Results 71 to 80 of about 1,815 (145)
High protein diet reduced visceral adipose tissue through MTA‐TST‐Bak/Casp‐3 axis, suggesting that MTA has the potential to be developed as a functional substance for obesity prevention and control. ABSTRACT To explore the mechanism of a high‐protein diet (named high protein and rich fat diet, HPRFD) with weight loss effect regulating visceral fat ...
Xinli Yang +5 more
wiley +1 more source
Redirecting Intermediary Metabolism to Counteract Cyanide Poisoning
Cyanide is coined “the classic metabolic poison”; however, FDA‐approved cyanide chelators do not counteract cyanide's metabolic damage. Here, we review the mechanisms of cyanide toxicity, with a focus on intermediary metabolism. We present the theory that, within the innate plasticity of the metabolome, there may reside metabolic pathways that can ...
Vik S. Bebarta, Anjali K. Nath
wiley +1 more source
Fire‐related smoke inhalation‐induced acute lung injury (SI‐ALI) poses a significant public health risk, yet effective treatments are limited due to the lack of suitable models. This study developed a more realistic model of SI‐ALI using organ‐on‐a‐chip and organoid technologies, identified key molecules such as catechol‐O‐methyltransferase and ...
Junmin Li +12 more
wiley +1 more source
The physiological and biochemical mechanisms on boron (B)-induced alleviation of aluminum (B)-toxicity in plants have been examined in some details, but our understanding of the molecular mechanisms underlying these processes is very limited.
Xin-Xing Zhou +4 more
doaj +1 more source
The cyclic AMP receptor protein family of transcription factors regulates various metabolic pathways in bacteria, and also play roles in response to environmental changes.
Su Yang +9 more
doaj +1 more source
Role of hydrogen sulfide in health and disease
Abstract In the past, hydrogen sulfide (H2S) was recognized as a toxic and dangerous gas; in recent years, with increased research, we have discovered that H2S can act as an endogenous regulatory transmitter. In mammals, H2S‐catalyzing enzymes, such as cystathionine‐β‐synthase, cystathionine‐γ‐lyase, and 3‐mercaptopyruvate sulfurtransferase, are ...
Yu‐Qing Jin +9 more
wiley +1 more source
Abstract Our aim is to present an updated overview of the erythrocyte metabolism highlighting its richness and complexity. We have manually collected and connected the available biochemical pathways and integrated them into a functional metabolic map.
Panagiotis N. Chatzinikolaou +7 more
wiley +1 more source
Background The hepatoprotective potential of Phellinus linteus polysaccharide (PLP) extracts has been described. However, the molecular mechanism of PLP for the inhibition of liver fibrosis is unclear. This study aims to investigate the molecular protein
Wang Hualin +6 more
doaj +1 more source
Bacterial Isothiocyanate Biosynthesis by Rhodanese‐Catalyzed Sulfur Transfer onto Isonitriles
A novel biosynthetic pathway towards isothiocyanate natural products is identified. In vivo and in vitro biotransformation show that rhodanese‐like proteins (Rhd), known for the detoxification of cyanide, have been recruited and neofunctionalized to catalyze sulfur incorporation into isonitriles in bacteria.
Mandy D. Mlotek +2 more
wiley +1 more source
Advances in Gas Therapeutics for Wound Healing: Mechanisms, Delivery Materials, and Prospects
Therapeutic gases, such as oxygen, nitric oxide, carbon monoxide, and hydrogen sulfide, have transitioned from pure gases to inorganic/organic materials as gas‐releasing materials, including gas‐producing and gas‐loaded materials and controlled/long‐lasting stable‐releasing biomaterials for biomedical application in wound healing.
Jiayi Ding +5 more
wiley +1 more source

