Results 111 to 120 of about 14,165 (252)

In Vitro and Ultrastructural Evaluation of the Cytotoxic and Antileishmanial Activities of Thiosemicarbazone Compounds Against Promastigotes and Axenic Amastigotes of Leishmania infantum

Tropical Medicine and Infectious Disease
Leishmaniasis remains a global health challenge, and the search for effective and selective therapeutic agents is crucial. This study evaluated the in vitro antileishmanial and cytotoxic activities of thiosemicarbazone compounds (LT-70, LT-73, LT-75, and
Janderson Weydson Lopes Menezes da Silva, Andréa Regina Alves da Rocha Diniz, Alberon Ribeiro de Araújo, Gabriel Gazzoni Araújo Gonçalves, Dyana Leal Veras, Marton Kaique de Andrade Cavalcante, Jana Messias Sandes, Iranildo José da Cruz Filho, Diego Santa Clara Marques, Maria do Carmo Alves de Lima, Ana Paula Sampaio Feitosa, Luiz Carlos Alves, Fábio André Brayner   +12 more
doaj   +1 more source

Trace minerals in human health: iron, zinc, copper, manganese and fluorine [PDF]

, 2019
Trace elements exist in the environment in small amounts but play an essential part in sustaining various physiological and metabolic processes occurring within living tissues, as enzymes structure and function, bone and blood maintenance, immune ...
Ferreira da Vinha, Ana, Matos, Carla, Moutinho, Carla, Silva, Carla Sousa e   +3 more
core  

A case of vaccinia necrosum (or progressive vaccinia), with severe hypogammaglobulinaemia, treated with n-methyl isatin beta-thiosemicarbazone (33T57) [PDF]

, 1963
T. H. Flewett, F. L. Ker
openalex   +1 more source

Kinetic Insights into the Antioxidant Effect of Isatin-Thiosemicarbazone in Biodiesel Blends

Antioxidants
Biodiesel has several drawbacks, such as being prone to oxidation, having reduced stability, and having limited storage time. Antioxidants compatible with biodiesel are being used to address its drawbacks.
Nalan Türköz Karakullukçu, Halit Muğlu, Hasan Yakan, Volkan Murat Yılmaz, Sarmad Marah, İkbal Agah İnce   +5 more
doaj   +1 more source

Synthesis, Crystal Structure and Antifungal Activity of (E)-1-(4-Methylbenzylidene)-4-(3-Isopropylphenyl) Thiosemicarbazone: Quantum Chemical and Experimental Studies

Molecules
A novel (E)-1-(4-methylbenzylidene)-4-(3-isopropylphenyl) thiosemicarbazone was synthesized in a one-pot four-step synthetic route. Fourier transform infrared spectroscopy (FTIR), 1H and 13C nuclear magnetic resonances (NMR), single-crystal X-ray ...
Haitao Ren, Fan Qi, Yuzhen Zhao, Abdelkader Labidi, Zongcheng Miao   +4 more
doaj   +1 more source

Enhanced Anticancer Potential of Pd(II)-Thiosemicarbazone Complexes: Selectivity, Mechanisms, and 3D Models

Pharmaceutics
Background/Objectives: Cancer remains a major global health challenge, driving the search for novel chemotherapeutic agents. This study aimed to evaluate the structural and biological properties of a series of Pd(II) complexes containing ...
Mauro A. Lima, Tamara Teixeira, Dario B. Fortaleza, George B. S. Pereira, Amos O. Akinyemi, Carlos André Ferreira Moraes, Moacir R. Forim, Alzir A. Batista, Jocely L. Dutra, João H. Araujo-Neto, Javier A. Ellena, Fillipe V. Rocha   +11 more
doaj   +1 more source

Mono- és bisz(acil)hidrazonok átalakulásai: Gyűrűs N,O,S-acetálok/ketálok szintézise. = Transformations of mono- and bis(acyl)hydrazones: Synthesis of cyclic N,O,S-acetals/ketals. [PDF]

, 2007
Aldehid- és keton-tioszemikarbazonokat állítottunk elő, melyeket acilezési körülmények között 3-acil-1,3,4-tiadiazolinokká ciklizáltunk. A 2-monoszubsztituált heterogyűrűs vegyületek oxidáló, illetve dehidrogénező szerek [kálium permanganát és a most ...
Somogyi, László
core  

Discovery of novel isatin-based thiosemicarbazones: synthesis, antibacterial, antifungal, and antimycobacterial screening

, 2020
Maryam Hassan, Reihaneh Baradaran Ghaffari, Soroush Sardari, Yekta Farmahini Farahani, Shohreh Mohebbi   +4 more
openalex   +1 more source

Thiosemicarbazonep-Substituted Acetophenone Derivatives Promote the Loss of MitochondrialΔψ, GSH Depletion, and Death in K562 Cells [PDF]

, 2015
Felipe S. Pessoto, César H. Yokomizo, Tatiana Prieto, Cleverton S. Fernandes, Alan Silva, Carlos R. Kaiser, Ernani A. Basso, Iseli L. Nantes   +7 more
openalex   +1 more source

Novel hybrid thiazoles, bis-thiazoles linked to azo-sulfamethoxazole: Synthesis, docking, and antimicrobial activity

Heliyon
The reaction of sulfamethoxazolehydrazonoyl chloride with thiosemicarbazones, bis-thiosemicarbazones, or 4-amino-3-mercapto-1,2,4-triazole in dioxane in the presence of triethylamine as a basic catalyst at reflux resulted in the regioselective synthesis ...
Mostafa E. Salem, Ismail A. Abdelhamid, Ahmed H.M. Elwahy, Mohamed A. Ragheb, Arwa sultan Alqahtani, Magdi E.A. Zaki, Faisal K. Algethami, Huda Kamel Mahmoud   +7 more
doaj   +1 more source