Results 81 to 90 of about 4,853 (201)

Evaluation of Some Thiosemicarbazones as Potential Antileishmanial Agents

, 2014
- A series of thiosemicarbazones 1-6 derived from 2-benzoylthiophene, 2-furaldehyde, thiophene-2-carboxaldehyde, 4-dimethylaminobenzaldehyde, 4-methoxybenzaldehyde and 4-hydroxy-3-methoxybenzaldehyde were prepared by condensation of ketones and / or ...
Nizam Baloch, Hassan M. F. Madkour, Y. Farina, Yasser M. S. A. Al-kahraman   +3 more
core  

Synthesis and Structural Characterization of Fluorinated Thiosemicarbazones

, 2013
Six new fluorinated thiosemicarbazones R‑C(R′)=N-NH-C(S)NH2 (R = 2,4-C6H3F2, R′ = H (1); R = 2,5-C6H3F2, R′ = H (2); R = 2,6-C6H3F2, R′ = H (3); R = 3,4-C6H3F2, R′ = H (4); R = 3,5-C6H3F2, R′ = H (5) and R = 4-C6H4F, R′ = C6H5, (6)) have been prepared ...
Jorge Tiburcio, Marcos Flores-Alamo, Juan Bautista, Rebeca Vieto, Juan L. Bautista, Hugo Torrens   +5 more
core   +1 more source

Synthesis, antibacterial activity and DNA interactions of lanthanide(III) complexes of N(4)-substituted thiosemicarbazones

Universitas Scientiarum, 2018
This paper reports the synthesis and detailed characterization of six novel lanthanide complexes of La(III), Eu(III) and Nd(III) with N(4)-substituted thiosemicarbazones derived from the 2-carboxybenzaldehyde.
Juan-David Londoño-Mosquera, Alberto Aragón-Muriel, Dorian Polo Cerón   +2 more
doaj   +1 more source

Thiosemicarbazones suppress expression of the c-Met oncogene by mechanisms involving lysosomal degradation and intracellular shedding

, 2020
Considering the role of proto-oncogene c-Met (c-Met) in oncogenesis, we examined the effects of the metastasis suppressor, N-myc downstream-regulated gene-1 (NDRG1), and two NDRG1-inducing thiosemicarbazone-based agents, Dp44mT and DpC, on c-Met ...
Geleta, B, Richardson, DR, Jansson, PJ, Leck, LYW, Paluncic, J, Chiang, S, Park, KC, Kovacevic, Z   +7 more
core   +1 more source

Crystal structure of (2E)-N-methyl-2-(2-oxo-1,2-dihydroacenaphthylen-1-ylidene)hydrazinecarbothioamide

Acta Crystallographica Section E, 2014
In the title compound, C14H11N3OS, the acenaphthylene ring system and hydrazinecarbothioamide unit (=N—NH—C=S—NH–) are essentially coplanar [with maximum deviations from their mean planes of −0.009 (2) and 0.033 (2) Å, respectively], and make a dihedral ...
G. Vimala, J. Govindaraj, J. Haribabu, R. Karvembu, A. SubbiahPandi   +4 more
doaj   +1 more source

Functionalized thiosemicarbazone ligands and their complexes.

Proceedings of The 20th International Electronic Conference on Synthetic Organic Chemistry, 2016
The purpose of this work is the design, synthesis and characterization of thiosemicarbazone ligands bearing a phenyl boronic acid functionality. The main interest is the synthesis of organopalladium compounds with the boronic acid included within the corresponding molecule.
Reigosa Chamorro, Francisco, Lucio Martínez, Fátima, Fernández Figueiras, Adolfo, Munín Cruz, Paula, Vila Abad, José Manuel, Pereira Lorenzo, María Teresa, Frieiro Gomis, Pablo Juan   +6 more
openaire   +2 more sources

Targeting redox balance: antioxidant effects of thiosemicarbazones on human peripheral blood

Introduction. Thiosemicarbazones represent a class of organic compounds with well-documented pharmacological properties, including antitumor, antimicrobial, and antiviral activities.
Pavlovschi, Ecaterina, Pantea, Valeriana, Gudumac, Valentin, Gulea, Aurelian, Stratulat, Silvia, Tagadiuc, Olga   +5 more
core   +1 more source

SYNTHESIS AND BIOLOGICAL ACTIVITY OF COPPER(II) COORDINATION COMPOUNDS WITH 2-HYDROXY-1-NAPHTHALDEHYDE N(4)-ALLYL-3-THIOSEMICARBAZONE

Studia Universitatis Moldaviae: Stiinte reale si ale naturii, 2021
The paper presents the synthesis of the 2-hydroxy-1-naphthaldehyde N(4)-allyl-3-thiosemicarbazone (H2L) and seven coordination compounds of copper with this ligand and heteroaromatic amines.
Ianina ULCHINA, Victor TSAPKOV, Vasilii GRAUR, Aurelian GULEA   +3 more
doaj  

Rhodium assisted C-H activation of benzaldehyde thiosemicarbazones and their oxidation via activation of molecular oxygen

, 2006
The benzaldehyde thiosemicarbazones are found to undergo oxidation at the sulfur center upon reaction with [Rh(PPh3)3Cl] in refluxing ethanol in the presence of a base (NEt3).
Falvello, Larry. R., Bhattacharya, Samaresh, Acharyya, Rama, Dutta, Swati, Peng, Shie-Ming, Lee, Gene-Hsiang, Basuli, Falguni   +6 more
core   +1 more source

In Vitro and Ultrastructural Evaluation of the Cytotoxic and Antileishmanial Activities of Thiosemicarbazone Compounds Against Promastigotes and Axenic Amastigotes of Leishmania infantum

Tropical Medicine and Infectious Disease
Leishmaniasis remains a global health challenge, and the search for effective and selective therapeutic agents is crucial. This study evaluated the in vitro antileishmanial and cytotoxic activities of thiosemicarbazone compounds (LT-70, LT-73, LT-75, and
Janderson Weydson Lopes Menezes da Silva, Andréa Regina Alves da Rocha Diniz, Alberon Ribeiro de Araújo, Gabriel Gazzoni Araújo Gonçalves, Dyana Leal Veras, Marton Kaique de Andrade Cavalcante, Jana Messias Sandes, Iranildo José da Cruz Filho, Diego Santa Clara Marques, Maria do Carmo Alves de Lima, Ana Paula Sampaio Feitosa, Luiz Carlos Alves, Fábio André Brayner   +12 more
doaj   +1 more source