu, Guolu Luo, Xuchen Cao, Chongbiao Huang   +3 more
doaj   +1 more source

Cystinuria: Diagnosis, Medical and Surgical Management, and Emerging Therapies. A Narrative Review

Research and Reports in Urology
Alberto Zambudio Munuera,1,2 Patricia Rodriguez Parras,1,2 Juan Antonio Galan Llopis,3 Feliciano Grases Freixedas,4 Maria del Carmen Cano Garcia,1,2 Miguel Arrabal-Martin,1,2 Miguel Angel Arrabal Polo1,21Urology Department, San Cecilio University ...
Zambudio Munuera A, Rodriguez Parras P, Galan Llopis JA, Grases Freixedas F, Cano Garcia MDC, Arrabal-Martin M, Arrabal Polo MA   +6 more
doaj  

Increased radiosensitivity of colorectal tumors with intra-tumoral injection of low dose of gold nanoparticles

International Journal of Nanomedicine, 2016
Minghan Shi,1 Benoit Paquette,1 Thititip Thippayamontri,1 Louis Gendron,2 Brigitte Guérin,1 Léon Sanche1 1Department of Nuclear Medicine and Radiobiology, Center for Research in Radiotherapy, 2Department of Pharmacology-Physiology ...
Shi M, Paquette B, Thippayamontri T, Gendron L, Guérin B, Sanche L   +5 more
doaj  

Chemical Modification of Tiopronin for Dual Management of Cystinuria and Associated Bacterial Infections. [PDF]

ACS Appl Mater Interfaces, 2023
Kumar A, Estes Bright LM, Garren MRS, Manuel J, Shome A, Handa H.   +5 more
europepmc   +1 more source

Network meta-analysis of different liver protective drugs in the treatment of drug-induced liver injury. [PDF]

Medicine (Baltimore), 2023
Li C, Yang X, Quan Y, Wu A, Wang Y.
europepmc   +1 more source

Segmental NELL-1 Membranous Nephropathy Complicating Tiopronin Therapy. [PDF]

Kidney Int Rep, 2023
Santoriello D, Ramaswamy R, Kudose S, Markowitz GS.   +3 more
europepmc   +1 more source

Rhabdomyolysis associated with <i>Ophioglossum vulgatum</i> consumption: a case series and safety implications. [PDF]

Front Pharmacol
Li X, Liao L.
europepmc   +1 more source