Results 61 to 70 of about 9,662 (145)

Mycobacterium tuberculosis CysA2 is a dual sulfurtransferase with activity against thiosulfate and 3-mercaptopyruvate and interacts with mammalian cells

open access: yes, 2019
Cyanide is a toxic compound that is converted to the non-toxic thiocyanate by a rhodanese enzyme. Rhodaneses belong to the family of transferases (sulfurtransferases), which are largely studied.
A. Balan   +9 more
core   +1 more source

3-Mercaptopyruvate sulfurtransferase of Leishmania contains an unusual C-terminal extension and is involved in thioredoxin and antioxidant metabolism

open access: yes, 2003
Cytosolic 3-mercaptopyruvate sulfurtransferases (EC 2.8.1.2) of Leishmania major and Leishmania mexicana have been cloned, expressed as active enzymes inEscherichia coli, and characterized.
Williams, Roderick   +11 more
core   +3 more sources

Supersulfide biology and translational medicine for disease control

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 1, Page 115-130, January 2026.
Abstract For decades, the major focus of redox biology has been oxygen, the most abundant element on Earth. Molecular oxygen functions as the final electron acceptor in the mitochondrial respiratory chain, contributing to energy production in aerobic organisms. In addition, oxygen‐derived reactive oxygen species including hydrogen peroxide and nitrogen
Uladzimir Barayeu   +5 more
wiley   +1 more source

Sorghum Poisoning in Livestock: Mechanisms, Risks, and Sustainable Mitigation Strategies

open access: yesInternational Journal of Agronomy, Volume 2026, Issue 1, 2026.
Sorghum (Sorghum bicolor L. Moench) is a drought‐tolerant crop grown in both arid and semiarid regions and serves as both food and fodder. Under environmental stresses, sorghum accumulates cyanogenic glucosides, especially dhurrin. Through ingestion, dhurrin is hydrolyzed into a toxic element called hydrogen cyanide (HCN).
Mahmud Sindid Ikram   +2 more
wiley   +1 more source

Cyanide Beyond Toxicity: A Systematic Review of Its Effects on Vascular Function

open access: yesBasic &Clinical Pharmacology &Toxicology, Volume 137, Issue 5, November 2025.
ABSTRACT Cyanide is widely recognized for its potent toxicity, yet evidence shows that concentrations below 1 μM may enhance cytochrome c oxidase activity and have a regulatory function. Recent findings also demonstrate that mammalian cells, including endothelial cells, produce cyanide endogenously, where it can modulate mitochondrial bioenergetics ...
Elif Alan‐Albayrak, Ulf Simonsen
wiley   +1 more source

Investigation of three accessory subunits of complex I from Yarrowia lipolytica [PDF]

open access: yes, 2010
The nicotinamide-adenine-dinucleotide (NADH):ubiquinone oxidoreductase (complex I) from the strictly aerobic yeast Y. lipolytica contains at least 26 “accessory” subunits however the significance of most of them remains unknown. The aim of this study was
Dobrynin, Krzysztof
core  

Cysteine Signalling in Plant Pathogen Response

open access: yesPlant, Cell &Environment, Volume 48, Issue 10, Page 7107-7122, October 2025.
ABSTRACT The amino acid cysteine is the precursor for a wide range of sulfur‐containing functional molecules in plants, including enzyme cofactors and defence compounds. Due to its redox active thiol group cysteine is highly reactive. Synthesis and degradation pathways are present in several subcellular compartments to adjust the intracellular cysteine
Jannis Moormann   +6 more
wiley   +1 more source

Mechanisms on boron-induced alleviation of aluminum-toxicity in Citrus grandis seedlings at a transcriptional level revealed by cDNA-AFLP analysis.

open access: yesPLoS ONE, 2015
The physiological and biochemical mechanisms on boron (B)-induced alleviation of aluminum (B)-toxicity in plants have been examined in some details, but our understanding of the molecular mechanisms underlying these processes is very limited.
Xin-Xing Zhou   +4 more
doaj   +1 more source

Cyclic AMP Receptor Protein Acts as a Transcription Regulator in Response to Stresses in Deinococcus radiodurans.

open access: yesPLoS ONE, 2016
The cyclic AMP receptor protein family of transcription factors regulates various metabolic pathways in bacteria, and also play roles in response to environmental changes.
Su Yang   +9 more
doaj   +1 more source

MTA‐TST Axis‐Mediated Apoptosis Activation: A Multi‐Omics Insight Into High‐Protein Diet's Anti‐Adiposity Effect

open access: yesFood Science &Nutrition, Volume 13, Issue 7, July 2025.
High protein diet reduced visceral adipose tissue through MTA‐TST‐Bak/Casp‐3 axis, suggesting that MTA has the potential to be developed as a functional substance for obesity prevention and control. ABSTRACT To explore the mechanism of a high‐protein diet (named high protein and rich fat diet, HPRFD) with weight loss effect regulating visceral fat ...
Xinli Yang   +5 more
wiley   +1 more source

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