Results 1 to 10 of about 9,384 (213)

From Design to Bioactivity: 2‐Benzoylpyridine 4‐(bicyclo[2.2.1]hept‐2‐yl)thiosemicarbazone and Its 3d Metal Coordination Compounds [PDF]

ChemistryOpen
The new 2‐benzoylpyridine 4‐(bicyclo[2.2.1]hept‐2‐yl)thiosemicarbazone (HL) and its copper(II), nickel(II), cobalt(III), and iron(III) coordination compounds [Cu(L)Cl] (1), [Cu(L)NO3] (2), {[Cu(L)(Cl2CHCOO)]}n (3), [Ni(HL)2](NO3)2 (4), [Fe(L)2]NO3 (5 ...
Ianina Graur, Vasilii Graur, Elena Melnic, Carolina Lozan‐Tirsu, Greta Balan, Victor Tsapkov, Aurelian Gulea   +6 more
doaj   +2 more sources

Anti-infective macrozones: design, biological evaluation and structure-activity relationships [PDF]

ADMET and DMPK
Background and purpose: To discover novel compounds active against sensitive and resistant bacterial strains, a series of novel azithromycin-thiosemicarbazone conjugates, the macrozones, have been syn­the­sized and their biological activity evaluated ...
Tomislav Jednačak, Višnja Stepanić, Iva Habinovec, Ivana Mikulandra, Kristina Smokrović, Hana Čipčić Paljetak, Mirjana Bukvić, Jelena Parlov Vuković, Ivan Grgičević, Leda Divjak, Klaus Zangger, Predrag Novak   +11 more
doaj   +2 more sources

Inhibition behaviour of mild steel by three new benzaldehyde thiosemicarbazone derivatives in 0.5 M H2SO4: experimental and computational study [PDF]

Royal Society Open Science, 2019
Three new benzaldehyde thiosemicarbazone derivatives namely benzaldehyde thiosemicarbazone (BST), 4-carboxyl benzaldehyde thiosemicarbazone (PBST) and 2-carboxyl benzaldehyde thiosemicarbazone (OCT) were synthesized and their inhibition effects on mild ...
H. H. Zhang, C. K. Qin, Y. Chen, Z. Zhang   +3 more
doaj   +1 more source

X-ray Diffraction Study of Fluorine-Functionalized Thiosemicarbazones and Cyclometallated Compounds

Chemistry Proceedings, 2022
In this work, an X-ray diffraction study of fluorine-functionalized thiosemicarbazone ligands and their corresponding cyclometallated compounds is discussed.
Marcos Rúa-Sueiro, Paula Munín-Cruz, Juan M. Ortigueira, José M. Vila   +3 more
doaj   +1 more source

Novel Thiosemicarbazone Derivatives from Furan-2-Carbaldehyde: Synthesis, Characterization, Crystal Structures, and Antibacterial, Antifungal, Antioxidant, and Antitumor Activities

Journal of Chemistry, 2023
Ten new thiosemicarbazone derivatives, furan-2-carbaldehyde thiosemicarbazone (1), 3-methyl-furan-2-carbaldehyde thiosemicarbazone (2), 5-hydroxymethyl-furan-2-carbaldehyde thiosemicarbazone (3), 5-trifluoromethyl-furan-2-carbaldehyde thiosemicarbazone ...
Wilfredo Hernández, Fernando Carrasco, Abraham Vaisberg, Evgenia Spodine, Maik Icker, Harald Krautscheid, Lothar Beyer, Carmen Tamariz-Angeles, Percy Olivera-Gonzales   +8 more
doaj   +1 more source

The antimicrobial activity of lapachol and its thiosemicarbazone and semicarbazone derivatives

Memorias do Instituto Oswaldo Cruz, 2013
Lapachol was chemically modified to obtain its thiosemicarbazone and semicarbazone derivatives. These compounds were tested for antimicrobial activity against several bacteria and fungi by the broth microdilution method.
Marina Azevedo Souza, Susana Johann, Luciana Alves Rodrigues dos Santos Lima, Fernanda Fraga Campos, Isolda Castro Mendes, Heloisa Beraldo, Elaine Maria de Souza-Fagundes, Patricia Silva Cisalpino, Carlos Augusto Rosa, Tania Maria de Almeida Alves, Nivea Pereira de Sa, Carlos Leomar Zani   +11 more
doaj   +3 more sources

An UHPLC-TOF-MS method for quantifying novel brominated anticancer compound bromophenol-thiosemicarbazone hybrid and its application to in vivo pharmacokinetic study

Journal of Analytical Science and Technology, 2020
Background Bromophenol-thiosemicarbazone hybrid was a novel synthetic brominated anticancer compound with two bromine atoms. Bromophenol-thiosemicarbazone hybrid showed considerable selective inhibitory activity against PARP1 (IC50 = 29.5 nmol/L).
Xiuxue Li, Lijun Wang, Xiaoling Jia, Chuanlong Guo, Chao Li, Jiajia Zhang, Dayong Shi   +6 more
doaj   +1 more source

Synthesis and Characterization of Novel Thiazolidinones and Thioxothiazolidinones Derived from Substituted Indole

Molbank, 2021
Based on recent discoveries concerning the numerous biological properties of thiazolidinones and thiosemicarbazones, new N-substituted heterocyclic derivatives have been designed by combining the indole ring with thioxothiazolidinone, thiazolidinone or ...
Nawel Rekiba, Abdelmadjid Benmohammed, Sofiane Khanoussi, Ayada Djafri, Jérôme Thibonnet   +4 more
doaj   +1 more source

Half-Sandwich Arene Ruthenium(II) Thiosemicarbazone Complexes: Evaluation of Anticancer Effect on Primary and Metastatic Ovarian Cancer Cell Lines

Frontiers in Pharmacology, 2022
In this study, we describe the synthesis, characterization and antiproliferative activity of three organo-ruthenium(II) half-sandwich complexes [RuCl(η6-p-cym)(N,S-L)]Cl (I, II, and III).
Seminay Guler, Seminay Guler, Hulya Ayar Kayali, Hulya Ayar Kayali, Hulya Ayar Kayali, Egemen Orkun Sadan, Betul Sen, Elif Subasi   +7 more
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Quantum Chemical Studies on the Corrosion Inhibition of Fe78B13Si9 glassy alloy in Na2SO4 Solution of Some Thiosemicarbazone Derivatives

International Journal of Electrochemical Science, 2018
In this study, the density functional theory (DFT) at the gradient-corrected correlation functional of Lee-Yang-Parr (B3LYP) functional with 6-311++G(2d,2p), correlation-consistent, polarized valence, X-zeta (cc-pVTZ) basis sets, BP86 functional with/6 ...
Murat Saraçoğlu, Mahmooud Ibrahim A. Elusta, Savaş Kaya, Cemal Kaya, Fatma Kandemirli   +4 more
doaj   +1 more source