Results 91 to 100 of about 4,853 (201)

Computational Studies of Thiosemicarbazone-Based Metal Complexes and Their Biological Applications

Engineering Proceedings
Thiosemicarbazones are known for their versatile coordination behavior and wide-ranging applications in the field of materials science, catalysis, and medicinal chemistry.
Kulsum Hashmi, Satya, Priya Mishra, Ekhlakh Veg, Tahmeena Khan, Seema Joshi   +5 more
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Kinetic Insights into the Antioxidant Effect of Isatin-Thiosemicarbazone in Biodiesel Blends

Antioxidants
Biodiesel has several drawbacks, such as being prone to oxidation, having reduced stability, and having limited storage time. Antioxidants compatible with biodiesel are being used to address its drawbacks.
Nalan Türköz Karakullukçu, Halit Muğlu, Hasan Yakan, Volkan Murat Yılmaz, Sarmad Marah, İkbal Agah İnce   +5 more
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Synthesis, Crystal Structure and Antifungal Activity of (E)-1-(4-Methylbenzylidene)-4-(3-Isopropylphenyl) Thiosemicarbazone: Quantum Chemical and Experimental Studies

Molecules
A novel (E)-1-(4-methylbenzylidene)-4-(3-isopropylphenyl) thiosemicarbazone was synthesized in a one-pot four-step synthetic route. Fourier transform infrared spectroscopy (FTIR), 1H and 13C nuclear magnetic resonances (NMR), single-crystal X-ray ...
Haitao Ren, Fan Qi, Yuzhen Zhao, Abdelkader Labidi, Zongcheng Miao   +4 more
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Enhanced Anticancer Potential of Pd(II)-Thiosemicarbazone Complexes: Selectivity, Mechanisms, and 3D Models

Pharmaceutics
Background/Objectives: Cancer remains a major global health challenge, driving the search for novel chemotherapeutic agents. This study aimed to evaluate the structural and biological properties of a series of Pd(II) complexes containing ...
Mauro A. Lima, Tamara Teixeira, Dario B. Fortaleza, George B. S. Pereira, Amos O. Akinyemi, Carlos André Ferreira Moraes, Moacir R. Forim, Alzir A. Batista, Jocely L. Dutra, João H. Araujo-Neto, Javier A. Ellena, Fillipe V. Rocha   +11 more
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Comparison of metabolic pathways of different α-N-heterocyclic thiosemicarbazones

, 2018
Clinical failure of novel drugs is often related to their rapid metabolism and excretion. This highlights the importance of elucidation of their pharmacokinetic profile already at the preclinical stage of drug development.
Koellensperger, Gunda (Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna), Frensemeier, Lisa M. (Institute of Inorganic and Analytical Chemistry, University of Muenster), Kowol, Christian R. (Department of Inorganic Chemistry, Faculty of Chemistry, University of Vienna), Keppler, Bernhard K. (Department of Inorganic Chemistry, Faculty of Chemistry, University of Vienna), Pelivan, Karla (Department of Inorganic Chemistry, Faculty of Chemistry, University of Vienna), Heffeter, Petra (Institute of Cancer Research and Comprehensive Cancer Center, Medical University of Vienna), Karst, Uwe (Institute of Inorganic and Analytical Chemistry, University of Muenster)   +6 more
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Synthesis of Thiosemicarbazones of Some Aromatic Fluoro-Ketones as Potential Pesticides

, 1963
Synthesis of Thiosemicarbazones of Some Aromatic Fluoro-Ketones as Potential ...
K. C. Joshi, S. C. Bahel
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Regioisomeric oximes and thiosemicarbazones derived from 6-substituted pyridoxines

, 2020
The selective oxidation of 2- and 4-positioned hydroxymethyl groups of 6-methyl-2,3,4-tris(hydroxymethyl)pyridin-5-ol was developed and the thus obtained aldehydes were converted into their oximes and thiosemicarbazones.
Shtyrlin Y., Shtyrlin N., Lodochnikova O.   +2 more
core  

Regioselective N(2)-H-functionalization of thiosemicarbazones of aromatic and heteroaromatic aldehydes with acrylonitrile

, 2016
Regioselective N(2)-H-cyanoethylation of thiosemicarbazones of aromatic and heteroaromatic aldehydes with acrylonitrile proceeds under mild conditions (14% KOH, acetone/H2O, 35 °C, 6–21 h) to afford 1-(2-сyanoethyl)-2-[(E)-aryl(heteroaryl)methylidene]-1 ...
Svetlana V. Amosova (2194696), Boris A. Trofimov (723086), Anastasiya G. Mal’kina (834809), Valentina V. Nosyreva (3341618), Andrei V. Afonin (1964020), Alexander I. Albanov (2108407), Alexander V. Vashchenko (2624197)   +6 more
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Regioisomeric oximes and thiosemicarbazones derived from 6-substituted pyridoxines [PDF]

, 2012
The selective oxidation of 2- and 4-positioned hydroxymethyl groups of 6-methyl-2,3,4-tris(hydroxymethyl)pyridin-5-ol was developed and the thus obtained aldehydes were converted into their oximes and thiosemicarbazones.
Shtyrlin Y., Shtyrlin N., Lodochnikova O.   +2 more
core  

Design, synthesis, in vitro and in silico studies of novel piperidine derived thiosemicarbazones as inhibitors of dihydrofolate reductase

Scientific Reports
Dihydrofolate reductase (DHFR), an essential enzyme in folate metabolism, presents a promising target for drug development against various diseases, including cancer and tuberculosis.
Hina Aftab, Saeed Ullah, Ajmal Khan, Mariya al-Rashida, Talha Islam, Kholood A. Dahlous, Saikh Mohammad, Hamdy Kashtoh, Ahmed Al-Harrasi, Zahid Shafiq   +9 more
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