Synthesis, antidiabetic evaluation, and computational modeling of 3-acetyl-8-ethoxy coumarin derived hydrazones and thiosemicarbazones. [PDF]
Zareen W +10 more
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Reactivity of Acetylbarbituric Thiosemicarbazone Derivatives with Silver(I) Nitrate and the Influence of Substituents at Nitrogen Atom 4N on the Bonding and Nuclearity of the Resulting Silver(I) Complexes. [PDF]
Castiñeiras A +4 more
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Arylidenehydrazinyl 4-Methylthiazole-5-carboxylates: Synthesis, Antileishmanial Activity, and Targeting of Trypanothione Synthetase. [PDF]
Souza BDS +14 more
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Research progress on the application of multi-scale computational methods in the research and development of anti-tuberculosis infection drugs. [PDF]
Zhao Y +5 more
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In Silico Docking and Spectroscopic Evaluation of a Thiocarbohydrazone Derivative: Structural Elucidation and Enzyme Inhibitory Mechanisms. [PDF]
Karatzia M +6 more
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Thiosemicarbazones as versatile photoswitches with light-controllable supramolecular activity. [PDF]
Sentürk B, Butschke B, Eisenreich F.
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Chalcogen substitution co-tunes photochromism and hydrogen bonding in semicarbazone photoswitches. [PDF]
Sentürk B +4 more
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Corrigendum to "Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2- Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling". [PDF]
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Synthesis and Anticancer Activity of Thiosemicarbazones
Bioorganic and Medicinal Chemistry Letters, 2006Twenty-six thiosemicarbazones (III-1-III-26) were synthesized via three steps starting from hydrazine hydrate and carbon disulfide. The testing of anticancer activity of these compounds in vitro against P-388, A-549, and SGC-7901 shows that compounds III-15 and III-16 possess a higher inhibitory ability for P-388 and SGC-7901.
Xia Chun-nian, Xi Wen, Wei-Xiao Hu
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