Results 61 to 70 of about 41,140 (322)

Synthesis and Antiplatelet Activity of Antithrombotic Thiourea Compounds: Biological and Structure-Activity Relationship Studies

Molecules, 2015
The incidence of hematological disorders has increased steadily in Western countries despite the advances in drug development. The high expression of the multi-resistance protein 4 in patients with transitory aspirin resistance, points to the importance ...
André Luiz Lourenço, Max Seidy Saito, Luís Eduardo Gomes Dorneles, Gil Mendes Viana, Plínio Cunha Sathler, Lúcia Cruz de Sequeira Aguiar, Marcelo de Pádula, Thaisa Francielle Souza Domingos, Aline Guerra Manssour Fraga, Carlos Rangel Rodrigues, Valeria Pereira de Sousa, Helena Carla Castro, Lucio Mendes Cabral   +12 more
doaj   +1 more source

A Toolkit for Targeted Neuromodulation of Striatal Direct Pathway Neurons Rescues Parkinsonian Motor Deficits in Mice

Advanced Science, EarlyView.
An adeno‐associated virus (AAV) toolkit enables selective anatomical and functional targeting of striatal D1‐MSNs through retrograde transduction. Enhanced capsids and engineered enhancers drive robust transgene expression across murine and primate models.
Zexuan Hong, Yujing Zhang, Junjiao Zhang, Hanhe Liu, Qiwei Liu, Yanglei Li, Lixin Yang, Lixia Li, Zhongjie Liu, Zhen Yuan, Zhonghua Lu, Yefei Chen, Yuantao Li, Yuwu Jiang, Taian Liu   +14 more
wiley   +1 more source

Novel Guanidine Compound against Multidrug-Resistant Cystic Fibrosis-Associated Bacterial Species

Molecules, 2018
Chronic pulmonary infection is a hallmark of lung disease in cystic fibrosis (CF). Infections dominated by non-fermentative Gram-negative bacilli are particularly difficult to treat and highlight an urgent need for the development of new class of agents ...
Aamer Saeed, Alejandra Bosch, Marisa Bettiol, Diana L. Nossa González, Mauricio Federico Erben, Yanina Lamberti   +5 more
doaj   +1 more source

Electrolyte Additive Strategies in Aqueous Zn‐Ion Batteries: Recent Advances and Prospects

Advanced Science, EarlyView.
This article provides a comprehensive overview of the current status and future development directions of AZIBs electrolyte additives in three aspects: stabilizing zinc anodes (uniform deposition, inhibition of dendritic crystals), protecting cathodes (structural stability, inhibition of dissolution), and enhancing electrolyte stability (wider ...
Yuanze Yu, Hongmin Liu, Long Fan, Huakun Liu, Shixue Dou, Guoxiu Wang, Nana Wang, Zhongchao Bai   +7 more
wiley   +1 more source

Helicene-based Thioureas. [PDF]

, 2017
The main goal of this work was to introduce the helicene moiety into the structure of bis(aryl)thiourea, to prepare a new type of a helicene-based organocatalyst. Several aryl(helicenyl)thioureas were synthesized so far.
Jakubec, Martin
core  

Studies on Diphenyl Lead(IV) Diiodide Complexes of Substituted Thioureas [PDF]

, 1985
Department of Chemistry, Karnatak University, Dharwad-580 003 Manuscript received 27 January 1981, revised 10 November 1983, accepted 8 November 1984 Studies on Diphenyl Lead(IV) Diiodide Complexes of Substituted ...
M. H. SONAR, A. S. R. MURTY
core   +1 more source

Synthesis of 3-(4-(Benzo[d]thiazol-2-yl)phenyl)-5-aryl-1,3,5-oxadiazinane-4-thiones and 1-(4-(Benzo[d]thiazol-2-yl)phenyl)-5-methyl-3-aryl-1,3,5-triazinane-2-thiones

SynOpen, 2018
In this investigation 4-(benzo[d]thiazol-2-yl)benzenamine was reacted with aryl isothiocyanates to give 1-(4-(benzo[d]thiazol-2-yl)phenyl)-3-aryl thioureas 2, which were cyclized with acid to afford 3-(4-(benzo[d]thiazol-2-yl)phenyl)-5-aryl-1,3,5 ...
Pathki Uma, Kamatala Chinna Rajanna, Yelike Hemanth Sriram, Akarapu Premalatha, Pondichery Kuppuswamy Saipraksh   +4 more
doaj   +1 more source

Antileishmanial Thioureas: Synthesis, Biological Activity and in Silico Evaluations of New Promising Derivatives.

Chemical and pharmaceutical bulletin, 2017
Leishmaniasis is a neglected tropical disease caused by protozoan parasites belonging to the genus Leishmania. Currently, the drugs available for treatment of this disease present high toxicity, along with development of parasite resistance.
G. Viana, D. C. Soares, Marcos V. S. Santana, L. H. do Amaral, P. Meireles, Raquel Pinto Nunes, L. C. DA SILVA, L. S. Aguiar, C. R. Rodrigues, V. P. de Sousa, H. Castro, P. Abreu, P. Sathler, E. Saraiva, L. Cabral   +14 more
semanticscholar   +1 more source

Spike‐Embedded Nanocatalysts via Metal‐Directed Carbonization for Highly Efficient and Robust Semi‐Hydrogenation

Advanced Science, EarlyView.
A metal‐directed carbonization strategy transforms hierarchical organic microspheres into spiky carbon catalysts with Pd nanoparticles embedded at the tips. This approach resolves the activity‐stability trade‐off, achieving exceptional poison resistance in semi‐hydrogenations, offering a versatile, scalable platform for designing high‐performance ...
Yintao Li, Yang Sun, Minghang Li, Wenxuan Zhang, Zhengtao Li, Yihao Ni, Yao Zhang, Yong Wang, Samuel S. Veroneau, Pengfei Ji   +9 more
wiley   +1 more source

C NMR study of 1,3-pyridylmethyl ureas and -thioureas [PDF]

, 1985
The $^13C$ NMR spectra of several 1,3-pyridylmethyl ureas and their corresponding thioureas have been obtained. The $^13C$ chemical shifts, and the direct and long range $^13C$ ---$^1H$ coupling constants have been deduced.
Sudha, LV, Sathyanarayana, DN
core