Results 71 to 80 of about 3,211 (192)

Hydrogen Sulfide and Polysulfides as Biological Mediators

Molecules, 2014
Hydrogen sulfide (H2S) is recognized as a biological mediator with various roles such as neuromodulation, regulation of the vascular tone, cytoprotection, anti-inflammation, oxygen sensing, angiogenesis, and generation of mitochondrial energy.
Hideo Kimura
doaj   +1 more source

Cyanide Beyond Toxicity: A Systematic Review of Its Effects on Vascular Function

Basic &Clinical Pharmacology &Toxicology, Volume 137, Issue 5, November 2025.
ABSTRACT Cyanide is widely recognized for its potent toxicity, yet evidence shows that concentrations below 1 μM may enhance cytochrome c oxidase activity and have a regulatory function. Recent findings also demonstrate that mammalian cells, including endothelial cells, produce cyanide endogenously, where it can modulate mitochondrial bioenergetics ...
Elif Alan‐Albayrak, Ulf Simonsen
wiley   +1 more source

Dimethyl Sulfoxide (DMSO) as a Potential Source of Interference in Research Related to Sulfur Metabolism—A Preliminary Study

Antioxidants
Dimethyl sulfoxide (DMSO), an organosulfur compound, is widely used as the gold standard solvent in biological research. It is used in cell culture experiments and as a component of formulations in in vivo studies.
Marta Kaczor-Kamińska, Kinga Kaszuba, Anna Bilska-Wilkosz, Małgorzata Iciek, Maria Wróbel, Kamil Kamiński   +5 more
doaj   +1 more source

Cysteine Signalling in Plant Pathogen Response

Plant, Cell &Environment, Volume 48, Issue 10, Page 7107-7122, October 2025.
ABSTRACT The amino acid cysteine is the precursor for a wide range of sulfur‐containing functional molecules in plants, including enzyme cofactors and defence compounds. Due to its redox active thiol group cysteine is highly reactive. Synthesis and degradation pathways are present in several subcellular compartments to adjust the intracellular cysteine
Jannis Moormann, Björn Heinemann, Cecile Angermann, Anna Koprivova, Ute Armbruster, Stanislav Kopriva, Tatjana M. Hildebrandt   +6 more
wiley   +1 more source

Mitochondrial and nuclear localization of a novel pea thioredoxin: identification of its mitochondrial target proteins [PDF]

, 2009
Plants contain several genes encoding thioredoxins (Trxs), small proteins involved in the regulation of the activity of many enzymes through dithiol-disulfide exchange.
Marti, Maria C., Olmos, Enrique, Calvete, Juan J., Diaz Rodriguez, Isabel, Barranco Medina, Sergio, Whelan, James, Lazaro, Juan J., Sevilla, Francisca, Jimenez, Ana   +8 more
core   +1 more source

MTA‐TST Axis‐Mediated Apoptosis Activation: A Multi‐Omics Insight Into High‐Protein Diet's Anti‐Adiposity Effect

Food Science &Nutrition, Volume 13, Issue 7, July 2025.
High protein diet reduced visceral adipose tissue through MTA‐TST‐Bak/Casp‐3 axis, suggesting that MTA has the potential to be developed as a functional substance for obesity prevention and control. ABSTRACT To explore the mechanism of a high‐protein diet (named high protein and rich fat diet, HPRFD) with weight loss effect regulating visceral fat ...
Xinli Yang, Yueyue Wang, Zhe Shi, Aiting Wang, Jianglan Long, Dan Yan   +5 more
wiley   +1 more source

H2S biosynthesis and catabolism: new insights from molecular studies [PDF]

, 2017
Hydrogen sulfide (H2S) has profound biological effects within living organisms and is now increasingly being considered alongside other gaseous signalling molecules, such as nitric oxide (NO) and carbon monoxide (CO).
A Asimakopoulou, A Badiei, A Badiei, A Calderwood, A Jamroz-Wiśniewska, A Kalani, A Madurga, A Papapetropoulos, A Sun, AA Untereiner, AD Ang, AF Kamath, AF Perna, AF Perna, AK Mustafa, AL King, B Calenic, B Fox, B Gemici, B Gemici, B Geng, B Geng, B Qabazard, B Qabazard, B Szczesny, BD Paul, BJ Henriques, C Coletta, C Hine, C Hine, C Konrad, C Köhn, C Maestro de las Casas, C Steegborn, C Szabo, C Yang, CW Huang, D Liang, D Liao, DA Wing, DC Croteau-Chonka, DI Zafeiriou, DL Miller, DW Porter, DW Porter, E Albertini, E Grambow, E Lagoutte, EG Lynn, EG Mueller, EG Shesely, EM Bos, F Talaei, FL Zhao, G Chwatko, G Szabo, G Tang, G Tang, G Wang, G Yang, G Yang, G Yang, G Yang, G Yang, G Yang, G Yang, G Yang, G Yang, G Zagli, G Zhang, GA Benavides, GD Yang, GK Kolluru, GV Velmurugan, H Duplain, H Jang, H Jurkowska, H Kabil, H Li, H Shi, H Zhang, HB Roman, HG Lee, HL Jiang, HS Jin, I Baiges, I Billaut-Laden, I Hirata, I Ishii, I Meo Di, I Ueki, J Cai, J Candela, J Ereño-Orbea, J Hamelet, J Hamelet, J Wang, J Wang, JB Vicente, JD Finkelstein, JG Vande Weghe, JJ Li, JL Meng, JL Wallace, JN Mayo, JT Brosnan, JW Calvert, JW Elrod, JW Horsman, K Eto, K Kondo, K Modis, K Módis, K Módis, K Ono, K Robert, K Wang, K Wilson, K Yao, KL Flannigan, KM Syhr, KN Maclean, KR Olson, KR Olson, L Chang, L Chen, L Gambari, L Li, L Li, L Li, L Li, L Miao, L Miao, L Wang, L Wang, L Xei, LA Harker, LL Pan, M Ackermann, M Goubern, M Liang, M Libiad, M Meier, M Nuño-Ayala, M Okomoto, M Pimentel, M Watanabe, M Whiteman, M Whiteman, M Whiteman, M Whiteman, M Whiteman, M Yang, MA Guzman, MD Fonseca, MH Stipanuk, MH Stipanuk, MK Thorson, MK Thorson, MM Cortese-Krott, MM Cortese-Krott, MP Gallegos-Arreola, MR Filipovic, MR Filipovic, MR Jackson, MW Budde, MY Ali, MY Tsai, N Endo, N Nagahara, N Nagahara, N Shibuya, N Weiss, O Kabil, O Kabil, O Kabil, O Kabil, O Zayachkivska, P Manna, P Nicholls, Peter Rose, Philip K. Moore, PK Yadav, PM Mrozikiewicz, PM Snijder, PS Ganapathy, Q Hu, QH Meng, R Baskar, R Ding, R Greiner, R Kodela, R Picton, R Tocmo, R Tocmo, R Wang, R Yang, RC Zanardo, RH Abeles, RN Carter, RS Beard, S Banu, S Bhattacharyya, S Dayal, S Dayal, S Gupta, S Huang, S Jain, S Jin, S Kundu, S Mani, S Pushpakumar, S Ramasamy, S Saha, S Sen, S Shastry, S Shi, S Xu, SH Cheung, SK Jain, SR Lentz, SY Wu, T Ida, T Itou, T Ivanciuc, T Krejcova, T Takahashi, TJ Lechuga, TM Hildbrant, TT Pan, TW Miller, U Sen, U Sen, U Sen, V Tiranti, V Vitvisky, VE Laubach, W Liu, W Qiao, W Wang, W Washtien, W Zhao, W Zhu, WA Pryor, WJ Cai, X Li, X Shen, X Shen, XH Wang, XQ Tang, XQ Tang, Y Gao, Y Hagiya, Y Hu, Y Kimura, Y Kumai, Y Li, Y Liu, Y Pei, Y Shen, Y Wei, Y Xu, Y Zhou, Yi Zhun Zhu, YJ Peng, Z Guo, Z Jiang, Z Pan, Z Wang, Z Zhang, ZL Clarke, ZZ Xie, ZZ Zhao   +272 more
core   +2 more sources

Redirecting Intermediary Metabolism to Counteract Cyanide Poisoning

The FASEB Journal, Volume 39, Issue 12, 30 June 2025.
Cyanide is coined “the classic metabolic poison”; however, FDA‐approved cyanide chelators do not counteract cyanide's metabolic damage. Here, we review the mechanisms of cyanide toxicity, with a focus on intermediary metabolism. We present the theory that, within the innate plasticity of the metabolome, there may reside metabolic pathways that can ...
Vik S. Bebarta, Anjali K. Nath
wiley   +1 more source

Effects of inhibiting antioxidant pathways on cellular hydrogen sulfide and polysulfide metabolism [PDF]

, 2019
Elaborate antioxidant pathways have evolved to minimize the threat of excessive reactive oxygen species (ROS) and to regulate ROS as signaling entities.
Gao, Yan, Olson, Kenneth R.
core   +1 more source

Modeling fire‐related smoke inhalation injury using the human lung‐on‐a‐chip and organoid platform: Pathogenesis insights and therapeutic evaluation

VIEW, Volume 6, Issue 3, June 2025.
Fire‐related smoke inhalation‐induced acute lung injury (SI‐ALI) poses a significant public health risk, yet effective treatments are limited due to the lack of suitable models. This study developed a more realistic model of SI‐ALI using organ‐on‐a‐chip and organoid technologies, identified key molecules such as catechol‐O‐methyltransferase and ...
Junmin Li, Dezhong Zhang, Yan Meng, Yongqing Chang, Wenbo Wei, Peng Wu, Lin Peng, Wei Chang, Wei Wang, Jie Huang, Jingjing Fang, Keming Zhu, Xiaojian Wan   +12 more
wiley   +1 more source