Results 111 to 120 of about 14,086 (252)

Synthesis, Antioxidant Activity, Acetylcholinesterase Inhibition and Quantum Studies of Thiosemicarbazones [PDF]

, 2018
Thiosemicarbazones are a class of compounds of interest for Medicinal Chemistry, as they are structurally diverse and have numerous biological activities reported in the literature.
Alessandra Mascarello (470305), Inês M. C. Brighente (842812), Aldo S. de Oliveira (4869475), Rosendo A. Yunes (786390), Ricardo J. Nunes (786389), Larissa Sens (4869478)   +5 more
core   +1 more source

Synthesis and Characterization of Some New Cu(II), Ni(II) and Zn(II) Complexes with Salicylidene Thiosemicarbazones: Antibacterial, Antifungal and in Vitro Antileukemia Activity

Molecules, 2013
Thirty two new Cu(II), Ni(II) and Zn(II) complexes (1–32) with salicylidene thiosemicarbazones (H2L1–H2L10) were synthesized. Salicylidene thiosemicarbazones, of general formula (X)N-NH-C(S)-NH(Y), were prepared through the condensation reaction of 2 ...
Tudor Rosu, Victor Tapcov, Donald Poirier, Elena Pahontu, Valeriu Fala, Aurelian Gulea   +5 more
doaj   +1 more source

SYNTHESIS AND BIOLOGICAL ACTIVITY OF COPPER(II) COORDINATION COMPOUNDS WITH 2-HYDROXY-1-NAPHTHALDEHYDE N(4)-ALLYL-3-THIOSEMICARBAZONE

Studia Universitatis Moldaviae: Stiinte reale si ale naturii, 2021
The paper presents the synthesis of the 2-hydroxy-1-naphthaldehyde N(4)-allyl-3-thiosemicarbazone (H2L) and seven coordination compounds of copper with this ligand and heteroaromatic amines.
Ianina ULCHINA, Victor TSAPKOV, Vasilii GRAUR, Aurelian GULEA   +3 more
doaj  

In Vitro and Ultrastructural Evaluation of the Cytotoxic and Antileishmanial Activities of Thiosemicarbazone Compounds Against Promastigotes and Axenic Amastigotes of Leishmania infantum

Tropical Medicine and Infectious Disease
Leishmaniasis remains a global health challenge, and the search for effective and selective therapeutic agents is crucial. This study evaluated the in vitro antileishmanial and cytotoxic activities of thiosemicarbazone compounds (LT-70, LT-73, LT-75, and
Janderson Weydson Lopes Menezes da Silva, Andréa Regina Alves da Rocha Diniz, Alberon Ribeiro de Araújo, Gabriel Gazzoni Araújo Gonçalves, Dyana Leal Veras, Marton Kaique de Andrade Cavalcante, Jana Messias Sandes, Iranildo José da Cruz Filho, Diego Santa Clara Marques, Maria do Carmo Alves de Lima, Ana Paula Sampaio Feitosa, Luiz Carlos Alves, Fábio André Brayner   +12 more
doaj   +1 more source

Regioisomeric oximes and thiosemicarbazones derived from 6-substituted pyridoxines [PDF]

, 2012
The selective oxidation of 2- and 4-positioned hydroxymethyl groups of 6-methyl-2,3,4-tris(hydroxymethyl)pyridin-5-ol was developed and the thus obtained aldehydes were converted into their oximes and thiosemicarbazones.
Shtyrlin Y., Shtyrlin N., Lodochnikova O.   +2 more
core  

Computational Studies of Thiosemicarbazone-Based Metal Complexes and Their Biological Applications

Engineering Proceedings
Thiosemicarbazones are known for their versatile coordination behavior and wide-ranging applications in the field of materials science, catalysis, and medicinal chemistry.
Kulsum Hashmi, Satya, Priya Mishra, Ekhlakh Veg, Tahmeena Khan, Seema Joshi   +5 more
doaj   +1 more source

Kinetic Insights into the Antioxidant Effect of Isatin-Thiosemicarbazone in Biodiesel Blends

Antioxidants
Biodiesel has several drawbacks, such as being prone to oxidation, having reduced stability, and having limited storage time. Antioxidants compatible with biodiesel are being used to address its drawbacks.
Nalan Türköz Karakullukçu, Halit Muğlu, Hasan Yakan, Volkan Murat Yılmaz, Sarmad Marah, İkbal Agah İnce   +5 more
doaj   +1 more source

Synthesis, Crystal Structure and Antifungal Activity of (E)-1-(4-Methylbenzylidene)-4-(3-Isopropylphenyl) Thiosemicarbazone: Quantum Chemical and Experimental Studies

Molecules
A novel (E)-1-(4-methylbenzylidene)-4-(3-isopropylphenyl) thiosemicarbazone was synthesized in a one-pot four-step synthetic route. Fourier transform infrared spectroscopy (FTIR), 1H and 13C nuclear magnetic resonances (NMR), single-crystal X-ray ...
Haitao Ren, Fan Qi, Yuzhen Zhao, Abdelkader Labidi, Zongcheng Miao   +4 more
doaj   +1 more source

Enhanced Anticancer Potential of Pd(II)-Thiosemicarbazone Complexes: Selectivity, Mechanisms, and 3D Models

Pharmaceutics
Background/Objectives: Cancer remains a major global health challenge, driving the search for novel chemotherapeutic agents. This study aimed to evaluate the structural and biological properties of a series of Pd(II) complexes containing ...
Mauro A. Lima, Tamara Teixeira, Dario B. Fortaleza, George B. S. Pereira, Amos O. Akinyemi, Carlos André Ferreira Moraes, Moacir R. Forim, Alzir A. Batista, Jocely L. Dutra, João H. Araujo-Neto, Javier A. Ellena, Fillipe V. Rocha   +11 more
doaj   +1 more source

Transition metal complexes derived from ketone based N(4)-substituted thiosemicarbazones: Crystal structures and spectral studies [PDF]

, 2012
Thiosemicarbazones have recently attracted considerable attention due to their ability to form tridentate chelates with transition metal ions through either two nitrogen and sulfur atoms, N–N–S or oxygen, nitrogen and sulfur atoms, O–N–S.
Renjusha, S, Dr.Prathapachandra Kurup,M R   +1 more
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