Results 211 to 220 of about 14,165 (252)

Hydroxyalkyne-Bithiophene Derivatives: Synthesis and Antileishmanial Activity. [PDF]

Chem Biol Drug Des
Machado RRB, Salvador DL, Gomes CMB, Bakoshi ABK, Ueda-Nakamura T, de Oliveira Silva S, Nakamura CV, Sarragiotto MH, Lazarin-Bidóia D.   +8 more
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A glimpse into the developments, potential leads and future perspectives of anticancer cobalt complexes. [PDF]

RSC Med Chem
Khursheed A, Khursheed N, Rashid N, Khanday WA, Hussain A, Alajmi MF, Amir S, Malik AH, Rather JA, Wani AH, Ahmad J, Hussain I, Iqbal PF, Wani WA.   +13 more
europepmc   +1 more source

Targeting lysosomes by design: novel N-acridine thiosemicarbazones that enable direct detection of intracellular drug localization and overcome P-glycoprotein (Pgp)-mediated resistance. [PDF]

Chem Sci
Kaya B, Smith H, Chen Y, Azad MG, M Russell T, Richardson V, Bernhardt PV, Dharmasivam M, Richardson DR.   +8 more
europepmc   +1 more source

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Antifungal activity of thiosemicarbazones, bis(thiosemicarbazones), and their metal complexes

Journal of Inorganic Biochemistry, 2021
Fungi are ubiquitous in nature, and typically cause little or no environmental or pathogenic damage to their plant, animal, and human hosts. However, a small but growing number of pathogenic fungi are spreading world-wide at an alarming rate threatening global ecosystem health and proliferation.
Kritika, Bajaj, Robert M, Buchanan, Craig A, Grapperhaus   +2 more
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Structure of salicylaldehyde thiosemicarbazone

Acta Crystallographica Section C Crystal Structure Communications, 1988
C8H9N3OS, monoclinic, C2/c, a = 14.206 (3), b = 14.244 (4), c = 10.457 (4) A, beta = 116.18(2) degrees, V = 1898.9 (8) A3, Z = 8, Dm = 1.387, D chi = 1.366 g cm-3, lambda(Mo K alpha) = 0.71069 A, mu = 2.90 cm-1, F(000) = 816.0, T = 298 K, final R = 0.0429 for 1322 observed reflections. The S and hydrazinic N atoms lie trans.
D, Chattopadhyay, S K, Mazumdar, T, Banerjee, S, Ghosh, T C, Mak   +4 more
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Biodistribution of 59Fe-thiosemicarbazones

International Journal of Nuclear Medicine and Biology, 1982
The 59Fe-iron(II) chelates of 2-formylpyridine thiosemicarbazone (I), 5-dimethylamino-2-formylpyridine thiosemicarbazone (II), and 5-hydroxy-2-formylpyridine thiosemicarbazone (III) were prepared and their biodistribution determined in normal rats. Early accumulation of these complexes occurred in the liver, muscle and pelt with lesser amounts in the ...
R N, Hanson, M A, Davis
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Semicarbazones and thiosemicarbazones. VII. Structure of 2-hydroxyacetophenone thiosemicarbazone

Acta Crystallographica Section C Crystal Structure Communications, 1988
Cristallisation dans P 21n avec affinement jusqu'a 0,042. L'atome S est situe en trans par rapport a l'atome N du groupe hydrazine.
M. Soriano-García, J. Valdés-Martínez, R. A. Toscano   +2 more
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Thiosemicarbazone und Hyaluronidase

Naunyn-Schmiedebergs Archiv f�r Experimentelle Pathologie und Pharmakologie, 1952
Es wurde gepruft, ob dem antirheumatischen Effekt der Thiosemicarbazonwirkungen auf das Hyaluronsaure-Hyaluronidase-System zugrunde liegen, wie dies von anderen stark antirheumatisch wirkenden Substanzen bekannt ist. 1. Im Viscositatsminderungs-Test zeigte lediglich Solvoteben eine Hemmung der Hyaluronidase in Konzentrationen, wie sie im ...
H. Rohkr�mer, W. Wernitz
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Antimicrobial Properties of Aliphatic Thiosemicarbazones

Journal of Pharmaceutical Sciences, 1964
A series of thiosemicarbazones of saturated and α,β-unsaturated aliphatic aldehydes was prepared and tested in vitro for activity against various bacteria, yeasts, and molds. Antimicrobial potency was found to depend on chain length and was greatly enhanced by the presence of an unsaturated linkage.
M, MANOWITZ, G, WALTER
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Thiosemicarbazones derived from indanedione-1, 3

Journal of Pharmaceutical Sciences, 1967
A series of thiosemicarbazones derived from indanedione-1, 3 has been synthesized. Preliminary biological screening data are provided.
R S, Varma, W L, Nobles
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