Results 61 to 70 of about 3,211 (192)

Hydrogen Sulfide Prevents Mesenteric Adipose Tissue Damage, Endothelial Dysfunction, and Redox Imbalance From High Fructose Diet-Induced Injury in Aged Rats

Frontiers in Pharmacology, 2021
A high fructose diet (HFD) and advanced age are key factors for the gradual loss of physiological integrity of adipose tissue. Endogenous hydrogen sulfide (H2S) has beneficial effects on cytoprotection and redox balance.
Oleh Revenko, Yaroslav Pavlovskiy, Maryana Savytska, Antonina Yashchenko, Vasyl Kovalyshyn, Ilona Chelpanova, Olena Varyvoda, Oksana Zayachkivska   +7 more
doaj   +1 more source

A Proteomic Approach to Study the Effect of Thiotaurine on Human Neutrophil Activation [PDF]

, 2017
Thiotaurine, a thiosulfonate related to taurine and hypotaurine, is formed by a metabolic process from cystine and generated by a transulfuration reaction between hypotaurine and thiocysteine.
A Ferrante, AK Mustafa, B Sörbo, BD Paul, BD Paul, C De Marco, C De Marco, D Cavallini, D Cavallini, D Cavallini, DB Learn, E Capuozzo, E Capuozzo, E Cuevasanta, EG Mueller, F Di Domenico, GX Luo, H Beinert, H Kimura, J Dragotto, J Westley, JI Toohey, JI Toohey, L Cattaneo, M Whiteman, M Whiteman, MR Hara, O Kabil, PK Yadav, RCO Zanardo, S Canterini, S Singh, TR Chauncey, TV Mishanina   +33 more
core   +2 more sources

H2S Donors Reverse Age-Related Gastric Malfunction Impaired Due to Fructose-Induced Injury via CBS, CSE, and TST Expression

Frontiers in Pharmacology, 2020
ObjectiveExcess of fructose consumption is related to life-treating conditions that affected more than a third of the global population. Therefore, to identify a newer therapeutic strategy for the impact prevention of high fructose injury in age-related ...
Yaroslav Pavlovskiy, Antonina Yashchenko, Oksana Zayachkivska   +2 more
doaj   +1 more source

Full-Length Transcriptome Comparison Provides Novel Insights into the Molecular Basis of Adaptation to Different Ecological Niches of the Deep-Sea Hydrothermal Vent in Alvinocaridid Shrimps

Diversity, 2022
The deep-sea hydrothermal vent ecosystem is one of the extreme chemoautotrophic environments. Shinkaicaris leurokolos Kikuchi and Hashimoto, 2000, and Alvinocaris longirostris Kikuchi and Ohta, 1995, are typically co-distributed and closely related ...
Aiyang Wang, Zhongli Sha, Min Hui
doaj   +1 more source

Cytoplasmic sulfurtransferases in the purple sulfur bacterium Allochromatium vinosum: evidence for sulfur transfer from DsrEFH to DsrC. [PDF]

PLoS ONE, 2012
While the importance of sulfur transfer reactions is well established for a number of biosynthetic pathways, evidence has only started to emerge that sulfurtransferases may also be major players in sulfur-based microbial energy metabolism.
Yvonne Stockdreher, Sofia S Venceslau, Michaele Josten, Hans-Georg Sahl, Inês A C Pereira, Christiane Dahl   +5 more
doaj   +1 more source

NRF2 signalling in cytoprotection and metabolism

British Journal of Pharmacology, Volume 183, Issue 1, Page 101-114, January 2026.
The KEAP1‐NRF2 system plays a central role in cytoprotection in defence mechanisms against oxidative stress. The KEAP1‐NRF2 system has been regarded as a sulfur‐utilizing cytoprotective mechanism, because KEAP1 serves as a biosensor for electrophiles by using its reactive thiols and NRF2 is a transcriptional factor regulating genes involved in sulfur ...
Shohei Murakami, Yusuke Kusano, Keito Okazaki, Takaaki Akaike, Hozumi Motohashi   +4 more
wiley   +1 more source

The Role of Sulfide Oxidation Impairment in the Pathogenesis of Primary CoQ Deficiency

Frontiers in Physiology, 2017
Coenzyme Q (CoQ) is a lipid present in all cell membranes. One of the multiple metabolic functions of CoQ is to transport electrons in the reaction catalyzed by sulfide:quinone oxidoreductase (SQOR), the first enzyme of the oxidation pathway of sulfides (
Catarina M. Quinzii, Marta Luna-Sanchez, Marta Luna-Sanchez, Marcello Ziosi, Agustin Hidalgo-Gutierrez, Giulio Kleiner, Luis C. Lopez   +6 more
doaj   +1 more source

Altered protein expression and protein nitration pattern during d-galactosamine-induced cell death in human hepatocytes: a proteomic analysis [PDF]

, 2005
BACKGROUND/AIMS: Hepatic injury by d-galactosamine (d-GalN) is a suitable experimental model of hepatocellular injury. The induction of oxidative and nitrosative stress participates during d-GalN-induced cell death in cultured rat hepatocytes.
Bernardos, A. (Angel), Corrales, F.J. (Fernando José), Gonzalez, R. (Raúl), Lopez-Casas, P. (Pedro), Lopez-Sanchez, L.M. (Laura M.), Muntane, J. (Jordi), Rodriguez-Ariza, A. (Antonio)   +6 more
core   +1 more source

Supersulfide biology and translational medicine for disease control

British Journal of Pharmacology, Volume 183, Issue 1, Page 115-130, January 2026.
Abstract For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial respiratory chain, contributing to energy production in aerobic organisms. In addition, oxygen‐derived reactive oxygen species including hydrogen peroxide and nitrogen
Uladzimir Barayeu, Tomohiro Sawa, Motohiro Nishida, Fan‐Yan Wei, Hozumi Motohashi, Takaaki Akaike   +5 more
wiley   +1 more source

Co-Cultures of Pseudomonas aeruginosa and Roseobacter denitrificans Reveal Shifts in Gene Expression Levels Compared to Solo Cultures

The Scientific World Journal, 2012
Consistent biosynthesis of desired secondary metabolites (SMs) from pure microbial cultures is often unreliable. In a proof-of-principle study to induce SM gene expression and production, we describe mixed “co-culturing” conditions and monitoring of ...
Crystal A. Conway, Nwadiuto Esiobu, Jose V. Lopez   +2 more
doaj   +1 more source